Martin-Puig, S.; Menendez-Montes, I. "Cardiac Metabolism.". Adv Exp Med Biol. 1441(): 365-396. (2024). (PMID: 38884721).
Menendez-Montes, I.; Villalba-Orero, M.; Escobar, B.; Martin-Puig, S. "Embryonic echocardiography for assessment of congenital and functional cardiac defects.". STAR Protoc. 2(4): 100980. (2021). (PMID: 34927090).
Izquierdo-Garcia, J.L.; Arias, T.; Rojas, Y.; Garcia-Ruiz, V.; Santos, A.; Martin-Puig, S.; Ruiz-Cabello, J. "Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension.". Front Cardiovasc Med. 5(): 110. (2018). (PMID: 30159317).
Izquierdo, H.M.; Brandi, P.; Gómez, M.J.; Conde-Garrosa, R.; Priego, E.; Enamorado, M.; Martínez-Cano, S.; Sánchez, I.; Conejero, L.; Jimenez-Carretero, D.; Martín-Puig, S.; Guilliams, M.; Sancho, D. "Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function.". Cell Rep. 24(7): 1738-1746. (2018). (PMID: 30110631).
Mira, E.; Carmona-Rodríguez, L.; Pérez-Villamil, B.; Casas, J.; Fernández-Aceñero, M.J.; Martínez-Rey, D.; Martín-González, P.; Heras-Murillo, I.; Paz-Cabezas, M.; Tardáguila, M.; Oury, T.D.; Martín-Puig, S.; Lacalle, R.A.; Fabriás, G.; Díaz-Rubio, E.; Mañes, S. "SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.". Nat Commun. 9(1): 575. (2018). (PMID: 29422508).
Menendez-Montes, I.; Escobar, B.; Palacios, B.; Gómez, M.J.; Izquierdo-Garcia, J.L.; Flores, L.; Jiménez-Borreguero, L.J.; Aragones, J.; Ruiz-Cabello, J.; Torres, M.; Martin-Puig, S. "Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.". Dev Cell. 39(6): 724-739. (2016). (PMID: 27997827).
Martin-Puig, S.; Tello, D.; Aragonés, J. "Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC.". Front Physiol. 6(): 137. (2015). (PMID: 26042040).
Martin-Puig, S.; Fuster, V.; Torres, M. "Heart repair: from natural mechanisms of cardiomyocyte production to the design of new cardiac therapies.". Ann N Y Acad Sci. 1254(): 71-81. (2012). (PMID: 22548572).
Acosta-Iborra, B.; Elorza, A.; Olazabal, I.M.; Martín-Cofreces, N.B.; Martin-Puig, S.; Miró, M.; Calzada, M.J.; Aragonés, J.; Sánchez-Madrid, F.; Landázuri, M.O. "Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor.". J Immunol. 182(5): 3155-3164. (2009). (PMID: 19234213).
Martin-Puig, S.; Wang, Z.; Chien, K.R. "Lives of a heart cell: tracing the origins of cardiac progenitors.". Cell Stem Cell. 2(4): 320-331. (2008). (PMID: 18397752).
Qyang, Y.; Martin-Puig, S.; Chiravuri, M.; Chen, S.; Xu, H.; Bu, L.; Jiang, X.; Lin, L.; Granger, A.; Moretti, A.; Caron, L.; Wu, X.; Clarke, J.; Taketo, M.M.; Laugwitz, K.L.; Moon, R.T.; Gruber, P.; Evans, S.M.; Ding, S.; Chien, K.R. "The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway.". Cell Stem Cell. 1(2): 165-179. (2007). (PMID: 18371348).
Moretti, A.; Caron, L.; Nakano, A.; Lam, J.T.; Bernshausen, A.; Chen, Y.; Qyang, Y.; Bu, L.; Sasaki, M.; Martin-Puig, S.; Sun, Y.; Evans, S.M.; Laugwitz, K.L.; Chien, K.R. "Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification.". Cell. 127(6): 1151-1165. (2006). (PMID: 17123592).
Temes, E.; Martín-Puig, S.; Acosta-Iborra, B.; Castellanos, M.C.; Feijoo-Cuaresma, M.; Olmos, G.; Aragonés, J.; Landazuri, M.O. "Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase.". J Biol Chem. 280(25): 24238-24244. (2005). (PMID: 15849364).
Martín-Puig, S.; Temes, E.; Olmos, G.; Jones, D.R.; Aragonés, J.; Landázuri, M.O. "Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms.". J Biol Chem. 279(10): 9504-9511. (2004). (PMID: 14681229).
Temes, E.; Martín-Puig, S.; Aragonés, J.; Jones, D.R.; Olmos, G.; Mérida, I.; Landázuri, M.O. "Role of diacylglycerol induced by hypoxia in the regulation of HIF-1alpha activity.". Biochem Biophys Res Commun. 315(1): 44-50. (2004). (PMID: 15013423).
del Peso, L.; Castellanos, M.C.; Temes, E.; Martin-Puig, S.; Cuevas, Y.; Olmos, G.; Landazuri, M.O. "The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen.". J. Biol. Chem.. 278(49): 48690-48695. (2003). (PMID: 14506252).
Cuevas, Y.; Hernández-Alcoceba, R.; Aragones, J.; Naranjo-Suárez, S.; Castellanos, M.C.; Esteban, M.A.; Martín-Puig, S.; Landazuri, M.O.; del Peso, L. "Specific oncolytic effect of a new hypoxia-inducible factor-dependent replicative adenovirus on von Hippel-Lindau-defective renal cell carcinomas.". Cancer Res.. 63(20): 6877-6884. (2003). (PMID: 14583486).
Aragonés, J.; Jones, D.R.; Martin, S.; San Juan, M.A.; Alfranca, A.; Vidal, F.; Vara, A.; Mérida, I.; Landázuri, M.O. "Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension.". J Biol Chem. 276(13): 10548-10555. (2001). (PMID: 11136721).
Instituto de Investigaciones Biomédicas "Alberto Sols"
C/Arturo Duperier 4. 28029 Madrid. (Spain)
Tel +(34) 91 585 4400 // Fax +(34) 91 558 4401
Email:Info