13 mayo | 2026 Expanding Bevacizumab-Erlotinib Therapy Through Fumarate Hydratase Deficiency Screening and Drug Target Pathway Analysis in Papillary Morphology Metastatic Renal Cell Carcinoma. de Nicolás-Hernández, J, Valdivia, C, Arenas, A, Zaballos, MA , Robledo, M, Rodríguez-Antona, C . Eur Urol (PMID: 42128750) (doi:10.1016/j.eururo.2026.04.026)
12 mayo | 2026 Therapeutic properties of ayahuasca component N,N-Dimethyltryptamine in a pre-clinical model of Parkinson's disease. Calleja-Conde, J, Echeverry-Alzate, V, Sanz-SanCristobal, M , Alonso-Gil, S , Giné, E, Bühler, K, López-Moreno, JA, Perez-Castillo, A , Morales-Garcia, JA . Exp Neurol (PMID: 42128256) (doi:10.1016/j.expneurol.2026.115822)
11 mayo | 2026 Analysis of UGT1A1 germline variants in patients with advanced breast cancer treated with trastuzumab-deruxtecan: results from the PROCURE Project. Sánchez-Bayona, R, de Nicolás-Hernández, J , Saura, C, Gion, M, Cejalvo, JM, Llabrés, E, Cortés, J, Falcón, A, Pernas, S, López de Sa, A, Vidal, M, Hinojo, C, Curiel, T, Cruz, J, Martínez, V, Cantos, B, Echarri, MJ, Gallegos, I, Bueno, C, Vargas, AM, Escrivá-de-Romaní, S, Fullana, B, Cobos, MA, Arenas, A , Joval-Ramentol, L, Ortiz, P, Pascual, T, Valdivia, C , Villacampa, G, Ciruelos, E, Rodriguez-Antona, C . ESMO Open - 11 (5) : 107695 (PMID: 42114485) (doi:10.1016/j.esmoop.2026.107695)
5 mayo | 2026 Correction: Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection. Esteban-Ortega, GM , Torres-Campos, E , Díaz-Guerra, M . Cell Death Dis - 17 (1) (PMID: 42086552) (doi:10.1038/s41419-026-08785-z)
4 mayo | 2026 FGFR1 drives metabolic adaptation associated with temozolomide resistance in glioblastoma. Zarzuela, L, López-Cepero, IG, Rattigan, KM, Reina-Bando, A, Martín-Montalvo, J, Sierra-Párraga, JM, Sánchez-Escabias, E, Morillo-Huesca, M, Oltra, SS , Ceballos-Chávez, M, Capilla-González, V, Moreno-Bueno, G , Murdoch, PDS, Reyes, JC, Helgason, GV, Tomé, M, Durán, RV. Cancer Lett - 652 : 218565 (PMID: 42092681) (doi:10.1016/j.canlet.2026.218565)
2 mayo | 2026 Resistance to tumorigenesis in the african spiny mouse (Acomys) correlates with upregulation of multiple tumor suppressor genes. Vitorino, M, Pinheiro, GG, Grenho, I, Araujo, IM, Ferreira, BI, Link, W , Tiscornia, G. Sci Rep (PMID: 42069753) (doi:10.1038/s41598-026-45001-6)
1 mayo | 2026 Chromosomal Rearrangements Identified in Three Additional Patients With Generalized Congenital Hypertrichosis With Gingival Hyperplasia Involving the 17q24.2-q24.3 Locus. Tenorio-Castano, J, Feito, M, de Lucas, R, Sendagorta, E, Gómez-Fernández, C, Parra, A, Vallespin, E, Gallego-Zazo, N, Cazalla, M, Jiménez-Estrada, JA, Miranda-Alcaraz, L, Mora-Gómez, M, Rodríguez-Canó, MJ, Vázquez-Amell, V, Ramos, S, Valle, T, Mansilla, E, Santiago, FG, Galán-Gómez, E, Calpena, E, Ruíz-Pérez, VL, Nevado, J , Lapunzina, P. Clin Genet - 109 (5) : 904-911 (PMID: 41574449) (doi:10.1111/cge.70133)
29 abr | 2026 Clinical spectrum, diagnosis, cognitive outcomes and therapeutic strategies in pediatric Rasmussen syndrome: a 10-year cohort from a tertiary pediatric center. Cantarín-Extremera, V, Ballarà-Petitbò, M, Jiménez-Legido, M, Esteso-Orduña, B, Muñiz, IS, Cámara-Barrio, S, Cancho-Candela, R, Pérez-Jiménez, MA, Duat-Rodriguez, A, Guerrero-López, R . Orphanet J Rare Dis (PMID: 42057109) (doi:10.1186/s13023-026-04357-8)
28 abr | 2026 Evaluation of Self-Illuminating Nanoconjugates Against Pancreatic Ductal Adenocarcinoma. Abal-Sanisidro, M, Ruiz-Cañas, L , Batres-Ramos, S , Blanco, MG, García-Bermejo, ML, García-Fernández, J, Rodríguez-Cobo, L, López-Higuera, JM, Sainz, B , de la Fuente, M. Int J Nanomedicine - 21 : 545161 (PMID: 42079438) (doi:10.2147/IJN.S545161)
28 abr | 2026 Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off-the-shelf targeted NGS panel. Casas-Arozamena, C, Lande, KT, Diaz, E, Vilar, A, Cueva, J, Arias, E, Sampayo, V, Abalo, A, González, N, Colás, E, Gil-Moreno, A, Abal, M, Moreno-Bueno, G , Sørlie, T, Lindemann, K, Muinelo-Romay, L. Mol Oncol (PMID: 42047179) (doi:10.1002/1878-0261.70246)
26 abr | 2026 Investigation of multilocus imprinting disturbance (MLID) in 101 Beckwith-Wiedemann spectrum patients. Cazalla, M, Parra, A, Rodríguez-Antolín, C, Silván, C, Miranda-Alcaraz, L, Mora-Gómez, M, Gallego-Zazo, N, Rodríguez-Canó, M, Jiménez-Estrada, JA, Arias, P, Gomez, EG, González-Meneses, A, Barbero, P, Lotersztein, V, , , Hildonen, M, Tümer, Z, Santana, A, Ramos, F, Ruiz-Perez, VL , Tenorio-Castano, J, Nevado, J , Monk, D, Lapunzina, P. Clin Epigenetics (PMID: 42036661) (doi:10.1186/s13148-026-02077-1)
22 abr | 2026 Editorial: Integrating imaging techniques to enhance precision in cancer immunotherapy. Pacheco-Torres, J . Front Oncol - 16 : 1819541 (PMID: 42100435) (doi:10.3389/fonc.2026.1819541)
22 abr | 2026 QBP1 Peptide as a Potential Anti-Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study. Tejero-Ojeda, MM, Vives, AB, Wojciechowski, M, Pham, DQH, Chwastyk, M, Vallejo, M , Novials, A, Laurents, DV, Carrión-Vázquez, M. Adv Sci (Weinh) (PMID: 42017387) (doi:10.1002/advs.202508344)
16 abr | 2026 A CXCR4 targeting peptide delivered by silica nanoparticles eliminates migrating cancer stem cells in pancreatic ductal adenocarcinoma. Tiwary, K, Lahusen, A, Inaas, S, Beitzinger, B, Schmid, R, Harms, M, Hauff, S, Arnold, F, Walter, K, Alcala, S , Hahn, S, Heßmann, E, Kleger, A, Azoitei, N, Seufferlein, T, Sainz, B , Münch, J, Lindén, M, Hermann, PC. Sci Rep - 16 (1) (PMID: 41991735) (doi:10.1038/s41598-026-48584-2)
16 abr | 2026 Targeting pyroptosis in tauopathies: A redox-driven axis of neuroinflammation and neurodegeneration. Alonso-López, E, Silva-Llanes, I , Díez-Tejedor, E, Lastres-Becker, I . Free Radic Biol Med - 251 : 212-228 (PMID: 42000084) (doi:10.1016/j.freeradbiomed.2026.04.029)
10 abr | 2026 Intramuscular Transplantation of Human Pluripotent Stem Cell-derived Pancreatic Endocrine Cells in Mice. Hernanz, M , Matas, D , Mirasierra, M , García, G, Vallejo, M , Bartolomé, A . J Vis Exp (PMID: 42044039) (doi:10.3791/69562)
1 abr | 2026 Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma. Zwimpfer, TA, Fereday, S, Pandey, A, Ariyaratne, D, Jayawardana, MW, Twomey, L, Laumont, CM, Kennedy, CJ, Bolithon, A, Meagher, NS, Milne, K, Hamilton, P, Alsop, J, Antoniou, AC, Au-Yeung, G, Beckmann, MW, Berrington de Gonzalez, A, Bisinotto, C, Blome, F, Bodelon, C, Boros, J, Brand, AH, Carney, ME, Cazorla-Jiménez, A, Chiu, DS, Christie, EL, Chudecka-Głaz, A, Coulson, P, Cushing-Haugen, KL, Cybulski, C, Darcy, KM, David, C, Davidson, T, Ekici, AB, Elishaev, E, Emons, J, Engler, T, Farrell, R, Fischer, A, García-Closas, M, Gentry-Maharaj, A, Ghatage, P, Glasspool, R, Harter, P, Hartkopf, AD, Hartmann, A, Heikaus, S, Hernandez, BY, Hettiaratchi, A, Heublein, S, Huntsman, DG, Jimenez-Linan, M, Jones, ME, Kang, E, Kaznowska, E, Kluz, T, Kommoss, FKF, Konecny, G, Kruitwagen, RFPM, Kwon, J, Lambrechts, D, Lee, CH, Lester, J, Leung, SCY, Leung, Y, Linder, A, Lissowska, J, Loverix, L, Lubiński, J, Mateoiu, C, McNeish, IA, Moubarak, M, Nelson, GS, Nevins, N, Olawaiye, AB, Olbrecht, S, Orsulic, S, Osorio, A, Quinn, CM, Mohan, GR, Ray-Coquard, I, Rodríguez-Antona, C , Roxburgh, P, Ruebner, M, Salfinger, SG, Samra, S, Schoemaker, MJ, Sinn, HP, Sonke, GS, Steele, L, Stewart, CJR, Talhouk, A, Tan, A, Tarney, CM, Taylor, SE, Van de Vijver, KK, van der Aa, MA, Van Gorp, T, Van Nieuwenhuysen, E, Van-Wagensveld, L, Wahner-Hendrickson, AE, Walter, C, Wang, C, Welz, J, Wentzensen, N, Wilkens, LR, Winham, SJ, Winterhoff, B, Anglesio, MS, Berchuck, A, Candido Dos Reis, FJ, Cohen, PA, Conrads, TP, Crowe, P, Doherty, JA, Fasching, PA, Fortner, RT, García, MJ , Gayther, SA, Goodman, MT, Gronwald, J, Harris, HR, Heitz, F, Horlings, HM, Karlan, BY, Kelemen, LE, Larry Maxwell, G, Menon, U, Modugno, F, Neuhausen, SL, Schildkraut, JM, Staebler, A, Sundfeldt, K, Swerdlow, AJ, Vergote, I, Wu, AH, Brenton, JD, Pharoah, PDP, Pearce, CL, Pike, MC, Goode, EL, Ramus, SJ, Köbel, M, Nelson, BH, DeFazio, A, Friedlander, ML, Bowtell, DDL, Garsed, DW. Nat Commun (PMID: 41922350) (doi:10.1038/s41467-026-71134-3)
1 abr | 2026 Tn-seq of Thermus thermophilus Genome Reveals Unexpected Tolerance to Insertions in Bacterial Common Essential Genes. Gómez-Campo, CL, Gost, M, de Sousa, BFS, Álvarez, L, Berenguer, J, Redrejo-Rodríguez, M , Mencía, M. Microbiologyopen - 15 (2) : e70207 (PMID: 41853935) (doi:10.1002/mbo3.70207)
25 mar | 2026 Correction to "Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer". Masci, D, Ling, L, Yang, L, Puxeddu, M, Colla, C, Nalli, M, Coluccia, A, Santelli, M, Sciò, P, Cuřínová, P, Ansari, MSZ, Naro, C, Sette, C, Jimenez, L , Link, W , Bigogno, C, Dondio, G, Hamel, E, Liu, T, Silvestri, R, La Regina, G. J Med Chem (PMID: 41878875) (doi:10.1021/acs.jmedchem.6c00834)
23 mar | 2026 Transcriptomic profile of embryoid bodies under hypoxia at single cell level. Acosta-Iborra, B , Berrouayel, Y , Puente-Santamaría, L , Del Peso, L , Jiménez, B . GigaByte - 2026 : gigabyte178 (PMID: 41939141) (doi:10.46471/gigabyte.178)
22 mar | 2026 A New Patient With SPOUT1-Related Neurodevelopmental Disorder Identified by Genomic Data Re-Analysis: Novel Phenotypic Features and Literature Review. Valle, T, Damián, A, Torres, M, Méndez, P, Márquez, A, Cazalla, M, Jiménez-Estrada, JA, Rodríguez-Canó, M, Gallego-Zazo, N, Vásquez-Amell, V, Miranda Alcaraz, L, Mora-Gómez, M, Ruiz Pérez, VL , Nevado, J , Tenorio-Castaño, J, Morte, B , Carracedo, Á, Lapunzina, P, Galán, E. Am J Med Genet A (PMID: 41866812) (doi:10.1002/ajmg.a.70126)
21 mar | 2026 Identification of a new selective ligand for targeting neuronal KV4.3/KChIP3 over cardiac KV4.3/KChIP2 channels. Socuellamos, PG , Viedma-Barba, C, de Benito-Bueno, A , Bonache, MA, Ropero, M , Diez, S , Elizalde, P, Marín-Olivero, I, Redondo-Moya, M , Naranjo, JR, Gonzalez-Vera, JA, Orte, A, Perez-Lara, A, Martin-Martinez, M, Valenzuela, C , Gutierrez-Rodriguez, M. Biochem Pharmacol - 249 : 117921 (PMID: 41871718) (doi:10.1016/j.bcp.2026.117921)
19 mar | 2026 Lgi3-4 proteins modulate the KV1.5 channelosome and are potential therapeutic targets for atrial fibrillation. Socuéllamos, PG , Macías, Á , de Benito-Bueno, Á , Cruz, FM, Redondo-Moya, M , Coronado, MJ, Ramil, E, Rosado, S, Rios-Rosado, EC, Valencia-Avezuela, M , Andrés-Delgado, L, Blázquez, JA, Forteza-Gil, A, Gutiérrez-Rodríguez, M, Jalife, J, Valenzuela, C . Cardiovasc Res (PMID: 41854369) (doi:10.1093/cvr/cvag049)
16 mar | 2026 Brain Permeable SGK1 Inhibitors: A Promising Therapeutic Strategy for Neurodegenerative Diseases. Madruga, E, Garcia-Rubia, A, Sanchez-Nuñez, C, Martinez-Gonzalez, L, Fernandez-Escamilla, AM, Lastres-Becker, I , Gil, C, Martinez, A. J Med Chem (PMID: 41837733) (doi:10.1021/acs.jmedchem.5c03050)
14 mar | 2026 Perinatal liver sympathetic innervation governs body size. Bobo-Jimenez, V, Gomila, S, Lapresa, R, Agulla, J, Angibaud, J, Sanchez-Moran, I, Delgado-Esteban, M, González-Rodriguez, A , Fernández-Jaén, A, Ramos-Cabrer, P, Nägerl, UV, Bolaños, JP, Almeida, A. Commun Biol (PMID: 41826417) (doi:10.1038/s42003-026-09880-9)
10 mar | 2026 Hypoxemia-induced TIGIT expression in obstructive sleep apnea is reversible with continuous positive airway pressure. Pérez-Moreno, P, Díaz-García, E, López-Fernández, C, García-Sánchez, A, Mañas, E, Pozuelo-Sánchez, L, Torres-Vargas, M, Martínez-Cerón, E, Casitas, R, Galera, R, Fernández Velasco, M, Del Peso, L , García-Río, F, Cubillos-Zapata, C. Front Immunol - 17 : 1769874 (PMID: 41884850) (doi:10.3389/fimmu.2026.1769874)
10 mar | 2026 Therapeutic potential of isothiocyanates by targeting the NRF2 pathway. García-Yagüe, ÁJ , Cazalla, E , Cuadrado, A . Free Radic Biol Med - 248 : 554-596 (PMID: 41819504) (doi:10.1016/j.freeradbiomed.2026.03.029)
4 mar | 2026 A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential. Jiménez-Castaño, R, Narwade, N, Moreno-Bueno, G , Sánchez-Laorden, B, Galcerán, J, Youssef, KK, Nieto, MA. Nat Commun (PMID: 41781391) (doi:10.1038/s41467-026-70242-4)
2 mar | 2026 Hexaraphane as a potential therapeutic strategy for tauopathies. García-Yagüe, ÁJ , Carnicero-Senabre, D , Núñez, Á, Cipriani, R, Capetillo-Zarate, E, Escoll, M , Okunishi, I, Rojo, AI , Cuadrado, A . Redox Biol - 92 : 104107 (PMID: 41785736) (doi:10.1016/j.redox.2026.104107)
1 mar | 2026 Molecular profiling unveils genetic complexity and identifies potential new driver mechanisms in head and neck paragangliomas. Mellid, S, Caleiras, E, Martínez-Montes, ÁM, Arenas, A, Jiménez, S, Monteagudo, M, Letón, R, Radu, R, Álvarez-Díaz, R, Arroba, E, Diaz-Talavera, A, Martínez-Puente, N, Álvarez-Escolá, C, Pineda, M, Balbín, M, Al-Shahrour, F, Rodriguez-Antona, C , Montero-Conde, C , Leandro-García, LJ, Honrado, E, Soria-Tristán, M, Robledo, M, Cascón, A. Genes Dis - 13 (2) : 101705 (PMID: 41216501) (doi:10.1016/j.gendis.2025.101705)
26 feb | 2026 CoQ0 hysteresis and inhibition of the cytochrome b5 reductase activity of human Cb5R by CoQ0 and CoQ10. Valerio, GN, Martinez-Costa, OH , Sanchez-Cabeza, C , Cordas, CM, Samhan-Arias, AK . Free Radic Biol Med (PMID: 41763501) (doi:10.1016/j.freeradbiomed.2026.02.065)
25 feb | 2026 4-(5-Chloro-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-yl)benzenesulfonamide: A Novel Polypharmacology Agent to Target Carbonic Anhydrase IX and XII With Improved Selectivity, Wnt/β-Catenin Signaling Pathway, and P-Glycoprotein. Puxeddu, M, Bordone, R, Colla, C, Rotili, G, Coluccia, A, Sciò, P, Cuřínová, P, Nocentini, A, Supuran, CT, Filiberti, S, Turati, M, Ronca, R, Kopecka, J, Riganti, C, Jimenez, L , Link, W , Bigogno, C, Dondio, G, Barba, M, Canettieri, G, Silvestri, R, La Regina, G. ChemMedChem - 21 (4) : e202500996 (PMID: 41739665) (doi:10.1002/cmdc.202500996)
24 feb | 2026 Structural features and antibacterial activity of Ni(II) thiosemicarbazones in a zirconium metal-organic framework composite. Loukopoulos, E, Fabra, D, Melones-Herrero, J , Matesanz, AI, Viciana, C, Platero-Prats, AE, Sánchez-Pérez, I , Quiroga, AG. Dalton Trans (PMID: 41734171) (doi:10.1039/d5dt03008k)
13 feb | 2026 Correction: Case Report: Autosomal recessive palmoplantar keratoderma with additional bilateral hearing loss due to a pathogenic frameshift deletion in FAM83G. Mora-Gómez, M, Feito, M, Gallego-Zazo, N, Maseda-Pedrero, R, Sobral-Costas, TG, Miranda-Alcaraz, L, Vásquez-Amell, V, Rodríguez-Canó, M, Parra, A, Cazalla, M, Arias, P, Silván, C, Jiménez-Estrada, JA, Ruiz-Pérez, VL , Nevado, J , Lapunzina, P, Tenorio-Castano, J. Front Med (Lausanne) - 13 : 1779531 (PMID: 41767504) (doi:10.3389/fmed.2026.1779531)
10 feb | 2026 A single-step radiolabeling strategy for PET, SPECT, and therapeutic radionuclides using nanoparticles as a universal chelator. Herraiz, A, Rodríguez-San-Pedro, A, Casquero-Veiga, M, Cossío, U, Arias-Ramos, N , Gutiérrez, L, Romero-Sanz, E, Luján-Rodríguez, VM, Cerón, C, Oteo, M, González-Paredes, A, López-Larrubia, P , Rosales, RTM, Cortes-Canteli, M , Morcillo, MA, Ruiz-Cabello, J, Pellico, J, Herranz, F. Npj Imaging - 4 (1) : 8 (PMID: 41667650) (doi:10.1038/s44303-026-00142-1)
10 feb | 2026 Protective effect of melatonin against age-related ischemia-reperfusion injury is associated with the NLRP3 inflammasome pathway. Ben Jeddou, I, Berlana, Á , Rey, E, Ben Abdennebi, H, Almawi, WY, Omri, A, Valverde, ÁM , González-Rodriguez, Á , Zaouali, MA. J Physiol Biochem - 82 (1) : 9 (PMID: 41665836) (doi:10.1007/s13105-026-01145-7)
6 feb | 2026 A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer. Centonze, A, Roura, AJ, Novillo-Font, M, Giordano, C, Hernando-Momblona, X, Llanses, M, Prats, P, Sevillano, M, Cabot, D, Novell, M, Pabst, G, Andersch, F, Cañellas-Socias, A, Zhang, C, Giakoumakis, NN, Sparks, H, Dunsby, C, Colombelli, J, Fernández-Barral, A , Sancho, E, Stephan-Otto Attolini, C, Muñoz, A , Barbachano, A , Palmer, HG , Martínez-Quintanilla, J, Zuber, J, Blaj, C, Quintana, E, Cortina, C, Marti-Renom, MA, Batlle, E. Cancer Discov - 16 (2) : 320-344 (PMID: 41128661) (doi:10.1158/2159-8290.CD-25-0679)
4 feb | 2026 VCAN Is Essential for ERK5-Driven Tumorigenesis in Soft Tissue Sarcoma. Jiménez-Suárez, J, Cimas, FJ, Paricio, JJ, Belandia, B , Berrouayel, Y , Arconada-Luque, E, Matilla-Almazán, S, Soffientini, C, Percio, S, Redondo-García, S, García-Flores, N, Garnés-García, C, Fernández-Aroca, P, Martínez-Gómez, JJ, Fernández-Aramburo, A, Nam-Cha, SH, Rovida, E, Pandiella, A, Esparís-Ogando, A, Pasquali, S, Rodríguez-Manzaneque, JC, Del Peso, L , Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . Int J Biol Sci - 22 (5) : 2452-2468 (PMID: 41800245) (doi:10.7150/ijbs.121402)
3 feb | 2026 Bioinformatic Analyses of the Ataxin-2 Family Since Algae Emphasize Its Small Isoforms, Large Chimerisms, and the Importance of Human Exon 1B as Target of Therapies to Prevent Neurodegeneration. Auburger, GWJ, Key, J, Gispert, S, Lastres-Becker, I , Almaguer-Mederos, LE, Bassa, C, Auburger, A, Auburger, G, Arsovic, A, Deller, T, Sen, NE. Int J Mol Sci - 27 (3) (PMID: 41683920) (doi:10.3390/ijms27031499)
28 ene | 2026 A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages. Dunphy, G, Adán-Barrientos, I, Fernández-Delgado, I, Villarroya-Beltri, C, Heras-Murillo, I, Moya-Ruiz, E, Sánchez-Álvarez, M , Jarit-Cabanillas, A, Del Pozo, MA, Guerra, S, Sánchez-Madrid, F, Sancho, D. Immunity (PMID: 41610845) (doi:10.1016/j.immuni.2025.12.010)
23 ene | 2026 The inhibition of Il1β synthesis mediated by a novel pyridine-sulfonamide compound protects against the progression of metabolic dysfunction-associated steatotic liver disease. Berlana, Á , Rey, E, Fresno-Ventura, E , Gomez-Gutierrez, P, Vega, M, García-Monzón, C, González-Rodríguez, Á . Biomed Pharmacother - 195 : 119052 (PMID: 41579710) (doi:10.1016/j.biopha.2026.119052)
16 ene | 2026 PPARβ/δ contributes to the antidiabetic effect and the increase in GDF15 caused by metformin. Jurado-Aguilar, J, Barroso, E, Rada, P , Peyman, M, Rostami, A, Balsinde, J, Valverde, ÁM , Wahli, W, Palomer, X, Vázquez-Carrera, M. Acta Pharmacol Sin (PMID: 41545750) (doi:10.1038/s41401-025-01705-5)
14 ene | 2026 Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1. Hank, EC, D'Arcy-Evans, ND, Scaletti, ER, Benítez-Buelga, C , Wallner, O, Ortis, F, Zhou, K, Meng, L, Del Prado, A, Calvo, P, Almlöf, I, Wiita, E, Nierlin, K, Košenina, S, Krämer, A, Eddershaw, A, Kehler, M, Long, M, Jemth, AS, Dawson, H, Stewart, J, Dickey, A, Astorga, ME, Varga, M, Homan, EJ, Scobie, M, Knapp, S, Sastre, L , Stenmark, P, de Vega, M, Helleday, T, Michel, M. RSC Chem Biol - 7 (1) : 169-181 (PMID: 41195166) (doi:10.1039/d4cb00323c)
14 ene | 2026 Synergistic regulatory mechanisms in glycolysis revealed by pathway transplantation. Knibbe, E, Boonekamp, FJ, Stuij, R, Savakis, P, Pelsma, KAJ, Jansen, L, Flores, C-L , Teusink, B, Daran-Lapujade, P. mBio - 17 (1) : e0021925 (PMID: 41532746) (doi:10.1128/mbio.00219-25)
13 ene | 2026 Modulation of the Receptor Tyrosine Kinase TIE2/Tek Pathway by NRF2 Activation in Neurovascular Endothelial Cells. Cazalla, E , García-Yagüe, ÁJ , Pajares, M , Jiménez-Villegas, J , Escoll, M , Rojo, AI , Cuadrado, A . Int J Mol Sci - 27 (2) (PMID: 41596422) (doi:10.3390/ijms27020770)
13 ene | 2026 NRF2 AT THE CROSSROADS OF PARKINSON'S DISEASE AND AGING: MECHANISTIC INSIGHTS AND TRANSLATIONAL PERSPECTIVES. Áj, GY , N, E, Dinkova-Kostova, AT, Ai, R , Pg, S, A, D, V, T, van Goor, H, Lastres-Becker, I . Free Radic Biol Med (PMID: 41539374) (doi:10.1016/j.freeradbiomed.2026.01.023)
7 ene | 2026 Enhancing TFEA.ChIP with ENCODE regulatory maps for generalizable transcription factor enrichment. Berrouayel, Y , Del Peso, L . Brief Bioinform - 27 (1) (PMID: 41527853) (doi:10.1093/bib/bbaf715)
6 ene | 2026 Uncovering the Role of Thrombospodin-1 and Occludin as Potential Prognostic and Diagnostic Biomarkers in Traumatic Brain Injury. Decouty-Pérez, C, Valencia, I, Alvarez-Rubal, M, Martínez-Cuevas, E, Farré-Alins, V, Calzada, MJ, Penalba, A, Montaner, J, Rodríguez de Cía, J, Taravilla-Loma, M, Hernández-García, BJ, Fuertes-Yebra, E, González-Rodríguez, Á , Lopez-Rodriguez, AB, Egea, J. Int J Mol Sci - 27 (2) (PMID: 41596222) (doi:10.3390/ijms27020571)
5 ene | 2026 De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function. Bessler, N, Wezenaar, AKL, Ariese, HCR, Honhoff, C, Dommann, N, Wehrens, EJ, Ruiz Moreno, C, van den Broek, TJM, Collot, RVU, Kloosterman, DJ, Keramati, F, Roosen, M, de Blank, S, van Vliet, E, Barrera Román, M, Gatti, LCDE, Ertürk, A, Kuball, J, Sebestyén, Z, Kool, M, Patrizi, S, Miele, E, Künkele, A, Kranendonk, MEG, Cornel, AM, Nierkens, S, Mayer, C, Stunnenberg, HG, Alemany, A, Alieva, M , Rios, AC. Nat Cancer (PMID: 41492091) (doi:10.1038/s43018-025-01084-0)
5 ene | 2026 GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model. Silva-Llanes, I , Smith, LA , Abdelkader-Guillén, A , Jiménez-Villegas, J , Sarrió, D , Moreno-Bueno, G , Lastres-Becker, I . J Biomed Sci - 33 (1) : 6 (PMID: 41486173) (doi:10.1186/s12929-025-01210-1)
2 ene | 2026 Assessing Amplification Quality and Bias in MDA Methods Through Comparative Analysis of Short-Read Sequencing. Lozano-Escobar, ED , Mateo-Cáceres, V , Mayoral-Campos, C , Redrejo-Rodríguez, M . Methods Mol Biol - 3003 : 131-148 (PMID: 41478953) (doi:10.1007/978-1-0716-5060-8_10)