Palomo-Guerrero, M.; Cosgaya, J.M.; Gella, A.; Casals, N.; Grijota-Martinez, C. "Uridine-5'-Triphosphate Partially Blocks Differentiation Signals and Favors a more Repair State in Cultured rat Schwann Cells.". Neuroscience. 372(): 255-265. (2018). (PMID: 29337237).
Bernardo, A.R.; Cosgaya, J.M.; Aranda, A.; Jiménez-Lara, A.M. "Pro-apoptotic signaling induced by Retinoic acid and dsRNA is under the control of Interferon Regulatory Factor-3 in breast cancer cells.". Apoptosis. (): . (2017). (PMID: 28409399).
Latasa, M.J.; Jiménez-Lara, A.M.; Cosgaya, J.M. "Retinoic acid regulates Schwann cell migration via NEDD9 induction by transcriptional and post-translational mechanisms.". Biochim. Biophys. Acta. (): . (2016). (PMID: 27085739).
Bernardo, A.R.; Cosgaya, J.M.; Aranda, A.; Jiménez-Lara, A.M. "Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells.". Cell Death Dis. 4(): e479. (2013). (PMID: 23370279).
Latasa, M.J.; Cosgaya, J.M. "Regulation of retinoid receptors by retinoic acid and axonal contact in Schwann cells.". PLoS ONE. 6(2): e17023. (2011). (PMID: 21386894).
Ng, B.K.; Chen, L.; Mandemakers, W.; Cosgaya, J.M.; Chan, J.R. "Anterograde transport and secretion of brain-derived neurotrophic factor along sensory axons promote Schwann cell myelination.". J. Neurosci.. 27(28): 7597-7603. (2007). (PMID: 17626221).
Saxena, S.; Howe, C.L.; Cosgaya, J.M.; Steiner, P.; Hirling, H.; Chan, J.R.; Weis, J.; Krüttgen, A. "Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking.". Mol. Cell. Neurosci.. 28(3): 571-587. (2005). (PMID: 15737746).
Cañón, E.; Cosgaya, J.M.; Scsucova, S.; Aranda, A. "Rapid effects of retinoic acid on CREB and ERK phosphorylation in neuronal cells.". Mol. Biol. Cell. 15(12): 5583-5592. (2004). (PMID: 15371543).
Tolwani, R.J.; Cosgaya, J.M.; Varma, S.; Jacob, R.; Kuo, L.E.; Shooter, E.M. "BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system.". J. Neurosci. Res.. 77(5): 662-669. (2004). (PMID: 15352212).
Saxena, S.; Howe, C.L.; Cosgaya, J.M.; Hu, M.; Weis, J.; Krüttgen, A. "Differences in the surface binding and endocytosis of neurotrophins by p75NTR.". Mol. Cell. Neurosci.. 26(2): 292-307. (2004). (PMID: 15207854).
Wu, Y.J.; Krüttgen, A.; Möller, J.C.; Shine, D.; Chan, J.R.; Shooter, E.M.; Cosgaya, J.M. "Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 are sorted to dense-core vesicles and released via the regulated pathway in primary rat cortical neurons.". J. Neurosci. Res.. 75(6): 825-834. (2004). (PMID: 14994343).
Cosgaya, J.M.; Chan, J.R.; Shooter, E.M. "The neurotrophin receptor p75NTR as a positive modulator of myelination.". Science. 298(5596): 1245-1248. (2002). (PMID: 12424382).
Chan, J.R.; Cosgaya, J.M.; Wu, Y.J.; Shooter, E.M. "Neurotrophins are key mediators of the myelination program in the peripheral nervous system.". Proc. Natl. Acad. Sci. U.S.A.. 98(25): 14661-14668. (2001). (PMID: 11717413).
Cosgaya, J.M.; Shooter, E.M. "Binding of nerve growth factor to its p75 receptor in stressed cells induces selective IkappaB-beta degradation and NF-kappaB nuclear translocation.". J. Neurochem.. 79(2): 391-399. (2001). (PMID: 11677267).
Cosgaya, J.M.; Aranda, A. "Nerve growth factor activates the RARbeta2 promoter by a Ras-dependent mechanism.". J. Neurochem.. 76(3): 661-671. (2001). (PMID: 11158236).
Vesa, J.; Krüttgen, A.; Cosgaya, J.M.; Shooter, E.M. "Palmitoylation of the p75 neurotrophin receptor has no effect on its interaction with TrkA or on TrkA-mediated down-regulation of cell adhesion molecules.". J. Neurosci. Res.. 62(2): 225-233. (2000). (PMID: 11020215).
Cosgaya, J.M.; Aranda, A. "The ras oncogene inhibits growth factor inducibility of early response genes, and promotes selectively expression of NGFI-A in a PC12 cell line.". FEBS Lett.. 445(2-3): 329-332. (1999). (PMID: 10094483).
Cosgaya, J.M.; Aranda, A.; Cruces, J.; Martín-Blanco, E. "Neuronal differentiation of PC12 cells induced by engrailed homeodomain is DNA-binding specific and independent of MAP kinases.". J. Cell. Sci.. 111 ( Pt 16)(): 2377-2384. (1998). (PMID: 9683632).
Cosgaya, J.M.; Pérez-Juste, G.; Aranda, A. "Retinoic acid regulates selectively the expression of immediate early response genes in PC12 cells.". FEBS Lett.. 429(3): 254-258. (1998). (PMID: 9662427).
Cosgaya, J.M.; Perez-Juste, G.; Castillo, A.I.; Aranda, A. "Growth factor ligands of tyrosine kinase receptors activate the Rous sarcoma virus promoter by a Ras- and Raf-dependent mechanism.". Gene. 188(2): 291-293. (1997). (PMID: 9133605).
Cosgaya, J.M.; Recio, J.A.; Aranda, A. "Influence of Ras and retinoic acid on nerve growth factor induction of transin gene expression in PC12 cells.". Oncogene. 14(14): 1687-1696. (1997). (PMID: 9135070).
Cosgaya, J.M.; Perona, R.; Aranda, A. "Retinoic acid induces secretion of transforming growth factors by PC12 pheochromocytoma cells.". Oncogene. 14(5): 579-587. (1997). (PMID: 9053856).
Cosgaya, J.M.; Latasa, M.J.; Pascual, A. "Nerve growth factor and ras regulate beta-amyloid precursor protein gene expression in PC12 cells.". J. Neurochem.. 67(1): 98-9104. (1996). (PMID: 8667031).
Cosgaya, J.M.; Aranda, A. "Ras- and Raf-mediated regulation of transforming growth factor beta 1 gene expression by ligands of tyrosine kinase receptors in PC12 cells.". Oncogene. 12(12): 2651-2660. (1996). (PMID: 8700524).
Cosgaya, J.M.; Garcia-Villalba, P.; Perona, R.; Aranda, A. "Comparison of the effects of retinoic acid and nerve growth factor on PC12 cell proliferation, differentiation, and gene expression.". J. Neurochem.. 66(1): 89-98. (1996). (PMID: 8522994).
Cosgaya, J.M.; Aranda, A. "Nerve growth factor regulates transforming growth factor-beta 1 gene expression by both transcriptional and posttranscriptional mechanisms in PC12 cells.". J. Neurochem.. 65(6): 2484-2490. (1995). (PMID: 7595542).
Instituto de Investigaciones Biomédicas "Alberto Sols"
C/Arturo Duperier 4. 28029 Madrid. (Spain)
Tel +(34) 91 585 4400 // Fax +(34) 91 558 4401 Email:Info