7 Aug | 2026 A clinical and experimental investigation of liraglutide effects on the brain-kidney axis. Greenwood, MP, Alotaibi, MI, Bárez-López, S , Cantley, NWP, Merritt, S, Tatovic, D, Murphy, D. Sci Adv - 12 (32) : eaef4951 (PMID: 42555711) (doi:10.1126/sciadv.aef4951)
4 Apr | 2025 Evaluation of the hepatic and subcutaneous adipose tissue effects of triiodothyronine treatment in an animal model of metabolic syndrome. Borges-Canha, M, Leite, AR, Conceição, G, Vale, C, Von-Hafe, M, Martins, D, Miranda-Silva, D, Sousa-Mendes, C, Chaves, J, Lourenço, IM, Grijota-Martínez, C , Bárez-López, S , Miranda, IM, Leite-Moreira, A, Falcão-Pires, I, Neves, JS. Obes Res Clin Pract (PMID: 40187955) (doi:10.1016/j.orcp.2025.04.001)
1 Jan | 2025 A Sensitive Radioimmunoassay for T3 and T4 Determinations in Plasma and Tissues. Montero-Pedrazuela, A , Grijota-Martínez, C , Guadaño-Ferraz, A , Bárez-López, S . Methods Mol Biol - 2876 : 37-59 (PMID: 39579307) (doi:10.1007/978-1-0716-4252-8_3)
1 Aug | 2024 Defective thyroid hormone transport to the brain leads to astroglial alterations. Guillén-Yunta, M , García-Aldea, Á , Valcárcel-Hernández, V , Sanz-Bógalo, A , Muñoz-Moreno, E, Matheus, MG, Grijota-Martínez, C , Montero-Pedrazuela, A , Guadaño-Ferraz, A , Bárez-López, S . Neurobiol Dis (PMID: 39097035) (doi:10.1016/j.nbd.2024.106621)
1 Feb | 2024 Insights on the role of thyroid hormone transport in neurosensory organs and implication for Allan-Herndon-Dudley syndrome. García-Aldea, Á , Guillén-Yunta, M , Valcárcel-Hernández, V , Montero-Pedrazuela, A , Guadaño-Ferraz, A , Bárez-López, S . Eur Thyroid J (PMID: 38417253) (doi:10.1530/ETJ-23-0241)
2 Jun | 2023 Isoflurane rapidly modifies synaptic and cytoskeletal phosphoproteomes of the supraoptic nucleus of the hypothalamus and the cortex. Bárez-López, S , Gadd, GJ, Pauža, AG, Murphy, D, Greenwood, MP. Neuroendocrinology (PMID: 37271138) (doi:10.1159/000531352)
26 May | 2023 Translational and Posttranslational Dynamics in a Model Peptidergic System. Bárez-López, S , Mecawi, AS, Bryan, N, Pauža, AG, Duque, VJ, Gillard, BT, Murphy, D, Greenwood, MP. Mol Cell Proteomics - 22 (5) : 100544 (PMID: 37030596) (doi:10.1016/j.mcpro.2023.100544)
4 May | 2023 Effects of Triiodothyronine Treatment in an Animal Model of Heart Failure with Preserved Ejection Fraction. Neves, JS, Leite, AR, Conceição, G, Gonçalves, A, Borges-Canha, M, Vale, C, Von-Hafe, M, Martins, D, Miranda-Silva, D, Leite, S, Rocha-Oliveira, E, Sousa-Mendes, C, Chaves, J, Lourenço, IM, Grijota-Martínez, C , Bárez-López, S , Miranda, IM, Almeida-Coelho, J, Vasques-Nóvoa, F, Carvalho, D, Lourenço, A, Falcão-Pires, I, Leite-Moreira, A. Thyroid (PMID: 37140469) (doi:10.1089/thy.2022.0717)
1 Apr | 2023 Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release. Greenwood, MP, Greenwood, M, Bárez-López, S , Hawkins, JW, Short, K, Tatovic, D, Murphy, D. Mol Metab - 70 : 101692 (PMID: 36773648) (doi:10.1016/j.molmet.2023.101692)
15 Feb | 2023 Maternal administration of the CNS-selective sobetirome prodrug Sob-AM2 exerts thyromimetic effects in murine MCT8-deficient fetuses. Valcárcel Hernández, V , Guillén Yunta, M , Scanlan, T, Bárez-López, S , Guadaño-Ferraz, A . Thyroid (PMID: 36792926) (doi:10.1089/thy.2022.0612)
14 Feb | 2023 Imaging the Hypothalamo-Neurohypophysial System. Bárez-López, S , Scanlon, L, Murphy, D, Greenwood, MP. Neuroendocrinology - 113 (2) : 168-178 (PMID: 34438401) (doi:10.1159/000519233)
17 Jan | 2023 Intracerebroventricular High Doses of 3,3',5-Triiodothyroacetic Acid at Juvenile Stages Improve Peripheral Hyperthyroidism and Mediate Thyromimetic Effects in Limited Brain Regions in a Mouse Model of Monocarboxylate Transporter 8 Deficiency. Grijota-Martínez, C , Montero-Pedrazuela, A , Hidalgo-Álvarez, J , Bárez-López, S , Guadaño-Ferraz, A . Thyroid (PMID: 36565029) (doi:10.1089/thy.2022.0562)
12 Oct | 2022 A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations. Valcárcel-Hernández, V , Guillén-Yunta, M , Bueno-Arribas, M , Montero-Pedrazuela, A , Grijota-Martínez, C , Markossian, S, García-Aldea, Á , Flamant, F, Bárez-López, S , Guadaño-Ferraz, A . Neurobiol Dis (PMID: 36243247) (doi:10.1016/j.nbd.2022.105896)
20 Jan | 2022 Transcriptional and Post-Transcriptional Regulation of Oxytocin and Vasopressin Gene Expression by CREB3L1 and CAPRIN2. Bárez-López, S , Konopacka, A, Cross, SJ, Greenwood, M, Skarveli, M, Murphy, D, Greenwood, MP. Neuroendocrinology - 112 (11) : 1058-1077 (PMID: 35051932) (doi:10.1159/000522088)
24 Nov | 2021 Deficient thyroid hormone transport to the brain leads to impairments in axonal caliber and oligodendroglial development. Valcárcel-Hernández, V , López-Espíndola, D , Guillén-Yunta, M , García-Aldea, Á , de Toledo-Soler, IL , Bárez-López, S , Guadaño-Ferraz, A . Neurobiol Dis (PMID: 34838669) (doi:10.1016/j.nbd.2021.105567)
20 Jul | 2020 Intranasal delivery of Thyroid hormones in MCT8 deficiency. Grijota-Martínez, C , Bárez-López, S , Ausó, E , Refetoff, S , Frey, WH, Guadaño-Ferraz, A . PLoS ONE - 15 (7) : e0236113 (PMID: 32687511) (doi:10.1371/journal.pone.0236113)
28 Apr | 2020 MCT8 Deficiency: The Road to Therapies for a Rare Disease. Grijota-Martínez, C , Bárez-López, S , Gómez-Andrés, D, Guadaño-Ferraz, A . Front Neurosci - 14 : 380 (PMID: 32410949) (doi:10.3389/fnins.2020.00380)
6 Dec | 2019 Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8. Bárez-López, S , Grijota-Martínez, C , Liao, XH, Refetoff, S , Guadaño-Ferraz, A . PLoS ONE - 14 (12) : e0226017 (PMID: 31809508) (doi:10.1371/journal.pone.0226017)
30 Jul | 2019 Adult mice lacking Mct8 and Dio2 proteins present alterations in peripheral thyroid hormone levels and severe brain and motor skill impairments. Bárez-López, S , Grijota-Martínez, C , Ausó, E , Fernández-de Frutos, M, Montero-Pedrazuela, A , Guadaño-Ferraz, A . Thyroid (PMID: 31359845) (doi:10.1089/thy.2019.0068)
30 May | 2018 Sobetirome and its amide prodrug Sob-AM2 exert thyromimetic actions in Mct8-deficient brain. Bárez-López, S , Hartley, MD, Grijota-Martínez, C , Scanlan, T, Guadaño-Ferraz, A . Thyroid (PMID: 29845892) (doi:10.1089/thy.2018.0008)
1 May | 2018 Thyroid Hormone Economy in the Perinatal Mouse Brain: Implications for Cerebral Cortex Development. Bárez-López, S , Obregon, MJ , Bernal, J , Guadaño-Ferraz, A . Cereb. Cortex - 28 (5) : 1783-1793 (PMID: 28407057) (doi:10.1093/cercor/bhx088)
1 Oct | 2017 Increased anxiety and fear memory in adult mice lacking type 2 deiodinase. Bárez-López, S , Montero-Pedrazuela, A , Bosch-García, D , Venero, C, Guadaño-Ferraz, A . Psychoneuroendocrinology - 84 : 51-60 (PMID: 28654773) (doi:10.1016/j.psyneuen.2017.06.013)
14 Aug | 2017 Thyroid Hormone Availability and Action during Brain Development in Rodents. Bárez-López, S , Guadaño-Ferraz, A . Front Cell Neurosci - 11 : 240 (PMID: 28855863) (doi:10.3389/fncel.2017.00240)
18 Jul | 2016 Adeno associated virus 9-based gene therapy delivers a functional monocarboxylate transporter 8 (MCT8) which improves thyroid hormone availability to brain of Mct8 deficient mice. Iwayama, H, Liao, XH, Braun, L, Bárez-López, S , Kaspar, B, Weiss, R, Dumitrescu, AM, Guadaño-Ferraz, A , Refetoff, S . Thyroid (PMID: 27432638) (doi:10.1089/thy.2016.0060)
1 May | 2016 Effect of Triiodothyroacetic Acid Treatment in Mct8 Deficiency: A Word of Caution. Bárez-López, S , Obregon, MJ , Martínez-de-Mena, R , Bernal, J , Guadaño-Ferraz, A , Morte, B . Thyroid - 26 (5) : 618-626 (PMID: 26701289) (doi:10.1089/thy.2015.0388)
1 Aug | 2014 Abnormal motor phenotype at adult stages in mice lacking type 2 deiodinase. Bárez-López, S , Bosch-García, D , Gómez-Andrés, D, Pulido-Valdeolivas, I, Montero-Pedrazuela, A , Obregon, MJ , Guadaño-Ferraz, A . PLoS ONE - 9 (8) : e103857 (PMID: 25083788) (doi:10.1371/journal.pone.0103857)