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PUBLICACIONES

 

 

spacerTrabajos Publicados por María Belén Peral Fuentes
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  1. Bonzon-Kulichenko, E.; Camafeita, E.; López, J.A.; Gómez-Serrano, M.; Jorge, I.; Calvo, E.; Núñez, E.; Trevisan-Herraz, M.; Bagwan, N.; Bárcena, J.A.; Peral, B.; Vázquez, J. "Improved integrative analysis of the thiol redox proteome using filter-aided sample preparation.". J Proteomics. 214(): 103624. (2019). (PMID: 31874222).
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  2. Ortega, F.J.; Moreno-Navarrete, J.M.; Mercader, J.M.; Gómez-Serrano, M.; García-Santos, E.; Latorre, J.; Lluch, A.; Sabater, M.; Caballano-Infantes, E.; Guzmán, R.; Macías-González, M.; Buxo, M.; Gironés, J.; Vilallonga, R.; Naon, D.; Botas, P.; Delgado, E.; Corella, D.; Burcelin, R.; Frühbeck, G.; Ricart, W.; Simó, R.; Castrillon-Rodríguez, I.; Tinahones, F.J.; Bosch, F.; Vidal-Puig, A.; Malagón, M.M.; Peral, B.; Zorzano, A.; Fernández-Real, J.M. "Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function.". FASEB J.. 33(8): 9656-9671. (2019). (PMID: 31145872).
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  3. Gómez-Serrano, M.; Camafeita, E.; Loureiro, M.; Peral, B. "Mitoproteomics: Tackling Mitochondrial Dysfunction in Human Disease.". Oxid Med Cell Longev. 2018(): 1435934. (2018). (PMID: 30533169).
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  4. Gómez-Serrano, M.; Camafeita, E.; López, J.A.; Rubio, M.A.; Bretón, I.; García-Consuegra, I.; García-Santos, E.; Lago, J.; Sánchez-Pernaute, A.; Torres, A.; Vázquez, J.; Peral, B. "Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes.". Redox Biol. 11(): 415-428. (2016). (PMID: 28064117).
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  5. Soto, D.; Gomez-Serrano, M.; Pieralisi, A.; Calvo, J.C.; Peral, B.; Guerra, L.N. "N-acetylcysteine inhibits kinase phosphorylation during 3T3-L1 adipocyte differentiation.". Redox Rep.. (): 1-7. (2016). (PMID: 27670786).
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  6. Gómez-Serrano, M.; Camafeita, E.; García-Santos, E.; López, J.A.; Rubio, M.A.; Sánchez-Pernaute, A.; Torres, A.; Vázquez, J.; Peral, B. "Proteome-wide alterations on adipose tissue from obese patients as age-, diabetes- and gender-specific hallmarks.". Sci Rep. 6(): 25756. (2016). (PMID: 27160966).
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  7. Roca-Rodríguez, M.M.; El Bekay, R.; Garrido-Sanchez, L.; Gómez-Serrano, M.; Coin-Aragüez, L.; Oliva-Olivera, W.; Lhamyani, S.; Clemente-Postigo, M.; García-Santos, E.; de Luna Diaz, R.; Yubero-Serrano, E.M.; Real, J.M.; Peral, B.; Tinahones, F.J. "Parathyroid Hormone-Related Protein, Human Adipose-Derived Stem Cells Adipogenic Capacity and Healthy Obesity.". J. Clin. Endocrinol. Metab.. 100(6): E826-35. (2015). (PMID: 25885945).
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  8. Malandrino, M.I.; Fucho, R.; Weber, M.; Calderon-Dominguez, M.; Mir, J.F.; Valcarcel, L.; Escoté, X.; Gomez-Serrano, M.; Peral, B.; Salvadó, L.; Fernandez-Veledo, S.; Casals, N.; Vazquez-Carrera, M.; Villarroya, F.; Vendrell, J.J.; Serra, D.; Herrero, L. "Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.". Am. J. Physiol. Endocrinol. Metab.. (): ajpendo.00362.2014. (2015). (PMID: 25714670).
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  9. Ortega, F.J.; Serrano, M.; Rodriguez-Cuenca, S.; Moreno-Navarrete, J.M.; Gómez-Serrano, M.; Sabater, M.; Rodriguez-Hermosa, J.I.; Xifra, G.; Ricart, W.; Peral, B.; Vidal-Puig, A.; Fernández-Real, J.M. "Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression.". J. Mol. Med.. 93(1): 83-92. (2015). (PMID: 25249007).
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  10. Guerra, L.N.; Suarez, C.; Soto, D.; Schiappacasse, A.; Sapochnik, D.; Sacca, P.; Piwien-Pilipuk, G.; Peral, B.; Calvo, J.C. "GAL3ST2 from mammary gland epithelial cells affects differentiation of 3T3-L1 preadipocytes.". Clin Transl Oncol. (): . (2014). (PMID: 25532485).
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  11. Marino, A.; Menghini, R.; Fabrizi, M.; Casagrande, V.; Mavilio, M.; Stoehr, R.; Candi, E.; Mauriello, A.; Moreno-Navarrete, J.M.; Gómez-Serrano, M.; Peral, B.; Melino, G.; Lauro, R.; Fernandez Real, J.M.; Federici, M. "ITCH deficiency protects from diet-induced obesity.". Diabetes. 63(2): 550-561. (2014). (PMID: 24170694).
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  12. Calzadilla, P.; Gómez-Serrano, M.; García-Santos, E.; Schiappacasse, A.; Abalde, Y.; Calvo, J.C.; Peral, B.; Guerra, L.N. "N-Acetylcysteine affects obesity-related protein expression in 3T3-L1 adipocytes.". Redox Rep.. 18(6): 210-218. (2013). (PMID: 24112955).
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  13. Moreno-Navarrete, J.M.; Ortega, F.; Gómez-Serrano, M.; García-Santos, E.; Ricart, W.; Tinahones, F.; Mingrone, G.; Peral, B.; Fernández-Real, J.M. "The MRC1/CD68 ratio is positively associated with adipose tissue lipogenesis and with muscle mitochondrial gene expression in humans.". PLoS ONE. 8(8): e70810. (2013). (PMID: 23951013).
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  14. Queipo-Ortuño, M.I.; Escoté, X.; Ceperuelo-Mallafré, V.; Garrido-Sanchez, L.; Miranda, M.; Clemente-Postigo, M.; Pérez-Pérez, R.; Peral, B.; Cardona, F.; Fernández-Real, J.M.; Tinahones, F.J.; Vendrell, J. "FABP4 dynamics in obesity: discrepancies in adipose tissue and liver expression regarding circulating plasma levels.". PLoS One. 7(11): e48605. (2012). (PMID: 23139800).
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  15. Ortega, F.J.; Moreno-Navarrete, J.M.; Mayas, D.; García-Santos, E.; Gómez-Serrano, M.; Rodriguez-Hermosa, J.I.; Ruiz, B.; Ricart, W.; Tinahones, F.J.; Frühbeck, G.; Peral, B.; Fernández-Real, J.M. "Breast cancer 1 (BrCa1) may be behind decreased lipogenesis in adipose tissue from obese subjects.". PLoS ONE. 7(5): e33233. (2012). (PMID: 22666314).
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  16. Pérez-Pérez, R.; García-Santos, E.; Ortega-Delgado, F.J.; López, J.A.; Camafeita, E.; Ricart, W.; Fernández-Real, J.M.; Peral, B. "Attenuated metabolism is a hallmark of obesity as revealed by comparative proteomic analysis of human omental adipose tissue.". J Proteomics. 75(3): 783-795. (2012). (PMID: 21989264).
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  17. Pérez-Pérez, R.; López, J.A.; García-Santos, E.; Camafeita, E.; Gómez-Serrano, M.; Ortega-Delgado, F.J.; Ricart, W.; Fernández-Real, J.M.; Peral, B. "Uncovering suitable reference proteins for expression studies in human adipose tissue with relevance to obesity.". PLoS ONE. 7(1): e30326. (2012). (PMID: 22272336).
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  18. Moreno-Navarrete, J.M.; Ortega, F.; Serrano, M.; Pérez-Pérez, R.; Sabater, M.; Ricart, W.; Tinahones, F.; Peral, B.; Fernández-Real, J.M. "Decreased STAMP2 expression in association with visceral adipose tissue dysfunction.". J. Clin. Endocrinol. Metab.. 96(11): E1816-25. (2011). (PMID: 21849520).
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  19. Vendrell, J.; El Bekay, R.; Peral, B.; García-Fuentes, E.; Megia, A.; Macias-Gonzalez, M.; Fernández Real, J.; Jimenez-Gomez, Y.; Escoté, X.; Pachón, G.; Simó, R.; Selva, D.M.; Malagón, M.M.; Tinahones, F.J. "Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistance.". Endocrinology. 152(11): 4072-4079. (2011). (PMID: 21862620).
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  20. Kilpeläinen, T.O.; Zillikens, M.C.; Stančákova, A.; Finucane, F.M.; Ried, J.S.; Langenberg, C.; Zhang, W.; Beckmann, J.S.; Luan, J.; Vandenput, L.; Styrkarsdottir, U.; Zhou, Y.; Smith, A.V.; Zhao, J.H.; Amin, N.; Vedantam, S.; Shin, S.Y.; Haritunians, T.; Fu, M.; Feitosa, M.F.; Kumari, M.; Halldorsson, B.V.; Tikkanen, E.; Mangino, M.; Hayward, C.; Song, C.; Arnold, A.M.; Aulchenko, Y.S.; Oostra, B.A.; Campbell, H.; Cupples, L.A.; Davis, K.E.; Döring, A.; Eiriksdottir, G.; Estrada, K.; Fernández-Real, J.M.; Garcia, M.; Gieger, C.; Glazer, N.L.; Guiducci, C.; Hofman, A.; Humphries, S.E.; Isomaa, B.; Jacobs, L.C.; Jula, A.; Karasik, D.; Karlsson, M.K.; Khaw, K.T.; Kim, L.J.; Kivimäki, M.; Klopp, N.; Kühnel, B.; Kuusisto, J.; Liu, Y.; Ljunggren, O.; Lorentzon, M.; Luben, R.N.; McKnight, B.; Mellström, D.; Mitchell, B.D.; Mooser, V.; Moreno, J.M.; Männistö, S.; O'Connell, J.R.; Pascoe, L.; Peltonen, L.; Peral, B.; Perola, M.; Psaty, B.M.; Salomaa, V.; Savage, D.B.; Semple, R.K.; Skaric-Juric, T.; Sigurdsson, G.; Song, K.S.; Spector, T.D.; Syvänen, A.C.; Talmud, P.J.; Thorleifsson, G.; Thorsteinsdottir, U.; Uitterlinden, A.G.; van Duijn, C.M.; Vidal-Puig, A.; Wild, S.H.; Wright, A.F.; Clegg, D.J.; Schadt, E.; Wilson, J.F.; Rudan, I.; Ripatti, S.; Borecki, I.B.; Shuldiner, A.R.; Ingelsson, E.; Jansson, J.O.; Kaplan, R.C.; Gudnason, V.; Harris, T.B.; Groop, L.; Kiel, D.P.; Rivadeneira, F.; Walker, M.; Barroso, I.; Vollenweider, P.; Waeber, G.; Chambers, J.C.; Kooner, J.S.; Soranzo, N.; Hirschhorn, J.N.; Stefansson, K.; Wichmann, H.E.; Ohlsson, C.; O'Rahilly, S.; Wareham, N.J.; Speliotes, E.K.; Fox, C.S.; Laakso, M.; Loos, R.J. "Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.". Nat. Genet.. 43(8): 753-760. (2011). (PMID: 21706003).
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  21. Ortega, F.J.; Vazquez-Martin, A.; Moreno-Navarrete, J.M.; Bassols, J.; Rodriguez-Hermosa, J.; Gironés, J.; Ricart, W.; Peral, B.; Tinahones, F.J.; Fruhbeck, G.; Menendez, J.A.; Fernández-Real, J.M. "Thyroid hormone responsive Spot 14 increases during differentiation of human adipocytes and its expression is down-regulated in obese subjects.". Int J Obes (Lond). 34(3): 487-499. (2010). (PMID: 20029374).
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  22. Ortega, F.J.; Moreno-Navarrete, J.M.; Pardo, G.; Sabater, M.; Hummel, M.; Ferrer, A.; Rodriguez-Hermosa, J.I.; Ruiz, B.; Ricart, W.; Peral, B.; Fernández-Real, J.M. "MiRNA expression profile of human subcutaneous adipose and during adipocyte differentiation.". PLoS ONE. 5(2): e9022. (2010). (PMID: 20126310).
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  23. Ortega, F.J.; Mayas, D.; Moreno-Navarrete, J.M.; Catalán, V.; Gómez-Ambrosi, J.; Esteve, E.; Rodriguez-Hermosa, J.I.; Ruiz, B.; Ricart, W.; Peral, B.; Fruhbeck, G.; Tinahones, F.J.; Fernández-Real, J.M. "The gene expression of the main lipogenic enzymes is downregulated in visceral adipose tissue of obese subjects.". Obesity (Silver Spring). 18(1): 13-20. (2010). (PMID: 19543203).
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  24. Ortega, F.J.; Moreno-Navarrete, J.M.; Ribas, V.; Esteve, E.; Rodriguez-Hermosa, J.I.; Ruiz, B.; Peral, B.; Ricart, W.; Zorzano, A.; Fernández-Real, J.M. "Subcutaneous fat shows higher thyroid hormone receptor-alpha1 gene expression than omental fat.". Obesity (Silver Spring). 17(12): 2134-2141. (2009). (PMID: 19360007).
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  25. Bassols, J.; Ortega, F.J.; Moreno-Navarrete, J.M.; Peral, B.; Ricart, W.; Fernández-Real, J.M. "Study of the proinflammatory role of human differentiated omental adipocytes.". J. Cell. Biochem.. 107(6): 1107-1117. (2009). (PMID: 19492335).
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  26. Peral, B.; Camafeita, E.; Fernández-Real, J.M.; López, J.A. "Tackling the human adipose tissue proteome to gain insight into obesity and related pathologies.". Expert Rev Proteomics. 6(4): 353-361. (2009). (PMID: 19681671).
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  27. Pérez-Pérez, R.; Ortega-Delgado, F.J.; García-Santos, E.; López, J.A.; Camafeita, E.; Ricart, W.; Fernández-Real, J.M.; Peral, B. "Differential proteomics of omental and subcutaneous adipose tissue reflects their unalike biochemical and metabolic properties.". J. Proteome Res.. 8(4): 1682-1693. (2009). (PMID: 19714809).
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  28. Cortón, M.; Botella-Carretero, J.I.; López, J.A.; Camafeita, E.; San Millán, J.L.; Escobar-Morreale, H.F.; Peral, B. "Proteomic analysis of human omental adipose tissue in the polycystic ovary syndrome using two-dimensional difference gel electrophoresis and mass spectrometry.". Hum. Reprod.. 23(3): 651-661. (2008). (PMID: 18156650).
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  29. Escobar-Morreale, H.F.; Insenser, M.; Cortón, M.; San Millán, J.L.; Peral, B. "Proteomics and genomics: A hypothesis-free approach to the study of the role of visceral adiposity in the pathogenesis of the polycystic ovary syndrome.". Proteomics Clin Appl. 2(3): 444-455. (2008). (PMID: 21136846).
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  30. Cortón, M.; Botella-Carretero, J.I.; Benguría, A.; Villuendas, G.; Zaballos, A.; San Millán, J.L.; Escobar-Morreale, H.F.; Peral, B. "Differential gene expression profile in omental adipose tissue in women with polycystic ovary syndrome.". J. Clin. Endocrinol. Metab.. 92(1): 328-337. (2007). (PMID: 17062763).
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  31. San Millán, J.L.; Cortón, M.; Villuendas, G.; Sancho, J.; Peral, B.; Escobar-Morreale, H.F. "Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity.". J. Clin. Endocrinol. Metab.. 89(6): 2640-2646. (2004). (PMID: 15181035).
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  32. Cortón, M.; Villuendas, G.; Botella, J.I.; San Millán, J.L.; Escobar-Morreale, H.F.; Peral, B. "Improved resolution of the human adipose tissue proteome at alkaline and wide range pH by the addition of hydroxyethyl disulfide.". Proteomics. 4(2): 438-441. (2004). (PMID: 14760714).
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  33. Peral, B.; San Millán, J.L.; Castello, R.; Moghetti, P.; Escobar-Morreale, H.F. "Comment: the methionine 196 arginine polymorphism in exon 6 of the TNF receptor 2 gene (TNFRSF1B) is associated with the polycystic ovary syndrome and hyperandrogenism.". J. Clin. Endocrinol. Metab.. 87(8): 3977-3983. (2002). (PMID: 12161545).
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  34. Escobar-Morreale, H.F.; Peral, B.; Villuendas, G.; Calvo, R.M.; Sancho, J.; San Millán, J.L. "Common single nucleotide polymorphisms in intron 3 of the calpain-10 gene influence hirsutism.". Fertil. Steril.. 77(3): 581-587. (2002). (PMID: 11872216).
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  35. Gratacòs, M.; Nadal, M.; Martín-Santos, R.; Pujana, M.A.; Gago, J.; Peral, B.; Armengol, L.; Ponsa, I.; Miró, R.; Bulbena, A.; Estivill, X. "A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders.". Cell. 106(3): 367-379. (2001). (PMID: 11509185).
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  36. Pujana, M.A.; Nadal, M.; Gratacòs, M.; Peral, B.; Csiszar, K.; González-Sarmiento, R.; Sumoy, L.; Estivill, X. "Additional complexity on human chromosome 15q: identification of a set of newly recognized duplicons (LCR15) on 15q11-q13, 15q24, and 15q26.". Genome Res.. 11(1): 98-9111. (2001). (PMID: 11156619).
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  37. Rossetti, S.; Strmecki, L.; Gamble, V.; Burton, S.; Sneddon, V.; Peral, B.; Roy, S.; Bakkaloglu, A.; Komel, R.; Winearls, C.G.; Harris, P.C. "Mutation analysis of the entire PKD1 gene: genetic and diagnostic implications.". Am. J. Hum. Genet.. 68(1): 46-63. (2001). (PMID: 11115377).
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  38. Sumoy, L.; Carim, L.; Escarceller, M.; Nadal, M.; Gratacòs, M.; Pujana, M.A.; Estivill, X.; Peral, B. "HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression.". Cytogenet. Cell Genet.. 88(1-2): 62-67. (2000). (PMID: 10773667).
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  39. Palou, E.; Pirotto, F.; Solé, J.; Freed, J.H.; Peral, B.; Vilardell, C.; Vilella, R.; Vives, J.; Gayá, A. "Genomic characterization of CD84 reveals the existence of five isoforms differing in their cytoplasmic domains.". Tissue Antigens. 55(2): 118-127. (2000). (PMID: 10746783).
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Instituto de Investigaciones Biomédicas "Alberto Sols"
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