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PUBLICACIONES

 

 

spacerTrabajos Publicados por María del Carmen Grijota Martínez
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  1. Montero-Pedrazuela, A.; Grijota-Martínez, C.; Guadaño-Ferraz, A.; Bárez-López, S. "A Sensitive Radioimmunoassay for T3 and T4 Determinations in Plasma and Tissues.". Methods Mol Biol. 2876(): 37-59. (2025). (PMID: 39579307).
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  2. Borges-Canha, M.; Leite, A.R.; Conceição, G.; Vale, C.; Von-Hafe, M.; Martins, D.; Miranda-Silva, D.; Sousa-Mendes, C.; Chaves, J.; Lourenço, I.M.; Grijota-Martínez, C.; Bárez-López, S.; Miranda, I.M.; Leite-Moreira, A.; Falcão-Pires, I.; Neves, J.S. "Evaluation of the hepatic and subcutaneous adipose tissue effects of triiodothyronine treatment in an animal model of metabolic syndrome.". Obes Res Clin Pract. (): . (2025). (PMID: 40187955).
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  3. Guillén-Yunta, M.; García-Aldea, Á.; Valcárcel-Hernández, V.; Sanz-Bógalo, A.; Muñoz-Moreno, E.; Matheus, M.G.; Grijota-Martínez, C.; Montero-Pedrazuela, A.; Guadaño-Ferraz, A.; Bárez-López, S. "Defective thyroid hormone transport to the brain leads to astroglial alterations.". Neurobiol Dis. (): 106621. (2024). (PMID: 39097035).
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  4. Neves, J.S.; Leite, A.R.; Conceição, G.; Gonçalves, A.; Borges-Canha, M.; Vale, C.; Von-Hafe, M.; Martins, D.; Miranda-Silva, D.; Leite, S.; Rocha-Oliveira, E.; Sousa-Mendes, C.; Chaves, J.; Lourenço, I.M.; Grijota-Martínez, C.; Bárez-López, S.; Miranda, I.M.; Almeida-Coelho, J.; Vasques-Nóvoa, F.; Carvalho, D.; Lourenço, A.; Falcão-Pires, I.; Leite-Moreira, A. "Effects of Triiodothyronine Treatment in an Animal Model of Heart Failure with Preserved Ejection Fraction.". Thyroid. (): . (2023). (PMID: 37140469).
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  5. Grijota-Martínez, C.; Montero-Pedrazuela, A.; Hidalgo-Álvarez, J.; Bárez-López, S.; Guadaño-Ferraz, A. "Intracerebroventricular High Doses of 3,3',5-Triiodothyroacetic Acid at Juvenile Stages Improve Peripheral Hyperthyroidism and Mediate Thyromimetic Effects in Limited Brain Regions in a Mouse Model of Monocarboxylate Transporter 8 Deficiency.". Thyroid. (): . (2023). (PMID: 36565029).
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  6. Rial-Pensado, E.; Rivas-Limeres, V.; Grijota-Martínez, C.; Rodríguez-Díaz, A.; Capelli, V.; Barca-Mayo, O.; Nogueiras, R.; Mittag, J.; Diéguez, C.; López, M. "Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis.". Front Physiol. 13(): 1017381. (2022). (PMID: 36467699).
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  7. Valcárcel-Hernández, V.; Guillén-Yunta, M.; Bueno-Arribas, M.; Montero-Pedrazuela, A.; Grijota-Martínez, C.; Markossian, S.; García-Aldea, Á.; Flamant, F.; Bárez-López, S.; Guadaño-Ferraz, A. "A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations.". Neurobiol Dis. (): 105896. (2022). (PMID: 36243247).
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  8. Grijota-Martínez, C.; Bárez-López, S.; Ausó, E.; Refetoff, S.; Frey, W.H.; Guadaño-Ferraz, A. "Intranasal delivery of Thyroid hormones in MCT8 deficiency.". PLoS ONE. 15(7): e0236113. (2020). (PMID: 32687511).
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  9. Grijota-Martínez, C.; Bárez-López, S.; Gómez-Andrés, D.; Guadaño-Ferraz, A. "MCT8 Deficiency: The Road to Therapies for a Rare Disease.". Front Neurosci. 14(): 380. (2020). (PMID: 32410949).
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  10. Bárez-López, S.; Grijota-Martínez, C.; Liao, X.H.; Refetoff, S.; Guadaño-Ferraz, A. "Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8.". PLoS ONE. 14(12): e0226017. (2019). (PMID: 31809508).
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  11. Bárez-López, S.; Grijota-Martínez, C.; Ausó, E.; Fernández-de Frutos, M.; Montero-Pedrazuela, A.; Guadaño-Ferraz, A. "Adult mice lacking Mct8 and Dio2 proteins present alterations in peripheral thyroid hormone levels and severe brain and motor skill impairments.". Thyroid. (): . (2019). (PMID: 31359845).
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  12. Bárez-López, S.; Hartley, M.D.; Grijota-Martínez, C.; Scanlan, T.; Guadaño-Ferraz, A. "Sobetirome and its amide prodrug Sob-AM2 exert thyromimetic actions in Mct8-deficient brain.". Thyroid. (): . (2018). (PMID: 29845892).
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  13. Palomo-Guerrero, M.; Cosgaya, J.M.; Gella, A.; Casals, N.; Grijota-Martinez, C. "Uridine-5'-Triphosphate Partially Blocks Differentiation Signals and Favors a more Repair State in Cultured rat Schwann Cells.". Neuroscience. 372(): 255-265. (2018). (PMID: 29337237).
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  14. López-Espíndola, D.; Morales-Bastos, C.; Grijota-Martínez, C.; Liao, X.H.; Lev, D.; Sugo, E.; Verge, C.F.; Refetoff, S.; Bernal, J.; Guadaño-Ferraz, A. "Mutations of the thyroid hormone transporter MCT8 cause prenatal brain damage and persistent hypomyelination.". J. Clin. Endocrinol. Metab.. 99(12): E2799-804. (2014). (PMID: 25222753).
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  15. Grijota-Martínez, C.; Díez, D.; Morreale de Escobar, G.; Bernal, J.; Morte, B. "Lack of action of exogenously administered T3 on the fetal rat brain despite expression of the monocarboxylate transporter 8.". Endocrinology. 152(4): 1713-1721. (2011). (PMID: 21303950).
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  16. Grijota-Martínez, C.; Samarut, E.; Scanlan, T.S.; Morte, B.; Bernal, J. "In vivo activity of the thyroid hormone receptor beta- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain.". Endocrinology. 152(3): 1136-1142. (2011). (PMID: 21239431).
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  17. Morte, B.; Ceballos, A.; Diez, D.; Grijota-Martínez, C.; Dumitrescu, A.M.; Di Cosmo, C.; Galton, V.A.; Refetoff, S.; Bernal, J. "Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.". Endocrinology. 151(5): 2381-2387. (2010). (PMID: 20211971).
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  18. Morte, B.; Díez, D.; Ausó, E.; Belinchón, M.M.; Gil-Ibáñez, P.; Grijota-Martínez, C.; Navarro, D.; de Escobar, G.M.; Berbel, P.; Bernal, J. "Thyroid hormone regulation of gene expression in the developing rat fetal cerebral cortex: prominent role of the Ca2+/calmodulin-dependent protein kinase IV pathway.". Endocrinology. 151(2): 810-820. (2010). (PMID: 20056827).
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  19. Ceballos, A.; Belinchon, M.M.; Sanchez-Mendoza, E.; Grijota-Martinez, C.; Dumitrescu, A.M.; Refetoff, S.; Morte, B.; Bernal, J. "Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine.". Endocrinology. 150(5): 2491-2496. (2009). (PMID: 19147674).
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  20. Del Carmen Grijota-Martínez, M.; Ortega, C.; Bernal, J. "Direct action of triiodothyronine on gene expression in the neonatal brain and cerebellum.". Endocrinol Nutr. 55(8): 319-325. (2008). (PMID: 22975595).
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  21. Diez, D.; Grijota-Martinez, C.; Agretti, P.; De Marco, G.; Tonacchera, M.; Pinchera, A.; de Escobar, G.M.; Bernal, J.; Morte, B. "Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum.". Endocrinology. 149(8): 3989-4000. (2008). (PMID: 18467437).
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  22. Quignodon, L.; Grijota-Martinez, C.; Compe, E.; Guyot, R.; Allioli, N.; Laperrière, D.; Walker, R.; Meltzer, P.; Mader, S.; Samarut, J.; Flamant, F. "A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum.". J. Mol. Endocrinol.. 39(1): 17-28. (2007). (PMID: 17601882).
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Instituto de Investigaciones Biomédicas "Alberto Sols"
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