Neuroendocrine Pathology

Thyroid Hormones & Oxytocin: Keys to Brain and Mental Health

Mental health disorders are among the leading causes of disability worldwide, yet their biological underpinnings remain poorly understood. Hormones play a critical but often overlooked role in regulating brain function, emotional states, and resilience.

At the Neuroendocrine Pathology Lab, we study how thyroid hormones (THs) and oxytocin (OXT) interact to regulate neural circuits that control mood, stress, and social behaviour. By unravelling this hormonal cross-talk, we aim to:

  • Identify biomarkers of vulnerability: discover signatures that predict risk for mental health disorders.

  • Uncover therapeutic targets: reveal molecular and neural pathways that can be modulated to restore emotional balance.

  • Map brain circuits: chart how THs and OXT converge in key regions, such as the amygdala, to influence behaviour and mental well-being.

Our approaches:
We combine molecular biology, animal models, neural circuit mapping, and clinical collaborations. We integrate classical tools with cutting-edge approaches such as genetic models, viral tracing, chemogenetics, and transcriptomics to connect mechanisms with outcomes.

Our mission:

  • Predict and prevent mental health disorders through hormonal and neural biomarkers.

  • Develop innovative therapies targeting the TH–OXT axis.

  • Contribute to healthier brains and healthier lives.

We believe that understanding TH–OXT interactions is essential to unlocking new strategies for mental health.

Join us! Students, collaborators, and curious minds are welcome.

Group Coordinator

Adscribed Personnel