Franco-Caspueñas, S.; García-Montoya, C.; Contreras, J. ; Lassaletta, L. ; Varela-Nieto, I. ; Jiménez-Lara, A.M. "Uncovering cellular senescence as a therapeutic target in NF2-related vestibular schwannoma." . Hear Res. 455(): 109165. (2024). (PMID: 39647233).
Domínguez-Ruiz, M.; Murillo-Cuesta, S. ; Contreras, J. ; Cantero, M.; Garrido, G.; Martín-Bernardo, B.; Gómez-Rosas, E.; Fernández, A.; Del Castillo, F.J.; Montoliu, L.; Varela-Nieto, I. ; Del Castillo, I. "A murine model for the del(GJB6-D13S1830) deletion recapitulating the phenotype of human DFNB1 hearing impairment: generation and functional and histopathological study." . BMC Genomics. 25(1): 359. (2024). (PMID: 38605287).
Murillo-Cuesta, S. ; Celaya, A.M. ; Cervantes, B. ; Bermúdez-Muñoz, J.M. ; Rodríguez-de la Rosa, L. ; Contreras, J. ; Sánchez-Pérez, I. ; Varela-Nieto, I. "Therapeutic efficiency of the APAF-1 antagonist LPT99 in a rat model of cisplatin-induced hearing loss." . Clin Transl Med. 11(4): e363. (2021). (PMID: 33931965).
Murillo-Cuesta, S. ; Vallecillo, N. ; Cediel, R. ; Celaya, A.M. ; Lassaletta, L. ; Varela-Nieto, I. ; Contreras, J. "A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection." . J Vis Exp. (121): . (2017). (PMID: 28362376).
Fuentes-Santamaría, V.; Alvarado, J.C.; Rodríguez-de la Rosa, L. ; Murillo-Cuesta, S. ; Contreras, J. ; Juiz, J.M.; Varela-Nieto, I. "Erratum to: IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei." . Brain Struct Funct. 221(2): 1205. (2016). (PMID: 25416135).
Fuentes-Santamaría, V.; Alvarado, J.C.; Rodríguez-de la Rosa, L. ; Murillo-Cuesta, S. ; Contreras, J. ; Juiz, J.M.; Varela-Nieto, I. "IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei." . Brain Struct Funct. 221(2): 709-734. (2016). (PMID: 25378055).
Rodríguez-de la Rosa, L. ; Sánchez-Calderón, H. ; Contreras, J. ; Murillo-Cuesta, S. ; Falagan, S.; Avendaño, C.; Dopazo, J.; Varela-Nieto, I. ; Milo, M. "Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays." . Hear. Res.. (): . (2015). (PMID: 26341476).
Sanz, L. ; Murillo-Cuesta, S. ; Cobo, P.; Cediel, R. ; Contreras, J. ; Rivera, T. ; Varela-Nieto, I. ; Avendaño, C. "Corrigendum to: Swept-sine noise-induced damage as a hearing loss model for preclinical assays." . Front Aging Neurosci. 7(): 79. (2015). (PMID: 26029100).
Murillo-Cuesta, S. ; Rodríguez-de la Rosa, L. ; Contreras, J. ; Celaya, A.M. ; Camarero, G. ; Rivera, T. ; Varela-Nieto, I. "Corrigendum: Transforming growth factor β1 inhibition protects from noise-induced hearing loss." . Front Aging Neurosci. 7(): 72. (2015). (PMID: 26005416).
López, I.P.; Rodriguez-de la Rosa, L. ; Pais, R.S.; Piñeiro-Hermida, S.; Torrens, R.; Contreras, J. ; Varela-Nieto, I. ; Pichel, J.G. "Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r (fl/fl) double transgenic mice." . Transgenic Res.. 24(2): 279-294. (2015). (PMID: 25238791).
Murillo-Cuesta, S. ; Rodríguez-de la Rosa, L. ; Contreras, J. ; Celaya, A.M. ; Camarero, G. ; Rivera, T. ; Varela-Nieto, I. "Transforming growth factor β1 inhibition protects from noise-induced hearing loss." . Front Aging Neurosci. 7(): 32. (2015). (PMID: 25852546).
Sanz, L. ; Murillo-Cuesta, S. ; Cobo, P.; Cediel-Algovia, R.; Contreras, J. ; Rivera, T. ; Varela-Nieto, I. ; Avendaño, C. "Swept-sine noise-induced damage as a hearing loss model for preclinical assays." . Front Aging Neurosci. 7(): 7. (2015). (PMID: 25762930).
Muñoz-Espín, D.; Cañamero, M.; Maraver, A.; Gómez-López, G.; Contreras, J. ; Murillo-Cuesta, S. ; Rodríguez-Baeza, A.; Varela-Nieto, I. ; Ruberte, J.; Collado, M.; Serrano, M. "Programmed cell senescence during mammalian embryonic development." . Cell. 155(5): 1104-1118. (2013). (PMID: 24238962).
Varela-Nieto, I. ; Murillo-Cuesta, S. ; Rodríguez-de la Rosa, L. ; Lassatetta, L.; Contreras, J. "IGF-I deficiency and hearing loss: molecular clues and clinical implications." . Pediatr Endocrinol Rev. 10(4): 460-472. (2013). (PMID: 23957197).
Magariños, M. ; Contreras, J. ; Aburto, M.R. ; Varela-Nieto, I. "Early development of the vertebrate inner ear." . Anat Rec (Hoboken). 295(11): 1775-1790. (2012). (PMID: 23044927).
Riquelme, R. ; Cediel, R. ; Contreras, J. ; la Rosa Lourdes, R.D. ; Murillo-Cuesta, S. ; Hernandez-Sanchez, C.; Zubeldia, J.M. ; Cerdan, S. ; Varela-Nieto, I. "A comparative study of age-related hearing loss in wild type and insulin-like growth factor I deficient mice." . Front Neuroanat. 4(): 27. (2010). (PMID: 20661454).
Murillo-Cuesta, S. ; Contreras, J. ; Cediel, R. ; Varela-Nieto, I. "Comparison of different aminoglycoside antibiotic treatments to refine ototoxicity studies in adult mice." . Lab. Anim.. 44(2): 124-131. (2010). (PMID: 19858169).
Murillo-Cuesta, S. ; Contreras, J. ; Zurita, E.; Cediel, R. ; Cantero, M.; Varela-Nieto, I. ; Montoliu, L. "Melanin precursors prevent premature age-related and noise-induced hearing loss in albino mice." . Pigment Cell Melanoma Res. 23(1): 72-83. (2010). (PMID: 19843244).
Rodríguez-de la Rosa, L. ; Contreras-Rodríguez, J. ; Cediel-Algovia, R. ; León, Y. ; Sánchez-Calderón, H. ; Murillo-Cuesta, S. ; Riquelme-Galiana, R. ; de Diego-Sastre, J.I. ; Prim-Espada, M.P. ; Varela-Nieto, I. ; , . "[Neurotrophic action of insulin-like growth factor-I in the inner ear]." . Rev Neurol. 45(4): 245-250. (2008). (PMID: 17668408).
Cediel, R. ; Riquelme, R. ; Contreras, J. ; Díaz, A.; Varela-Nieto, I. "Sensorineural hearing loss in insulin-like growth factor I-null mice: a new model of human deafness." . Eur J Neurosci. 23(2): 587-590. (2006). (PMID: 16420467).
Varela-Nieto, I. ; Morales-Garcia, J.A. ; Vigil, P.; Diaz-Casares, A.; Gorospe, I. ; Sánchez-Galiano, S.; Cañon, S. ; Camarero, G. ; Contreras, J. ; Cediel, R. ; Leon, Y. "Trophic effects of insulin-like growth factor-I (IGF-I) in the inner ear." . Hear. Res.. 196(1-2): 19-25. (2004). (PMID: 15464297).
Camarero, G. ; Villar, M.A.; Contreras, J. ; Fernández-Moreno, C.; Pichel, J.G.; Avendaño, C.; Varela-Nieto, I. "Cochlear abnormalities in insulin-like growth factor-1 mouse mutants." . Hear. Res.. 170(1-2): 2-11. (2002). (PMID: 12208536).
Camarero, G. ; Avendano, C.; Fernandez-Moreno, C.; Villar, A.; Contreras, J. ; de Pablo, F.; Pichel, J.G.; Varela-Nieto, I. "Delayed inner ear maturation and neuronal loss in postnatal Igf-1-deficient mice." . J. Neurosci.. 21(19): 7630-7641. (2001). (PMID: 11567053).