25 Mar | 2026 Correction to "Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer". Masci, D, Ling, L, Yang, L, Puxeddu, M, Colla, C, Nalli, M, Coluccia, A, Santelli, M, Sciò, P, Cuřínová, P, Ansari, MSZ, Naro, C, Sette, C, Jimenez, L , Link, W , Bigogno, C, Dondio, G, Hamel, E, Liu, T, Silvestri, R, La Regina, G. J Med Chem (PMID: 41878875) (doi:10.1021/acs.jmedchem.6c00834)
22 Mar | 2026 A New Patient With SPOUT1-Related Neurodevelopmental Disorder Identified by Genomic Data Re-Analysis: Novel Phenotypic Features and Literature Review. Valle, T, Damián, A, Torres, M, Méndez, P, Márquez, A, Cazalla, M, Jiménez-Estrada, JA, Rodríguez-Canó, M, Gallego-Zazo, N, Vásquez-Amell, V, Miranda Alcaraz, L, Mora-Gómez, M, Ruiz Pérez, VL , Nevado, J , Tenorio-Castaño, J, Morte, B , Carracedo, Á, Lapunzina, P, Galán, E. Am J Med Genet A (PMID: 41866812) (doi:10.1002/ajmg.a.70126)
21 Mar | 2026 Identification of a new selective ligand for targeting neuronal KV4.3/KChIP3 over cardiac KV4.3/KChIP2 channels. Socuellamos, PG , Viedma-Barba, C, de Benito-Bueno, A , Bonache, MA, Ropero, M , Diez, S , Elizalde, P, Marín-Olivero, I, Redondo-Moya, M, Naranjo, JR, Gonzalez-Vera, JA, Orte, A, Perez-Lara, A, Martin-Martinez, M, Valenzuela, C , Gutierrez-Rodriguez, M. Biochem Pharmacol - 249 : 117921 (PMID: 41871718) (doi:10.1016/j.bcp.2026.117921)
16 Mar | 2026 Brain Permeable SGK1 Inhibitors: A Promising Therapeutic Strategy for Neurodegenerative Diseases. Madruga, E, Garcia-Rubia, A, Sanchez-Nuñez, C, Martinez-Gonzalez, L, Fernandez-Escamilla, AM, Lastres-Becker, I , Gil, C, Martinez, A. J Med Chem (PMID: 41837733) (doi:10.1021/acs.jmedchem.5c03050)
10 Mar | 2026 Hypoxemia-induced TIGIT expression in obstructive sleep apnea is reversible with continuous positive airway pressure. Pérez-Moreno, P, Díaz-García, E, López-Fernández, C, García-Sánchez, A, Mañas, E, Pozuelo-Sánchez, L, Torres-Vargas, M, Martínez-Cerón, E, Casitas, R, Galera, R, Fernández Velasco, M, Del Peso, L , García-Río, F, Cubillos-Zapata, C. Front Immunol - 17 : 1769874 (PMID: 41884850) (doi:10.3389/fimmu.2026.1769874)
10 Mar | 2026 Therapeutic potential of isothiocyanates by targeting the NRF2 pathway. García-Yagüe, ÁJ , Cazalla, E , Cuadrado, A . Free Radic Biol Med - 248 : 554-596 (PMID: 41819504) (doi:10.1016/j.freeradbiomed.2026.03.029)
4 Mar | 2026 A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential. Jiménez-Castaño, R, Narwade, N, Moreno-Bueno, G , Sánchez-Laorden, B, Galcerán, J, Youssef, KK, Nieto, MA. Nat Commun (PMID: 41781391) (doi:10.1038/s41467-026-70242-4)
2 Mar | 2026 Hexaraphane as a potential therapeutic strategy for tauopathies. García-Yagüe, ÁJ , Carnicero-Senabre, D , Núñez, Á, Cipriani, R, Capetillo-Zarate, E, Escoll, M , Okunishi, I, Rojo, AI , Cuadrado, A . Redox Biol - 92 : 104107 (PMID: 41785736) (doi:10.1016/j.redox.2026.104107)
1 Mar | 2026 Molecular profiling unveils genetic complexity and identifies potential new driver mechanisms in head and neck paragangliomas. Mellid, S, Caleiras, E, Martínez-Montes, ÁM, Arenas, A, Jiménez, S, Monteagudo, M, Letón, R, Radu, R, Álvarez-Díaz, R, Arroba, E, Diaz-Talavera, A, Martínez-Puente, N, Álvarez-Escolá, C, Pineda, M, Balbín, M, Al-Shahrour, F, Rodriguez-Antona, C , Montero-Conde, C , Leandro-García, LJ, Honrado, E, Soria-Tristán, M, Robledo, M, Cascón, A. Genes Dis - 13 (2) : 101705 (PMID: 41216501) (doi:10.1016/j.gendis.2025.101705)
26 Feb | 2026 CoQ0 hysteresis and inhibition of the cytochrome b5 reductase activity of human Cb5R by CoQ0 and CoQ10. Valerio, GN, Martinez-Costa, OH , Sanchez-Cabeza, C , Cordas, CM, Samhan-Arias, AK . Free Radic Biol Med (PMID: 41763501) (doi:10.1016/j.freeradbiomed.2026.02.065)
25 Feb | 2026 4-(5-Chloro-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-yl)benzenesulfonamide: A Novel Polypharmacology Agent to Target Carbonic Anhydrase IX and XII With Improved Selectivity, Wnt/β-Catenin Signaling Pathway, and P-Glycoprotein. Puxeddu, M, Bordone, R, Colla, C, Rotili, G, Coluccia, A, Sciò, P, Cuřínová, P, Nocentini, A, Supuran, CT, Filiberti, S, Turati, M, Ronca, R, Kopecka, J, Riganti, C, Jimenez, L , Link, W , Bigogno, C, Dondio, G, Barba, M, Canettieri, G, Silvestri, R, La Regina, G. ChemMedChem - 21 (4) : e202500996 (PMID: 41739665) (doi:10.1002/cmdc.202500996)
24 Feb | 2026 Structural features and antibacterial activity of Ni(II) thiosemicarbazones in a zirconium metal-organic framework composite. Loukopoulos, E, Fabra, D, Melones-Herrero, J , Matesanz, AI, Viciana, C, Platero-Prats, AE, Sánchez-Pérez, I , Quiroga, AG. Dalton Trans (PMID: 41734171) (doi:10.1039/d5dt03008k)
13 Feb | 2026 Correction: Case Report: Autosomal recessive palmoplantar keratoderma with additional bilateral hearing loss due to a pathogenic frameshift deletion in FAM83G. Mora-Gómez, M, Feito, M, Gallego-Zazo, N, Maseda-Pedrero, R, Sobral-Costas, TG, Miranda-Alcaraz, L, Vásquez-Amell, V, Rodríguez-Canó, M, Parra, A, Cazalla, M, Arias, P, Silván, C, Jiménez-Estrada, JA, Ruiz-Pérez, VL , Nevado, J , Lapunzina, P, Tenorio-Castano, J. Front Med (Lausanne) - 13 : 1779531 (PMID: 41767504) (doi:10.3389/fmed.2026.1779531)
10 Feb | 2026 A single-step radiolabeling strategy for PET, SPECT, and therapeutic radionuclides using nanoparticles as a universal chelator. Herraiz, A, Rodríguez-San-Pedro, A, Casquero-Veiga, M, Cossío, U, Arias-Ramos, N , Gutiérrez, L, Romero-Sanz, E, Luján-Rodríguez, VM, Cerón, C, Oteo, M, González-Paredes, A, López-Larrubia, P , Rosales, RTM, Cortes-Canteli, M , Morcillo, MA, Ruiz-Cabello, J, Pellico, J, Herranz, F. Npj Imaging - 4 (1) : 8 (PMID: 41667650) (doi:10.1038/s44303-026-00142-1)
10 Feb | 2026 Protective effect of melatonin against age-related ischemia-reperfusion injury is associated with the NLRP3 inflammasome pathway. Ben Jeddou, I, Berlana, Á , Rey, E, Ben Abdennebi, H, Almawi, WY, Omri, A, Valverde, ÁM , González-Rodriguez, Á , Zaouali, MA. J Physiol Biochem - 82 (1) : 9 (PMID: 41665836) (doi:10.1007/s13105-026-01145-7)
6 Feb | 2026 A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer. Centonze, A, Roura, AJ, Novillo-Font, M, Giordano, C, Hernando-Momblona, X, Llanses, M, Prats, P, Sevillano, M, Cabot, D, Novell, M, Pabst, G, Andersch, F, Cañellas-Socias, A, Zhang, C, Giakoumakis, NN, Sparks, H, Dunsby, C, Colombelli, J, Fernández-Barral, A , Sancho, E, Stephan-Otto Attolini, C, Muñoz, A , Barbachano, A , Palmer, HG , Martínez-Quintanilla, J, Zuber, J, Blaj, C, Quintana, E, Cortina, C, Marti-Renom, MA, Batlle, E. Cancer Discov - 16 (2) : 320-344 (PMID: 41128661) (doi:10.1158/2159-8290.CD-25-0679)
4 Feb | 2026 VCAN Is Essential for ERK5-Driven Tumorigenesis in Soft Tissue Sarcoma. Jiménez-Suárez, J, Cimas, FJ, Paricio, JJ, Belandia, B , Berrouayel, Y , Arconada-Luque, E, Matilla-Almazán, S, Soffientini, C, Percio, S, Redondo-García, S, García-Flores, N, Garnés-García, C, Fernández-Aroca, P, Martínez-Gómez, JJ, Fernández-Aramburo, A, Nam-Cha, SH, Rovida, E, Pandiella, A, Esparís-Ogando, A, Pasquali, S, Rodríguez-Manzaneque, JC, Del Peso, L , Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . Int J Biol Sci - 22 (5) : 2452-2468 (PMID: 41800245) (doi:10.7150/ijbs.121402)
3 Feb | 2026 Bioinformatic Analyses of the Ataxin-2 Family Since Algae Emphasize Its Small Isoforms, Large Chimerisms, and the Importance of Human Exon 1B as Target of Therapies to Prevent Neurodegeneration. Auburger, GWJ, Key, J, Gispert, S, Lastres-Becker, I , Almaguer-Mederos, LE, Bassa, C, Auburger, A, Auburger, G, Arsovic, A, Deller, T, Sen, NE. Int J Mol Sci - 27 (3) (PMID: 41683920) (doi:10.3390/ijms27031499)
28 Jan | 2026 A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages. Dunphy, G, Adán-Barrientos, I, Fernández-Delgado, I, Villarroya-Beltri, C, Heras-Murillo, I, Moya-Ruiz, E, Sánchez-Álvarez, M , Jarit-Cabanillas, A, Del Pozo, MA, Guerra, S, Sánchez-Madrid, F, Sancho, D. Immunity (PMID: 41610845) (doi:10.1016/j.immuni.2025.12.010)
23 Jan | 2026 The inhibition of Il1β synthesis mediated by a novel pyridine-sulfonamide compound protects against the progression of metabolic dysfunction-associated steatotic liver disease. Berlana, Á , Rey, E, Fresno-Ventura, E , Gomez-Gutierrez, P, Vega, M, García-Monzón, C, González-Rodríguez, Á . Biomed Pharmacother - 195 : 119052 (PMID: 41579710) (doi:10.1016/j.biopha.2026.119052)
16 Jan | 2026 PPARβ/δ contributes to the antidiabetic effect and the increase in GDF15 caused by metformin. Jurado-Aguilar, J, Barroso, E, Rada, P , Peyman, M, Rostami, A, Balsinde, J, Valverde, ÁM , Wahli, W, Palomer, X, Vázquez-Carrera, M. Acta Pharmacol Sin (PMID: 41545750) (doi:10.1038/s41401-025-01705-5)
13 Jan | 2026 Modulation of the Receptor Tyrosine Kinase TIE2/Tek Pathway by NRF2 Activation in Neurovascular Endothelial Cells. Cazalla, E , García-Yagüe, ÁJ , Pajares, M , Jiménez-Villegas, J , Escoll, M , Rojo, AI , Cuadrado, A . Int J Mol Sci - 27 (2) (PMID: 41596422) (doi:10.3390/ijms27020770)
13 Jan | 2026 NRF2 AT THE CROSSROADS OF PARKINSON'S DISEASE AND AGING: MECHANISTIC INSIGHTS AND TRANSLATIONAL PERSPECTIVES. Áj, GY , N, E, Dinkova-Kostova, AT, Ai, R , Pg, S, A, D, V, T, van Goor, H, Lastres-Becker, I . Free Radic Biol Med (PMID: 41539374) (doi:10.1016/j.freeradbiomed.2026.01.023)
7 Jan | 2026 Enhancing TFEA.ChIP with ENCODE regulatory maps for generalizable transcription factor enrichment. Berrouayel, Y , Del Peso, L . Brief Bioinform - 27 (1) (PMID: 41527853) (doi:10.1093/bib/bbaf715)
6 Jan | 2026 Uncovering the Role of Thrombospodin-1 and Occludin as Potential Prognostic and Diagnostic Biomarkers in Traumatic Brain Injury. Decouty-Pérez, C, Valencia, I, Alvarez-Rubal, M, Martínez-Cuevas, E, Farré-Alins, V, Calzada, MJ, Penalba, A, Montaner, J, Rodríguez de Cía, J, Taravilla-Loma, M, Hernández-García, BJ, Fuertes-Yebra, E, González-Rodríguez, Á , Lopez-Rodriguez, AB, Egea, J. Int J Mol Sci - 27 (2) (PMID: 41596222) (doi:10.3390/ijms27020571)
5 Jan | 2026 De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function. Bessler, N, Wezenaar, AKL, Ariese, HCR, Honhoff, C, Dommann, N, Wehrens, EJ, Ruiz Moreno, C, van den Broek, TJM, Collot, RVU, Kloosterman, DJ, Keramati, F, Roosen, M, de Blank, S, van Vliet, E, Barrera Román, M, Gatti, LCDE, Ertürk, A, Kuball, J, Sebestyén, Z, Kool, M, Patrizi, S, Miele, E, Künkele, A, Kranendonk, MEG, Cornel, AM, Nierkens, S, Mayer, C, Stunnenberg, HG, Alemany, A, Alieva, M , Rios, AC. Nat Cancer (PMID: 41492091) (doi:10.1038/s43018-025-01084-0)
5 Jan | 2026 GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model. Silva-Llanes, I , Smith, LA , Abdelkader-Guillén, A , Jiménez-Villegas, J , Sarrió, D , Moreno-Bueno, G , Lastres-Becker, I . J Biomed Sci - 33 (1) : 6 (PMID: 41486173) (doi:10.1186/s12929-025-01210-1)
2 Jan | 2026 Assessing Amplification Quality and Bias in MDA Methods Through Comparative Analysis of Short-Read Sequencing. Lozano-Escobar, ED , Mateo-Cáceres, V , Mayoral-Campos, C , Redrejo-Rodríguez, M . Methods Mol Biol - 3003 : 131-148 (PMID: 41478953) (doi:10.1007/978-1-0716-5060-8_10)