14 Mar | 2026 Perinatal liver sympathetic innervation governs body size. Bobo-Jimenez, V, Gomila, S, Lapresa, R, Agulla, J, Angibaud, J, Sanchez-Moran, I, Delgado-Esteban, M, González-Rodriguez, A , Fernández-Jaén, A, Ramos-Cabrer, P, Nägerl, UV, Bolaños, JP, Almeida, A. Commun Biol (PMID: 41826417) (doi:10.1038/s42003-026-09880-9)
10 Feb | 2026 Protective effect of melatonin against age-related ischemia-reperfusion injury is associated with the NLRP3 inflammasome pathway. Ben Jeddou, I, Berlana, Á , Rey, E, Ben Abdennebi, H, Almawi, WY, Omri, A, Valverde, ÁM , González-Rodriguez, Á , Zaouali, MA. J Physiol Biochem - 82 (1) : 9 (PMID: 41665836) (doi:10.1007/s13105-026-01145-7)
23 Jan | 2026 The inhibition of Il1β synthesis mediated by a novel pyridine-sulfonamide compound protects against the progression of metabolic dysfunction-associated steatotic liver disease. Berlana, Á , Rey, E, Fresno-Ventura, E , Gomez-Gutierrez, P, Vega, M, García-Monzón, C, González-Rodríguez, Á . Biomed Pharmacother - 195 : 119052 (PMID: 41579710) (doi:10.1016/j.biopha.2026.119052)
6 Jan | 2026 Uncovering the Role of Thrombospodin-1 and Occludin as Potential Prognostic and Diagnostic Biomarkers in Traumatic Brain Injury. Decouty-Pérez, C, Valencia, I, Alvarez-Rubal, M, Martínez-Cuevas, E, Farré-Alins, V, Calzada, MJ, Penalba, A, Montaner, J, Rodríguez de Cía, J, Taravilla-Loma, M, Hernández-García, BJ, Fuertes-Yebra, E, González-Rodríguez, Á , Lopez-Rodriguez, AB, Egea, J. Int J Mol Sci - 27 (2) (PMID: 41596222) (doi:10.3390/ijms27020571)
20 Nov | 2025 Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response. González-Corralejo, C, García-Sáez, J, Figueroa-Fuentes, M, Addante, A, Roncero, C, Lazcanoiturburu, N, Pacheco, B, Sanz, J, Gato, C, Fernández-Calderón, E, López, MO, González-Rodríguez, Á , Porras, A, Maina, F, Fabregat, I, Herrera, B, Sánchez, A. FEBS J (PMID: 41264321) (doi:10.1111/febs.70315)
19 Nov | 2025 Validation of BMP8A fibrosis score to identify patients with metabolic dysfunction-associated steatohepatitis with advanced liver fibrosis. Isaza, SC, Fernández-García, CE, Rojo, D, Iruzubieta, P, Ampuero, J, Aller, R, Campo, RV, Izquierdo-Sánchez, L, Fuertes-Yebra, E, Marañón, P, Banales, JM, Pagés, L, Jiménez-González, C, Cía, JR, Olaizola, I, Gómez-Camarero, J, Arroyo-Lopez, V, Romero-Gómez, M, Crespo, J, Pericàs, JM, García-Monzón, C, González-Rodríguez, Á , , . Biomark Res - 13 (1) : 149 (PMID: 41257923) (doi:10.1186/s40364-025-00862-3)
7 Aug | 2025 Normalization of Oxygen Levels Induces a Metabolic Reprogramming in Livers Exposed to Intermittent Hypoxia Mimicking Obstructive Sleep Apnea. Hernández-García, MÁ, Aldave-Orzáiz, B, Fernández-García, CE, Fuertes-Yebra, E, Rey, E, Berlana, Á , Farré, R, García-Monzón, C, Almendros, I, Landete, P, González-Rodríguez, Á . Antioxidants (Basel) - 14 (8) (PMID: 40867867) (doi:10.3390/antiox14080971)
21 Feb | 2025 Assessment of skeletal muscle alterations and circulating myokines in metabolic dysfunction-associated steatotic liver disease: A cross-sectional study. Real Martinez, Y, Fernandez-Garcia, CE, Fuertes-Yebra, E, Calvo Soto, M, Berlana, A, Barrios, V, Caldas, M, Gonzalez Moreno, L, Garcia-Buey, L, Molina Baena, B, Sampedro-Nuñez, M, Beceiro, MJ, García-Monzón, C, González-Rodríguez, Á . World J Gastroenterol - 31 (7) : 100039 (PMID: 39991673) (doi:10.3748/wjg.v31.i7.100039)
19 Jan | 2025 BMP6 participates in the molecular mechanisms involved in APAP hepatotoxicity. Marañón, P, Isaza, SC, Rey, E, Rada, P , García-García, Y, Dear, JW, García-Monzón, C, Valverde, ÁM , Egea, J, González-Rodríguez, Á . Arch Toxicol (PMID: 39827450) (doi:10.1007/s00204-024-03954-5)
12 Oct | 2024 Protein Kinase D2 modulates hepatic insulin sensitivity in male mice. Rada, P , Carceller-López, E , Hitos, AB , Gómez-Santos, B, Fernández-Hernández, C, Rey, E, Pose-Utrilla, J , García-Monzón, C, González-Rodríguez, Á , Sabio, G, García, A, Aspichueta, P, Iglesias, T , Valverde, ÁM . Mol Metab (PMID: 39401614) (doi:10.1016/j.molmet.2024.102045)
28 Jun | 2024 Potential protective role of let-7d-5p in atherosclerosis progression reducing the inflammatory pathway regulated by NF-κB and vascular smooth muscle cells proliferation. Aroca-Esteban, J, Souza-Neto, FV, Aguilar-Latorre, C, Tribaldo-Torralbo, A, González-López, P, Ruiz-Simón, R, Álvarez-Villareal, M, Ballesteros, S, de Ceniga, MV, Landete, P, González-Rodríguez, Á , Martín-Ventura, JL, de Las Heras, N, Escribano, Ó, Gómez-Hernández, A. Biochim Biophys Acta Mol Basis Dis (PMID: 38945455) (doi:10.1016/j.bbadis.2024.167327)
18 Jun | 2024 Fibroblast growth factor 21 is a hepatokine involved in MASLD progression. Gallego-Durán, R, Ampuero, J, Maya-Miles, D, Pastor-Ramírez, H, Montero-Vallejo, R, Rivera-Esteban, J, Álvarez-Amor, L, Pareja, MJ, Rico, MC, Millán, R, Robles-Frías, MJ, Aller, R, Rojas, Á, Muñoz-Hernández, R, Gil-Gómez, A, Gato, S, García-Lozano, M, Arias-Loste, MT, Abad, J, Calleja, JL, Andrade, RJ, Crespo, J, González-Rodríguez, Á , García-Monzón, C, Andreola, F, Pericás, JM, Jalan, R, Martín-Bermudo, F, Romero-Gómez, M. United European Gastroenterol J (PMID: 38894596) (doi:10.1002/ueg2.12534)
7 Jun | 2024 Beneficial effects of hepatic cyclooxygenase-2 expression against cholestatic injury after common bile duct ligation in mice. Brea, R , Casanova, N , Alvarez-Lucena, C , Fuertes-Agudo, M, Luque-Tevar, M, Cucarella, C, Capitani, MC, Marinochi, MV, Fusini, ME, Lahoz, A, Nogueroles, ML, Fraile, J , Ronco, MT, Boscá, L , González-Rodríguez, Á , García-Monzón, C, Martín-Sanz, P , Casado, M, Francés, DE . Liver Int (PMID: 38847511) (doi:10.1111/liv.16004)
15 Feb | 2024 Inhibition of ALK3-mediated signalling pathway protects against acetaminophen-induced liver injury. Marañón, P, Rey, E, Isaza, SC, Wu, H, Rada, P , Choya-Foces, C, Martínez-Ruiz, A, Martín, MÁ, Ramos, S, García-Monzón, C, Cubero, FJ, Valverde, ÁM , González-Rodríguez, Á . Redox Biol - 71 : 103088 (PMID: 38401290) (doi:10.1016/j.redox.2024.103088)
1 Feb | 2024 Hospital-based screening outperforms primary care screening as a means of achieving hepatitis C virus micro-elimination. Fernández-García, CE, Gallego-Galiana, J, Solís-Muñoz, PA, Del Pozo-Maroto, E, Domínguez-Alcón, L, Tobar-Izquierdo, M, Sáez, A, Rodríguez de Cía, J, Magaña-Sánchez, A, Real-Martínez, Y, García-Buey, L, González-Moreno, L, Caldas-Álvarez, M, Cardeñoso-Domingo, LM, González-Gamarra, A, Salvador-Calvo, A, González-Rodríguez, Á , García-Monzón, C. Infect Dis Now (PMID: 38309646) (doi:10.1016/j.idnow.2024.104855)
3 Jan | 2024 Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH. Fernández-Ginés, R , Encinar, JA, Escoll, M , Carnicero-Senabre, D , Jiménez-Villegas, J , García-Yagüe, ÁJ , González-Rodríguez, Á , Garcia-Martinez, I , M Valverde, Á , Rojo, AI , Cuadrado, A . Redox Biol - 69 : 103027 (PMID: 38184999) (doi:10.1016/j.redox.2024.103027)
1 May | 2023 Editorial: mitochondrial respiratory chain activity-a potential link with disease severity and treatment response in alcoholic hepatitis. Authors' reply. Solís-Muñoz, P, de la Flor-Robledo, M, Fernández-García, CE, González-Rodríguez, Á , García-Monzón, C. Aliment Pharmacol Ther - 57 (10) : 1159-1160 (PMID: 37094312) (doi:10.1111/apt.17469)
27 Apr | 2023 Circulating bone morphogenetic protein 8A is a novel biomarker to predict advanced liver fibrosis. Marañón, P, Isaza, SC, Fernández-García, CE, Rey, E, Gallego-Durán, R, Montero-Vallejo, R, de Cía, JR, Ampuero, J, Valverde, ÁM , Romero-Gómez, M, García-Monzón, C, González-Rodríguez, Á . Biomark Res - 11 (1) : 46 (PMID: 37106416) (doi:10.1186/s40364-023-00489-2)
21 Mar | 2023 Sleep apnea-COPD overlap syndrome is associated with larger left carotid atherosclerotic plaques. Landete, P, Fernández-García, CE, Muñoz, JM, Friera, A, Ancochea, J, González-Rodríguez, Á , García-Monzón, C. Front Cardiovasc Med - 10 : 1104377 (PMID: 37025690) (doi:10.3389/fcvm.2023.1104377)
2 Mar | 2023 Mitochondrial respiratory chain activity is associated with severity, corticosteroid response and prognosis of alcoholic hepatitis. Solís-Muñoz, P, de la Flor-Robledo, M, García-Ruíz, I, Fernández-García, CE, González-Rodríguez, Á , Shah, N, Bataller, R, Heneghan, M, García-Monzón, C, Solís-Herruzo, JA. Aliment Pharmacol Ther (PMID: 36864659) (doi:10.1111/apt.17434)
9 Jun | 2022 Ptpn1 deletion protects oval cells against lipoapoptosis by favoring lipid droplet formation and dynamics. Barahona, I , Rada, P , Calero-Pérez, S , Grillo-Risco, R, Pereira, L, Soler-Vázquez, MC, LaIglesia, LM, Moreno-Aliaga, MJ, Herrero, L, Serra, D, García-Monzon, C, González-Rodriguez, Á , Balsinde, J, García-García, F, Valdecantos, MP , Valverde, ÁM . Cell Death Differ (PMID: 35681014) (doi:10.1038/s41418-022-01023-x)
25 May | 2022 Bone morphogenetic protein 2 is a new molecular target linked to non-alcoholic fatty liver disease with potential value as non-invasive screening tool. Marañón, P, Fernández-García, CE, Isaza, SC, Rey, E, Gallego-Durán, R, Montero-Vallejo, R, de Cía, JR, Ampuero, J, Romero-Gómez, M, García-Monzón, C, González-Rodríguez, Á . Biomark Res - 10 (1) : 35 (PMID: 35614516) (doi:10.1186/s40364-022-00383-3)
19 Oct | 2020 Defective liver glycogen autophagy related to hyperinsulinemia in intrauterine growth-restricted newborn wistar rats. de Toro-Martín, J, Fernández-Marcelo, T, González-Rodríguez, Á , Escrivá, F, Valverde, ÁM , Álvarez, C, Fernández-Millán, E. Sci Rep - 10 (1) : 17651 (PMID: 33077861) (doi:10.1038/s41598-020-74702-9)
25 Sep | 2020 Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver? Rada, P , González-Rodríguez, Á , García-Monzón, C, Valverde, ÁM . Cell Death Dis - 11 (9) : 802 (PMID: 32978374) (doi:10.1038/s41419-020-03003-w)
16 Jul | 2019 Insulin receptor substrate 2 (IRS2) deficiency delays liver fibrosis associated with cholestatic injury. Villar-Lorenzo, A , Rada, P , Rey, E, Marañón, P, Arroba, AI , Santamaría, B , Sáiz, J, Rupérez, FJ, Barbas, C, García-Monzón, C, Valverde, ÁM , González-Rodríguez, Á . Dis Model Mech - 12 (7) (PMID: 31262748) (doi:10.1242/dmm.038810)
24 Sep | 2018 Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans. Cruces-Sande, M, Vila-Bedmar, R, Arcones, AC, González-Rodríguez, Á , Rada, P , Gutiérrez-de-Juan, V, Vargas-Castrillón, J, Iruzubieta, P, Sánchez-González, C, Formentini, L, Crespo, J, García-Monzón, C, Martínez-Chantar, ML, Valverde, ÁM , Mayor, F, Murga, C. Biochim Biophys Acta Mol Basis Dis (PMID: 30261289) (doi:10.1016/j.bbadis.2018.09.027)
1 Jan | 2018 Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis. González-Rodríguez, Á , Valdecantos, MP , Rada, P , Addante, A, Barahona, I , Rey, E, Pardo, V , Ruiz, L , Laiglesia, LM, Moreno-Aliaga, MJ, García-Monzón, C, Sánchez, A, Valverde, ÁM . Mol Metab - 7 : 132-146 (PMID: 29126873) (doi:10.1016/j.molmet.2017.10.008)
1 Mar | 2017 A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice. Valdecantos, MP , Pardo, V , Ruiz, L , Castro-Sánchez, L, Lanzón, B, Fernández-Millán, E, García-Monzón, C, Arroba, AI , González-Rodríguez, Á , Escrivá, F, Álvarez, C, Rupérez, FJ, Barbas, C, Konkar, A, Naylor, J, Hornigold, D, Santos, AD, Bednarek, M, Grimsby, J, Rondinone, CM, Valverde, ÁM . Hepatology - 65 (3) : 950-968 (PMID: 27880981) (doi:10.1002/hep.28962)
15 Dec | 2016 Friedelane-type triterpenoids as selective anti-inflammatory agents by regulation of differential signaling pathways in LPS-stimulated macrophages. Villar-Lorenzo, A , Ardiles, AE, Arroba, AI , Hernández-Jiménez, E, Pardo, V , López-Collazo, E, Jiménez, IA, Bazzocchi, IL, González-Rodríguez, Á , Valverde, ÁM . Toxicol. Appl. Pharmacol. - 313 : 57-67 (PMID: 27751938) (doi:10.1016/j.taap.2016.10.004)
1 Oct | 2016 Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency. Zarei, M, Barroso, E, Leiva, R, Barniol-Xicota, M, Pujol, E, Escolano, C, Vázquez, S, Palomer, X, Pardo, V , González-Rodríguez, Á , Valverde, ÁM , Quesada-López, T, Villarroya, F, Wahli, W, Vázquez-Carrera, M. Diabetes - 65 (10) : 3185-3199 (PMID: 27486236) (doi:10.2337/db16-0155)
1 May | 2016 Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model. Baquedano, E, Burgos-Ramos, E, Canelles, S, González-Rodríguez, A , Chowen, JA, Argente, J, Barrios, V, Valverde, AM , Frago, LM . Dis Model Mech - 9 (5) : 573-583 (PMID: 27013528) (doi:10.1242/dmm.023515)
1 Feb | 2016 Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis. López-Luque, J, Caballero-Díaz, D, Martinez-Palacián, A, Roncero, C, Moreno-Càceres, J, García-Bravo, M, Grueso, E, Fernández, A, Crosas-Molist, E, García-Álvaro, M, Addante, A, Bertran, E, Valverde, AM , González-Rodríguez, Á , Herrera, B, Montoliu, L, Serrano, T, Segovia, JC, Fernández, M , Ramos, E, Sánchez, A, Fabregat, I. Hepatology - 63 (2) : 604-619 (PMID: 26313466) (doi:10.1002/hep.28134)
31 Dec | 2015 IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes. Santamaria, B , Marquez, E, Lay, A, Carew, RM, González-Rodríguez, Á , Welsh, GI, Ni, L, Hale, LJ, Ortiz, A, Saleem, MA, Brazil, DP, Coward, RJ, Valverde, ÁM . Biochim. Biophys. Acta - 1853 (12) : 3224-3234 (PMID: 26384875) (doi:10.1016/j.bbamcr.2015.09.020)
21 Oct | 2015 RNA Interference as a Therapeutic Strategy for the Treatment of Liver Diseases. Gonzalez-Rodriguez, A , Valverde, AM . Curr. Pharm. Des. - 21 (31) : 4574-4586 (PMID: 26486144)
4 Aug | 2015 Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner. González-Rodríguez, Á , Santamaría, B , Mas-Gutierrez, JA, Rada, P , Fernández-Millán, E, Pardo, V , Álvarez, C, Cuadrado, A , Ros, M, Serrano, M, Valverde, ÁM . Mol Nutr Food Res - 59 (8) : 1431-1442 (PMID: 25808216) (doi:10.1002/mnfr.201400933)
1 May | 2015 Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity, and insulin resistance. Francés, DE , Motiño, O , Agrá, N, González-Rodríguez, Á , Fernández-Álvarez, A, Cucarella, C, Mayoral, R , Castro-Sánchez, L, García-Casarrubios, E , Boscá, L , Carnovale, CE, Casado, M, Valverde, ÁM , Martín-Sanz, P . Diabetes - 64 (5) : 1522-1531 (PMID: 25422106) (doi:10.2337/db14-0979)
3 Apr | 2015 Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection. Pardo, V , González-Rodríguez, Á , Muntané, J, Kozma, SC, Valverde, ÁM . Food Chem. Toxicol. (PMID: 25846498) (doi:10.1016/j.fct.2015.03.029)
19 Mar | 2015 Opposite Cross-Talk by Oleate and Palmitate on Insulin Signaling in Hepatocytes through Macrophage Activation. Pardo, V , Gonzalez-Rodriguez, A , Guijas, C, Balsinde, J, Valverde, AM . J. Biol. Chem. (PMID: 25792746) (doi:10.1074/jbc.M115.649483)
17 Oct | 2014 Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes. Mobasher, MA, de Toro-Martín, J, González-Rodríguez, Á , Ramos, S, Letzig, LG, James, LP, Muntané, J, Álvarez, C, Valverde, ÁM . J. Biol. Chem. - 289 (42) : 29406-29419 (PMID: 25204659) (doi:10.1074/jbc.M113.539189)
1 Sep | 2014 In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice. González-Rodríguez, Á , Reibert, B, Amann, T, Constien, R, Rondinone, CM, Valverde, ÁM . Dis Model Mech - 7 (9) : 1093-1100 (PMID: 24997191) (doi:10.1242/dmm.015537)
19 Jun | 2013 Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice. Arroba, AI , Revuelta-Cervantes, J , Menes, L, González-Rodríguez, Á , Pardo, V , de la Villa, P, Burks, DJ, Valverde, ÁM . Invest. Ophthalmol. Vis. Sci. - 54 (6) : 4215-4225 (PMID: 23702782) (doi:10.1167/iovs.12-11438)
24 May | 2013 Sterile inflammation in acetaminophen-induced liver injury is mediated by Cot/tpl2. Sanz-Garcia, C, Ferrer-Mayorga, G , González-Rodríguez, Á , Valverde, AM , Martín-Duce, A, Velasco-Martín, JP, Regadera, J, Fernández, M , Alemany, S . J. Biol. Chem. - 288 (21) : 15342-15351 (PMID: 23572518) (doi:10.1074/jbc.M112.439547)
7 Jan | 2013 Proapoptotic and survival signaling in the neuroretina at early stages of diabetic retinopathy. Valverde, AM , Miranda, S , García-Ramírez, M, González-Rodriguez, Á , Hernández, C, Simó, R. Mol. Vis. - 19 : 47-53 (PMID: 23335850)
1 Dec | 2012 Studies of naturally occurring friedelane triterpenoids as insulin sensitizers in the treatment type 2 diabetes mellitus. Ardiles, AE, González-Rodríguez, A , Núñez, MJ, Perestelo, NR, Pardo, V , Jiménez, IA, Valverde, AM , Bazzocchi, IL. Phytochemistry - 84 : 116-124 (PMID: 22925829) (doi:10.1016/j.phytochem.2012.07.025)
1 Jun | 2012 Beneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions. Miranda, S , González-Rodríguez, Á , García-Ramírez, M, Revuelta-Cervantes, J , Hernández, C, Simó, R, Valverde, ÁM . J. Cell. Physiol. - 227 (6) : 2352-2362 (PMID: 21826649) (doi:10.1002/jcp.22970)
4 May | 2012 Protein-tyrosine phosphatase 1B (PTP1B) deficiency confers resistance to transforming growth factor-β (TGF-β)-induced suppressor effects in hepatocytes. Ortiz, C, Caja, L, Bertran, E, Gonzalez-Rodriguez, Á , Valverde, ÁM , Fabregat, I, Sancho, P. J. Biol. Chem. - 287 (19) : 15263-15274 (PMID: 22427664) (doi:10.1074/jbc.M111.303958)
1 Apr | 2012 Essential role of protein tyrosine phosphatase 1B in obesity-induced inflammation and peripheral insulin resistance during aging. González-Rodríguez, A , Más-Gutierrez, JA, Mirasierra, M , Fernandez-Pérez, A , Lee, YJ, Ko, HJ, Kim, JK, Romanos, E, Carrascosa, JM, Ros, M, Vallejo, M , Rondinone, CM, Valverde, AM . Aging Cell - 11 (2) : 284-296 (PMID: 22221695) (doi:10.1111/j.1474-9726.2011.00786.x)
30 Mar | 2012 Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function. Murillo-Cuesta, S , Camarero, G , González-Rodríguez, A , De La Rosa, LR , Burks, DJ, Avendaño, C, Valverde, AM , Varela-Nieto, I . Mol. Med. - 18 : 260-269 (PMID: 22160220) (doi:10.2119/molmed.2011.00328)
1 Mar | 2012 Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/- mice. Burgos-Ramos, E, González-Rodríguez, A , Canelles, S, Baquedano, E, Frago, LM , Revuelta-Cervantes, J , Gómez-Ambrosi, J, Frühbeck, G, Chowen, JA, Argente, J, Valverde, AM , Barrios, V. Endocrinology - 153 (3) : 1129-1140 (PMID: 22210743) (doi:10.1210/en.2011-1278)
1 Jul | 2011 IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling. Valverde, AM , González-Rodríguez, A . Arch. Physiol. Biochem. - 117 (3) : 105-115 (PMID: 21401320) (doi:10.3109/13813455.2011.557386)
1 Apr | 2011 Protein Tyrosine Phosphatase 1B (PTP1B) deficiency accelerates hepatic regeneration in mice. Revuelta-Cervantes, J , Mayoral, R , Miranda, S , González-Rodríguez, A , Fernández, M , Martín-Sanz, P , Valverde, AM . Am. J. Pathol. - 178 (4) : 1591-1604 (PMID: 21406170) (doi:10.1016/j.ajpath.2010.12.020)
1 Jan | 2011 Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C. García-Monzón, C, Lo Iacono, O, Mayoral, R , González-Rodríguez, A , Miquilena-Colina, ME, Lozano-Rodríguez, T, García-Pozo, L, Vargas-Castrillón, J, Casado, M, Boscá, L , Valverde, AM , Martín-Sanz, P . J. Hepatol. - 54 (1) : 142-152 (PMID: 20888662) (doi:10.1016/j.jhep.2010.06.021)
1 Oct | 2010 PTP1B deficiency enhances liver growth during suckling by increasing the expression of insulin-like growth factor-I. Escrivá, F, González-Rodriguez, A , Fernández-Millán, E, Rondinone, CM, Alvarez, C, Valverde, AM . J. Cell. Physiol. - 225 (1) : 214-222 (PMID: 20506299) (doi:10.1002/jcp.22246)
1 Apr | 2010 Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli. Miranda, S , González-Rodríguez, A , Revuelta-Cervantes, J , Rondinone, CM, Valverde, AM . Cell. Signal. - 22 (4) : 645-659 (PMID: 20026400) (doi:10.1016/j.cellsig.2009.11.019)
30 Mar | 2010 Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice. González-Rodríguez, A , Mas Gutierrez, JA, Sanz-González, S, Ros, M, Burks, DJ, Valverde, AM . Diabetes - 59 (3) : 588-599 (PMID: 20028942) (doi:10.2337/db09-0796)
5 Feb | 2010 Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes: role in liver regeneration. Mayoral, R , Valverde, AM , Llorente Izquierdo, C , González-Rodríguez, A , Boscá, L , Martín-Sanz, P . J. Biol. Chem. - 285 (6) : 3633-3642 (PMID: 19966340) (doi:10.1074/jbc.M109.072900)
18 Jan | 2010 Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1. Fernandez-Marcos, PJ, Pantoja, C, Gonzalez-Rodriguez, A , Martin, N, Flores, JM, Valverde, AM , Hara, E, Serrano, M. PLoS ONE - 5 (1) : e8744 (PMID: 20090907) (doi:10.1371/journal.pone.0008744)
28 Jul | 2009 S6K1 deficiency protects against apoptosis in hepatocytes. González-Rodriguez, A , Alba, J, Zimmerman, V, Kozma, SC, Valverde, AM . Hepatology - 50 (1) : 216-229 (PMID: 19437488) (doi:10.1002/hep.22915)
8 Aug | 2008 PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes. González-Rodriguez, A , Nevado, C, Escrivá, F, Sesti, G, Rondinone, CM, Benito, M, Valverde, AM . Am. J. Physiol. Gastrointest. Liver Physiol. - 295 (2) : G338-47 (PMID: 18535291) (doi:10.1152/ajpgi.00514.2007)
27 Jul | 2007 Levels of protein tyrosine phosphatase 1B determine susceptibility to apoptosis in serum-deprived hepatocytes. González-Rodriguez, A , Escribano, O, Alba, J, Rondinone, CM, Benito, M, Valverde, AM . J. Cell. Physiol. - 212 (1) : 76-88 (PMID: 17323378) (doi:10.1002/jcp.21004)
27 Feb | 2007 Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes. Gonzalez-Rodriguez, A , Clampit, JE, Escribano, O, Benito, M, Rondinone, CM, Valverde, AM . Endocrinology - 148 (2) : 594-608 (PMID: 17068137) (doi:10.1210/en.2006-0644)