Puente-Santamaria, L.; Wasserman, W.W.; Del Peso, L. "TFEA.ChIP: a tool kit for transcription factor binding site enrichment analysis capitalizing on ChIP-seq datasets.". Bioinformatics. 35(24): 5339-5340. (2019). (PMID: 31347689).
Batie, M.; Del Peso, L.; Rocha, S. "Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms.". Biomedicines. 6(2): . (2018). (PMID: 29690561).
Tiana, M.; Villar, D.; Pérez-Guijarro, E.; Gómez-Maldonado, L.; Moltó, E.; Fernández-Miñán, A.; Gómez-Skarmeta, J.L.; Montoliu, L.; del Peso, L. "A role for insulator elements in the regulation of gene expression response to hypoxia.". Nucleic Acids Res.. 40(5): 1916-1927. (2012). (PMID: 22067454).
Conde, E.; Alegre, L.; Blanco-Sánchez, I.; Sáenz-Morales, D.; Aguado-Fraile, E.; Ponte, B.; Ramos, E.; Sáiz, A.; Jiménez, C.; Ordoñez, A.; López-Cabrera, M.; del Peso, L.; de Landázuri, M.O.; Liaño, F.; Selgas, R.; Sanchez-Tomero, J.A.; García-Bermejo, M.L. "Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival.". PLoS ONE. 7(3): e33258. (2012). (PMID: 22432008).
Fernández-Barral, A.; Orgaz, J.L.; Gomez, V.; del Peso, L.; Calzada, M.J.; Jiménez, B. "Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism.". PLoS ONE. 7(3): e32989. (2012). (PMID: 22457728).
Martinez-Poveda, B.; Gomez, V.; Alcaide-German, M.; Perruca, S.; Vazquez, S.; Alba, L.E.; Casanovas, O.; Garcia-Bermejo, M.L.; Peso, L.; Jimenez, B. "Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma.". Int. J. Oncol.. 39(3): 543-552. (2011). (PMID: 21667025).
Ortiz-Barahona, A.; Villar, D.; Pescador, N.; Amigo, J.; del Peso, L. "Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction.". Nucleic Acids Res.. 38(7): 2332-2345. (2010). (PMID: 20061373).
Pescador, N.; Villar, D.; Cifuentes, D.; Garcia-Rocha, M.; Ortiz-Barahona, A.; Vazquez, S.; Ordoñez, A.; Cuevas, Y.; Saez-Morales, D.; Garcia-Bermejo, M.L.; Landazuri, M.O.; Guinovart, J.; del Peso, L. "Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1.". PLoS ONE. 5(3): e9644. (2010). (PMID: 20300197).
Aceves-Luquero, C.I.; Agarwal, A.; Callejas-Valera, J.L.; Arias-González, L.; Esparís-Ogando, A.; del Peso Ovalle, L.; Bellón-Echeverria, I.; de la Cruz-Morcillo, M.A.; Galán Moya, E.M.; Moreno Gimeno, I.; Gómez, J.C.; Deininger, M.W.; Pandiella, A.; Sánchez Prieto, R. "ERK2, but not ERK1, mediates acquired and "de novo" resistance to imatinib mesylate: implication for CML therapy.". PLoS ONE. 4(7): e6124. (2009). (PMID: 19568437).
Alcaide-German, M.L.; Vara-Vega, A.; Garcia-Fernandez, L.F.; Landazuri, M.O.; del Peso, L. "A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery.". BMC Cell Biol.. 9(): 18. (2008). (PMID: 18402654).
Villar, D.; Vara-Vega, A.; Landázuri, M.O.; Del Peso, L. "Identification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains.". Biochem. J.. 408(2): 231-240. (2007). (PMID: 17725546).
Olmos, G.; Conde, I.; Arenas, I.; Del Peso, L.; Castellanos, C.; Landazuri, M.O.; Lucio-Cazana, J. "Accumulation of hypoxia-inducible factor-1alpha through a novel electrophilic, thiol antioxidant-sensitive mechanism.". Cell. Signal.. 19(10): 2098-2105. (2007). (PMID: 17658243).
Calzada, M.J.; del Peso, L. "Hypoxia-inducible factors and cancer.". Clin Transl Oncol. 9(5): 278-289. (2007). (PMID: 17525038).
Landázuri, M.O.; Vara-Vega, A.; Vitón, M.; Cuevas, Y.; del Peso, L. "Analysis of HIF-prolyl hydroxylases binding to substrates.". Biochem. Biophys. Res. Commun.. 351(2): 313-320. (2006). (PMID: 17069766).
Pescador, N.; Cuevas, Y.; Naranjo, S.; Alcaide, M.; Villar, D.; Landázuri, M.O.; Del Peso, L. "Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene.". Biochem J. 390(Pt 1): 189-197. (2005). (PMID: 15823097).
del Peso, L.; Castellanos, M.C.; Temes, E.; Martin-Puig, S.; Cuevas, Y.; Olmos, G.; Landazuri, M.O. "The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen.". J. Biol. Chem.. 278(49): 48690-48695. (2003). (PMID: 14506252).
Cuevas, Y.; Hernández-Alcoceba, R.; Aragones, J.; Naranjo-Suárez, S.; Castellanos, M.C.; Esteban, M.A.; Martín-Puig, S.; Landazuri, M.O.; del Peso, L. "Specific oncolytic effect of a new hypoxia-inducible factor-dependent replicative adenovirus on von Hippel-Lindau-defective renal cell carcinomas.". Cancer Res.. 63(20): 6877-6884. (2003). (PMID: 14583486).
Naranjo-Suárez, S.; Castellanos, M.C.; Alvarez-Tejado, M.; Vara, A.; Landázuri, M.O.; del Peso, L. "Down-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation.". J. Biol. Chem.. 278(34): 31895-31901. (2003). (PMID: 12805361).
Alvarez-Tejado, M.; Alfranca, A.; Aragonés, J.; Vara, A.; Landázuri, M.O.; del Peso, L. "Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.". J. Biol. Chem.. 277(16): 13508-13517. (2002). (PMID: 11815624).
Alvarez-Tejado, M.; Naranjo-Suarez, S.; Jiménez, C.; Carrera, A.C.; Landázuri, M.O.; del Peso, L. "Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis.". J. Biol. Chem.. 276(25): 22368-22374. (2001). (PMID: 11294857).
Inohara, N.; Koseki, T.; Lin, J.; del Peso, L.; Lucas, P.C.; Chen, F.F.; Ogura, Y.; Núñez, G. "An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways.". J. Biol. Chem.. 275(36): 27823-27831. (2000). (PMID: 10880512).
del Peso, L.; Gonzalez, V.M.; Inohara, N.; Ellis, R.E.; Núñez, G. "Disruption of the CED-9.CED-4 complex by EGL-1 is a critical step for programmed cell death in Caenorhabditis elegans.". J. Biol. Chem.. 275(35): 27205-27211. (2000). (PMID: 10846174).
Lucas, L.; del Peso, L.; Rodríguez, P.; Penalva, V.; Lacal, J.C. "Ras protein is involved in the physiological regulation of phospholipase D by platelet derived growth factor.". Oncogene. 19(3): 431-437. (2000). (PMID: 10656691).
del Peso, L.; González, V.M.; Hernández, R.; Barr, F.G.; Núñez, G. "Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt.". Oncogene. 18(51): 7328-7333. (1999). (PMID: 10602488).
Inohara, N.; Koseki, T.; del Peso, L.; Hu, Y.; Yee, C.; Chen, S.; Carrio, R.; Merino, J.; Liu, D.; Ni, J.; Núñez, G. "Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB.". J. Biol. Chem.. 274(21): 14560-14567. (1999). (PMID: 10329646).
del Peso, L.; González, V.M.; Núñez, G. "Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation.". J. Biol. Chem.. 273(50): 33495-33500. (1998). (PMID: 9837929).
Esteve, P.; Embade, N.; Perona, R.; Jiménez, B.; del Peso, L.; León, J.; Arends, M.; Miki, T.; Lacal, J.C. "Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway.". Oncogene. 17(14): 1855-1869. (1998). (PMID: 9778052).
Inohara, N.; del Peso, L.; Koseki, T.; Chen, S.; Núñez, G. "RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis.". J. Biol. Chem.. 273(20): 12296-12300. (1998). (PMID: 9575181).
del Peso, L.; González-García, M.; Page, C.; Herrera, R.; Nuñez, G. "Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.". Science. 278(5338): 687-689. (1997). (PMID: 9381178).
del Peso, L.; Lucas, L.; Esteve, P.; Lacal, J.C. "Activation of phospholipase D by growth factors and oncogenes in murine fibroblasts follow alternative but cross-talking pathways.". Biochem. J.. 322 ( Pt 2)(): 519-528. (1997). (PMID: 9065772).
del Peso, L.; Hernández, R.; Esteve, P.; Lacal, J.C. "Activation of phospholipase D by ras proteins is independent of protein kinase C.". J. Cell. Biochem.. 61(4): 599-608. (1996). (PMID: 8806084).
Esteve, P.; del Peso, L.; Lacal, J.C. "Induction of apoptosis by rho in NIH 3T3 cells requires two complementary signals. Ceramides function as a progression factor for apoptosis.". Oncogene. 11(12): 2657-2665. (1995). (PMID: 8545123).
Jiménez, B.; del Peso, L.; Montaner, S.; Esteve, P.; Lacal, J.C. "Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation.". J. Cell. Biochem.. 57(1): 141-149. (1995). (PMID: 7721953).
Carnero, A.; Cuadrado, A.; del Peso, L.; Lacal, J.C. "Activation of type D phospholipase by serum stimulation and ras-induced transformation in NIH3T3 cells.". Oncogene. 9(5): 1387-1395. (1994). (PMID: 8152799).
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