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PUBLICACIONES

 

 

spacerTrabajos Publicados por Ignacio Palmero Rodríguez
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  1. Flores, N.G.; Fernández-Aroca, D.M.; Garnés-García, C.; Domínguez-Calvo, A.; Jiménez-Suárez, J.; Sabater, S.; Fernández-Aroca, P.; Andrés, I.; Cimas, F.J.; de Cárcer, G.; Belandia, B.; Palmero, I.; Huertas, P.; Ruiz-Hidalgo, M.J.; Sánchez-Prieto, R. "The CDK12-BRCA1 signaling axis mediates dinaciclib-associated radiosensitivity through p53-mediated cellular senescence.". Mol Oncol. (): . (2024). (PMID: 39626031).
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  2. de Lope, C.; García-Lucena, R.; Magariños, M.; León, Y.; Casa-Rodríguez, N.; Contreras, N.; Escudero-Iriarte, C.; Varela-Nieto, I.; Maire, P.; Palmero, I. "Dysfunction of programmed embryo senescence is linked to genetic developmental defects.". Development. (): . (2023). (PMID: 37017267).
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  3. López-Antona, I.; Contreras-Jurado, C.; Luque-Martín, L.; Carpintero-Leyva, A.; González-Méndez, P.; Palmero, I. "Dynamic regulation of myofibroblast phenotype in cellular senescence.". Aging Cell. (): e13580. (2022). (PMID: 35266275).
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  4. Palmero, I.; Gorgoulis, V.; Varela-Nieto, I. "Editorial: The Role of Cellular Senescence in Health and Disease.". Front Cell Neurosci. 16(): 882417. (2022). (PMID: 35431814).
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  5. Benítez, S.; Cordero, A.; Santamaría, P.G.; Redondo-Pedraza, J.; Rocha, A.S.; Collado-Solé, A.; Jimenez, M.; Sanz-Moreno, A.; Yoldi, G.; Santos, J.C.; De Benedictis, I.; Gómez-Aleza, C.; Da Silva-Álvarez, S.; Troulé, K.; Gómez-López, G.; Alcazar, N.; Palmero, I.; Collado, M.; Serrano, M.; Gonzalez-Suarez, E. "RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness.". Dev Cell. (): . (2021). (PMID: 34004159).
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  6. Ormaza, G.; Rodríguez, J.A.; Ibáñez de Opakua, A.; Merino, N.; Villate, M.; Gorroño, I.; Rábano, M.; Palmero, I.; Vilaseca, M.; Kypta, R.; Vivanco, M.D.M.; Rojas, A.L.; Blanco, F.J. "The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.". J. Mol. Biol.. 431(12): 2298-2319. (2019). (PMID: 31026448).
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  7. De Lope, C.; Martín-Alonso, S.; Auzmendi-Iriarte, J.; Escudero, C.; Mulet, I.; Larrasa-Alonso, J.; López-Antona, I.; Matheu, A.; Palmero, I. "SIX1 represses senescence and promotes SOX2-mediated cellular plasticity during tumorigenesis.". Sci Rep. 9(1): 1412. (2019). (PMID: 30723235).
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  8. Varela-Nieto, I.; Palmero, I.; Magariños, M. "Complementary and distinct roles of autophagy, apoptosis and senescence during early inner ear development.". Hear. Res.. (): . (2019). (PMID: 30711386).
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  9. Adrados, I.; Larrasa-Alonso, J.; Galarreta, A.; López-Antona, I.; Menéndez, C.; Abad, M.; Gil, J.; Moreno-Bueno, G.; Palmero, I. "The homeoprotein SIX1 controls cellular senescence through the regulation of p16INK4A and differentiation-related genes.". Oncogene. 35(27): 3485-3494. (2016). (PMID: 26500063).
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  10. Hernández-Sánchez, M.; Poch, E.; Guasch, R.M.; Ortega, J.; López-Almela, I.; Palmero, I.; Pérez-Roger, I. "RhoE is required for contact inhibition and negatively regulates tumor initiation and progression.". Oncotarget. 6(19): 17479-17490. (2015). (PMID: 26036260).
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  11. Menéndez, C.; Adrados, I.; Fernández-Barral, A.; Jiménez, B.; Flores, J.M.; Cañamero, M.; Fuchtbauer, E.M.; Beermann, F.; Palmero, I. "Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.". Pigment Cell Melanoma Res. 27(4): 674-677. (2014). (PMID: 24655373).
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  12. Fernández-Barral, A.; Orgaz, J.L.; Baquero, P.; Ali, Z.; Moreno, A.; Tiana, M.; Gómez, V.; Riveiro-Falkenbach, E.; Cañadas, C.; Zazo, S.; Bertolotto, C.; Davidson, I.; Rodríguez-Peralto, J.L.; Palmero, I.; Rojo, F.; Jensen, L.D.; del Peso, L.; Jiménez, B. "Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.". Neoplasia. 16(6): 529-542. (2014). (PMID: 25030625).
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  13. Moreno, A.; Soleto, I.; García-Sanz, P.; Moreno-Bueno, G.; Palmero, I. "ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth.". Oncogene. 33(15): 1945-1953. (2014). (PMID: 23604125).
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  14. Gómez-Cabello, D.; Adrados, I.; Gamarra, D.; Kobayashi, H.; Takatsu, Y.; Takatsu, K.; Gil, J.; Palmero, I. "DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts.". Aging Cell. 12(5): 923-931. (2013). (PMID: 23773483).
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  15. Gómez-Cabello, D.; Adrados, I.; Palmero, I. "microRNA biogenesis and senescence.". Aging (Albany NY). 5(10): 721-722. (2013). (PMID: 24142392).
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  16. Diaz-Rodriguez, E.; García-Lavandeira, M.; Perez-Romero, S.; Senra, A.; Cañibano, C.; Palmero, I.; Borrello, M.G.; Dieguez, C.; Alvarez, C.V. "Direct promoter induction of p19Arf by Pit-1 explains the dependence receptor RET/Pit-1/p53-induced apoptosis in the pituitary somatotroph cells.". Oncogene. 31(23): 2824-2835. (2012). (PMID: 22020338).
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  17. Culurgioni, S.; Muñoz, I.G.; Moreno, A.; Palacios, A.; Villate, M.; Palmero, I.; Montoya, G.; Blanco, F.J. "Crystal structure of inhibitor of growth 4 (ING4) dimerization domain reveals functional organization of ING family of chromatin-binding proteins.". J. Biol. Chem.. 287(14): 10876-10884. (2012). (PMID: 22334692).
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  18. Palmero, I. "New role for Spinophilin in tumor suppression.". Cell Cycle. 10(20): 3427. (2011). (PMID: 22024930).
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  19. Abad, M.; Moreno, A.; Palacios, A.; Narita, M.; Blanco, F.; Moreno-Bueno, G.; Narita, M.; Palmero, I. "The tumor suppressor ING1 contributes to epigenetic control of cellular senescence.". Aging Cell. 10(1): 158-171. (2011). (PMID: 21078114).
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  20. Moreno, A.; Palacios, A.; Orgaz, J.L.; Jimenez, B.; Blanco, F.J.; Palmero, I. "Functional impact of cancer-associated mutations in the tumor suppressor protein ING4.". Carcinogenesis. 31(11): 1932-1938. (2010). (PMID: 20705953).
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  21. Gómez-Cabello, D.; Callejas, S.; Benguría, A.; Moreno, A.; Alonso, J.; Palmero, I. "Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1.". Cancer Res.. 70(5): 1866-1874. (2010). (PMID: 20179197).
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  22. Palacios, A.; Moreno, A.; Oliveira, B.L.; Rivera, T.; Prieto, J.; García, P.; Fernández-Fernández, M.R.; Bernadó, P.; Palmero, I.; Blanco, F.J. "The dimeric structure and the bivalent recognition of H3K4me3 by the tumor suppressor ING4 suggests a mechanism for enhanced targeting of the HBO1 complex to chromatin.". J. Mol. Biol.. 396(4): 1117-1127. (2010). (PMID: 20053357).
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  23. Menéndez, C.; Abad, M.; Gómez-Cabello, D.; Moreno, A.; Palmero, I. "ING proteins in cellular senescence.". Curr Drug Targets. 10(5): 406-417. (2009). (PMID: 19442113).
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  24. Abad, M.; Menéndez, C.; Füchtbauer, A.; Serrano, M.; Füchtbauer, E.M.; Palmero, I. "Ing1 mediates p53 accumulation and chromatin modification in response to oncogenic stress.". J. Biol. Chem.. 282(42): 31060-31067. (2007). (PMID: 17693408).
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  25. González, L.; Freije, J.M.; Cal, S.; López-Otín, C.; Serrano, M.; Palmero, I. "A functional link between the tumour suppressors ARF and p33ING1.". Oncogene. 25(37): 5173-5179. (2006). (PMID: 16607280).
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  26. Goeman, F.; Thormeyer, D.; Abad, M.; Serrano, M.; Schmidt, O.; Palmero, I.; Baniahmad, A. "Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras.". Mol. Cell. Biol.. 25(1): 422-431. (2005). (PMID: 15601862).
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  27. Palmero, I.; Murga, M.; Zubiaga, A.; Serrano, M. "Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2.". Oncogene. 21(19): 2939-2947. (2002). (PMID: 12082524).
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  28. Pantoja, C.; Palmero, I.; Serrano, M. "Identification of the gene immediately downstream of the murine INK4a/ARF locus.". Exp. Gerontol.. 36(8): 1289-1302. (2001). (PMID: 11602205).
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  29. Palmero, I.; Pantoja, C.; Serrano, M. "p19ARF links the tumour suppressor p53 to Ras.". Nature. 395(6698): 125-126. (1998). (PMID: 9744268).
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  30. Stott, F.J.; Bates, S.; James, M.C.; McConnell, B.B.; Starborg, M.; Brookes, S.; Palmero, I.; Ryan, K.; Hara, E.; Vousden, K.H.; Peters, G. "The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.". EMBO J.. 17(17): 5001-5014. (1998). (PMID: 9724636).
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  31. Palmero, I.; McConnell, B.; Parry, D.; Brookes, S.; Hara, E.; Bates, S.; Jat, P.; Peters, G. "Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status.". Oncogene. 15(5): 495-503. (1997). (PMID: 9247303).
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  32. Sinclair, A.J.; Palmero, I.; Holder, A.; Peters, G.; Farrell, P.J. "Expression of cyclin D2 in Epstein-Barr virus-positive Burkitt's lymphoma cell lines is related to methylation status of the gene.". J. Virol.. 69(2): 1292-1295. (1995). (PMID: 7529333).
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  33. Macías, M.T.; Palmero, I.; Sastre, L. "Cloning of a cDNA encoding an Artemia franciscana Na/K ATPase alpha-subunit.". Gene. 105(2): 197-204. (1991). (PMID: 1657719).
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  34. Palmero, I.; Sastre, L. "Complementary DNA cloning of a protein highly homologous to mammalian sarcoplasmic reticulum Ca-ATPase from the crustacean Artemia.". J. Mol. Biol.. 210(4): 737-748. (1989). (PMID: 2533270).
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  35. Díaz-Guerra, M.; Quintanilla, M.; Palmero, I.; Sastre, L.; Renart, J. "Differential expression of a gene highly homologous to c-ras during the development of the brine shrimp Artemia.". Biochem. Biophys. Res. Commun.. 162(2): 802-808. (1989). (PMID: 2502981).
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  36. Palmero, I.; Renart, J.; Sastre, L. "Isolation of cDNA clones coding for mitochondrial 16S ribosomal RNA from the crustacean Artemia.". Gene. 68(2): 239-248. (1988). (PMID: 3220256).
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