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PUBLICACIONES

 

 

spacerTrabajos Publicados por Óscar Hernán Martínez-Costa Pérez
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  1. Samhan-Arias, A.K.; Poejo, J.; Marques-da-Silva, D.; Martínez-Costa, O.H.; Gutierrez-Merino, C. "Are There Lipid Membrane-Domain Subtypes in Neurons with Different Roles in Calcium Signaling?". Molecules. 28(23): . (2023). (PMID: 38067638).
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  2. Martínez-Costa, O.H.; Rodrigues-Miranda, L.; Clemente, S.M.; Parola, A.J.; Basilio, N.; Samhan-Arias, A.K. "The Use of Flavylium Salts as Dynamic Inhibitor Moieties for Human Cb5R.". Molecules. 28(1): . (2022). (PMID: 36615312).
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  3. Puente-Santamaria, L.; Sanchez-Gonzalez, L.; Pescador, N.; Martinez-Costa, O.; Ramos-Ruiz, R.; Del Peso, L. "Formal Meta-Analysis of Hypoxic Gene Expression Profiles Reveals a Universal Gene Signature.". Biomedicines. 10(9): . (2022). (PMID: 36140330).
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  4. Gutiérrez-Merino, C.; Martínez-Costa, O.H.; Monsalve, M.; Samhan-Arias, A.K. "Structural Features of Cytochrome b5-Cytochrome b5 Reductase Complex Formation and Implications for the Intramolecular Dynamics of Cytochrome b5 Reductase.". Int J Mol Sci. 23(1): . (2021). (PMID: 35008543).
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  5. Clemente, S.M.; Martínez-Costa, O.H.; Monsalve, M.; Samhan-Arias, A.K. "Targeting Lipid Peroxidation for Cancer Treatment.". Molecules. 25(21): . (2020). (PMID: 33167334).
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  6. Mayoral-Varo, V.; Calcabrini, A.; Sánchez-Bailón, M.P.; Martínez-Costa, Ó.H.; González-Páramos, C.; Ciordia, S.; Hardisson, D.; Aragón, J.J.; Fernández-Moreno, M.Á.; Martín-Pérez, J. "c-Src functionality controls self-renewal and glucose metabolism in MCF7 breast cancer stem cells.". PLoS ONE. 15(7): e0235850. (2020). (PMID: 32673341).
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  7. Mesquita, A.; Tábara, L.C.; Martinez-Costa, O.; Santos-Rodrigo, N.; Vincent, O.; Escalante, R. "Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase.". Open Biol. 5(8): . (2015). (PMID: 26246495).
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  8. Hermida, C.; Martínez-Costa, O.H.; Corrales, G.; Teruel, C.; Sánchez, V.; Sánchez, J.J.; Sarrión, D.; Ariza, M.J.; Codoceo, R.; Calvo, I.; Fernández-Mayoralas, A.; Aragón, J.J. "Improvement and validation of d-xylose determination in urine and serum as a new tool for the noninvasive evaluation of lactase activity in humans.". J. Clin. Lab. Anal.. 28(6): 478-486. (2014). (PMID: 24659338).
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  9. Aragón, J.J.; Hermida, C.; Martínez-Costa, O.H.; Sánchez, V.; Martín, I.; Sánchez, J.J.; Codoceo, R.; Cano, J.M.; Cano, A.; Crespo, L.; Torres, Y.; García, F.J.; Fernández-Mayoralas, A.; Solera, J.; Martínez, P. "Noninvasive diagnosis of hypolactasia with 4-Galactosylxylose (Gaxilose): a multicentre, open-label, phase IIB-III nonrandomized trial.". J. Clin. Gastroenterol.. 48(1): 29-36. (2014). (PMID: 23722657).
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  10. Hermida, C.; Guerra, P.; Martínez-Costa, O.H.; Sánchez, V.; Sánchez, J.J.; Solera, J.; Fernández-Mayoralas, A.; Codoceo, R.; Frías, J.; Aragón, J.J. "Phase I and phase IB clinical trials for the noninvasive evaluation of intestinal lactase with 4-galactosylxylose (gaxilose).". J. Clin. Gastroenterol.. 47(6): 501-508. (2013). (PMID: 23328304).
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  11. Martínez-Costa, O.H.; Sánchez, V.; Lázaro, A.; Hernández, E.D.; Tornheim, K.; Aragón, J.J. "Distinct functional roles of the two terminal halves of eukaryotic phosphofructokinase.". Biochem. J.. 445(2): 213-218. (2012). (PMID: 22530721).
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  12. Arechaga, I.; Martínez-Costa, O.H.; Ferreras, C.; Carrascosa, J.L.; Aragón, J.J. "Electron microscopy analysis of mammalian phosphofructokinase reveals an unusual 3-dimensional structure with significant implications for enzyme function.". FASEB J.. 24(12): 4960-4968. (2010). (PMID: 20732951).
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  13. Ferreras, C.; Hernández, E.D.; Martínez-Costa, O.H.; Aragón, J.J. "Subunit interactions and composition of the fructose 6-phosphate catalytic site and the fructose 2,6-bisphosphate allosteric site of mammalian phosphofructokinase.". J. Biol. Chem.. 284(14): 9124-9131. (2009). (PMID: 19218242).
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  14. Hermida, C.; Garcés, C.; de Oya, M.; Cano, B.; Martínez-Costa, O.H.; Rivero, S.; García-Ramírez, J.J.; Laborda, J.; Aragón, J.J. "The serum levels of the EGF-like homeotic protein dlk1 correlate with different metabolic parameters in two hormonally different children populations in Spain.". Clin. Endocrinol. (Oxf). 69(2): 216-224. (2008). (PMID: 18248640).
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  15. Martínez-Costa, O.H.; Sánchez-Martínez, C.; Sánchez, V.; Aragón, J.J. "Chimeric phosphofructokinases involving exchange of the N- and C-terminal halves of mammalian isozymes: implications for ligand binding sites.". FEBS Lett.. 581(16): 3033-3038. (2007). (PMID: 17544406).
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  16. Hermida, C.; Corrales, G.; Martínez-Costa, O.H.; Fernández-Mayoralas, A.; Aragón, J.J. "Noninvasive evaluation of intestinal lactase with 4-galactosylxylose: comparison with 3- and 2-galactosylxylose and optimization of the method in rats.". Clin Chem. 52(2): 270-277. (2006). (PMID: 16384892).
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  17. Flores, C.L.; Martínez-Costa, O.H.; Sánchez, V.; Gancedo, C.; Aragón, J.J. "The dimorphic yeast Yarrowia lipolytica possesses an atypical phosphofructokinase: characterization of the enzyme and its encoding gene.". Microbiology (Reading). 151(Pt 5): 1465-1474. (2005). (PMID: 15870456).
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  18. Marina, P.; Martínez-Costa, O.H.; Calderón, I.L.; Aragón, J.J. "Characterization of the aspartate kinase from Saccharomyces cerevisiae and of its interaction with threonine.". Biochem. Biophys. Res. Commun.. 321(3): 584-591. (2004). (PMID: 15358146).
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  19. Martínez-Costa, O.H.; Hermida, C.; Sánchez-Martínez, C.; Santamaría, B.; Aragón, J.J. "Identification of C-terminal motifs responsible for transmission of inhibition by ATP of mammalian phosphofructokinase, and their contribution to other allosteric effects.". Biochem. J.. 377(Pt 1): 77-84. (2004). (PMID: 12974670).
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  20. Santamaria, B.; Estevez, A.M.; Martinez-Costa, O.H.; Aragon, J.J. "Creation of an allosteric phosphofructokinase starting with a nonallosteric enzyme. The case of dictyostelium discoideum phosphofructokinase.". J. Biol. Chem.. 277(2): 1210-1216. (2002). (PMID: 11700322).
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Instituto de Investigaciones Biomédicas "Alberto Sols"
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