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PUBLICACIONES

 

 

spacerTrabajos Publicados por Ana Ramírez de Molina
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  1. Blanco, R.; Gómez de Cedrón, M.; Gámez-Reche, L.; Martín-Leal, A.; González-Martín, A.; Lacalle, R.A.; Ramírez de Molina, A.; Mañes, S. "The Chemokine Receptor CCR5 Links Memory CD4+ T Cell Metabolism to T Cell Antigen Receptor Nanoclustering.". Front Immunol. 12(): 722320. (2021). (PMID: 34950130).
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  2. Garranzo-Asensio, M.; Guzmán-Aránguez, A.; Povés, C.; Fernández-Aceñero, M.J.; Montero-Calle, A.; Ceron, M.Á.; Fernandez-Diez, S.; Rodríguez, N.; Gómez de Cedrón, M.; Ramírez de Molina, A.; Domínguez, G.; Barderas, R. "The specific seroreactivity to ∆Np73 isoforms shows higher diagnostic ability in colorectal cancer patients than the canonical p73 protein.". Sci Rep. 9(1): 13547. (2019). (PMID: 31537884).
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  3. Gallego-Ortega, D.; Ramirez de Molina, A.; Ramos, M.A.; Valdes-Mora, F.; Barderas, M.G.; Sarmentero-Estrada, J.; Lacal, J.C. "Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment.". PLoS ONE. 4(11): e7819. (2009). (PMID: 19915674).
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  4. Bañez-Coronel, M.; Ramírez de Molina, A.; Rodríguez-González, A.; Sarmentero, J.; Ramos, M.A.; García-Cabezas, M.A.; García-Oroz, L.; Lacal, J.C. "Choline kinase alpha depletion selectively kills tumoral cells.". Curr Cancer Drug Targets. 8(8): 709-719. (2008). (PMID: 19075594).
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  5. Gallego-Ortega, D.; Ramirez De Molina, A.; Gutierrez, R.; Ramos, M.A.; Sarmentero, J.; Cejas, P.; Nistal, M.; González Barón, M.; Lacal, J.C. "Generation and characterization of monoclonal antibodies against choline kinase alpha and their potential use as diagnostic tools in cancer.". Int. J. Oncol.. 29(2): 335-340. (2006). (PMID: 16820874).
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  6. Matter, C.M.; Wyss, M.T.; Meier, P.; Späth, N.; von Lukowicz, T.; Lohmann, C.; Weber, B.; Ramirez de Molina, A.; Lacal, J.C.; Ametamey, S.M.; von Schulthess, G.K.; Lüscher, T.F.; Kaufmann, P.A.; Buck, A. "18F-choline images murine atherosclerotic plaques ex vivo.". Arterioscler. Thromb. Vasc. Biol.. 26(3): 584-589. (2006). (PMID: 16357314).
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  7. Al-Saffar, N.M.; Troy, H.; Ramírez de Molina, A.; Jackson, L.E.; Madhu, B.; Griffiths, J.R.; Leach, M.O.; Workman, P.; Lacal, J.C.; Judson, I.R.; Chung, Y.L. "Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.". Cancer Res. 66(1): 427-434. (2006). (PMID: 16397258).
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  8. Rodríguez-González, A.; Ramirez de Molina, A.; Fernández, F.; Lacal, J.C. "Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of action.". Oncogene. 23(50): 8247-8259. (2004). (PMID: 15378008).
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  9. Conejo-García, A.; Báñez-Coronel, M.; Sánchez-Martín, R.M.; Rodríguez-González, A.; Ramos, A.; Ramírez de Molina, A.; Espinosa, A.; Gallo, M.A.; Campos, J.M.; Lacal, J.C. "Influence of the linker in bispyridium compounds on the inhibition of human choline kinase.". J. Med. Chem.. 47(22): 5433-5440. (2004). (PMID: 15481981).
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  10. Ramírez de Molina, A.; Báñez-Coronel, M.; Gutiérrez, R.; Rodríguez-González, A.; Olmeda, D.; Megías, D.; Lacal, J.C. "Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression.". Cancer Res.. 64(18): 6732-6739. (2004). (PMID: 15374991).
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  11. Ramírez de Molina, A.; Rodríguez-González, A.; Lacal, J.C. "From Ras signalling to ChoK inhibitors: a further advance in anticancer drug design.". Cancer Lett.. 206(2): 137-148. (2004). (PMID: 15013519).
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  12. Rodríguez-González, A.; Ramírez de Molina, A.; Fernández, F.; Ramos, M.A.; del Carmen Núñez, M.; Campos, J.; Lacal, J.C. "Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.". Oncogene. 22(55): 8803-8812. (2003). (PMID: 14654777).
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  13. Lucas, L.; Penalva, V.; Ramírez de Molina, A.; Del Peso, L.; Lacal, J.C. "Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1.". Int. J. Oncol.. 21(3): 477-485. (2002). (PMID: 12168089).
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  14. Ramírez de Molina, A.; Rodríguez-González, A.; Gutiérrez, R.; Martínez-Piñeiro, L.; Sánchez, J.; Bonilla, F.; Rosell, R.; Lacal, J. "Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers.". Biochem. Biophys. Res. Commun.. 296(3): 580-583. (2002). (PMID: 12176020).
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  15. Ramírez de Molina, A.; Gutiérrez, R.; Ramos, M.A.; Silva, J.M.; Silva, J.; Bonilla, F.; Sánchez, J.J.; Lacal, J.C. "Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.". Oncogene. 21(27): 4317-4322. (2002). (PMID: 12082619).
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  16. Ramírez de Molina, A.; Penalva, V.; Lucas, L.; Lacal, J.C. "Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K.". Oncogene. 21(6): 937-946. (2002). (PMID: 11840339).
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  17. Casanova, M.L.; Bravo, A.; Ramírez, A.; Morreale de Escobar, G.; Were, F.; Merlino, G.; Vidal, M.; Jorcano, J.L. "Exocrine pancreatic disorders in transsgenic mice expressing human keratin 8.". J. Clin. Invest.. 103(11): 1587-1595. (1999). (PMID: 10359568).
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