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PUBLICACIONES

 

 

spacerTrabajos Publicados por Wolfgang Alexander Link Grosslinger
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  1. Link, W.; Ferreira, B.I. "FOXO Transcription Factors: A Brief Overview.". Methods Mol Biol. 2871(): 1-8. (2025). (PMID: 39565573).
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  2. Jimenez, L.; Domínguez, L.; Amenabar, C.; Serrão, G.; Link, W.; Ferreira, B.I.; Santos, B. "Immunocytochemistry-Based Detection of FOXO Isoforms in Human Cancer and Fibroblasts.". Methods Mol Biol. 2871(): 171-176. (2025). (PMID: 39565588).
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  3. Jimenez, L.; Grenho, I.; Santos, B.; Serrão, G.; Mayoral-Varo, V.; Link, W.; Ferreira, B.I. "Measuring FOXO Activity by Using qPCR-Based Expression Analysis of FOXO Target Genes.". Methods Mol Biol. 2871(): 33-43. (2025). (PMID: 39565576).
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  4. Amenabar, C.; Jimenez, L.; Mourato, C.; Mayoral-Varo, V.; Megías, D.; Ferreira, B.I.; Link, W. "Multiplexed Dual-Color Fluorescence-Based Distinction Between Nuclear Trapping and Translocation of FOXO3.". Methods Mol Biol. 2871(): 163-170. (2025). (PMID: 39565587).
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  5. Santos, B.; Orea-Soufi, A.; Mayoral-Varo, V.; Link, W.; Jimenez, L. "Reporter Gene Assays to Measure FOXO-Specific Transcriptional Activity.". Methods Mol Biol. 2871(): 45-53. (2025). (PMID: 39565577).
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  6. Santos, B.F.; Grenho, I.; Martel, P.J.; Ferreira, B.I.; Link, W. "Correction: FOXO family isoforms.". Cell Death Dis. 14(12): 797. (2023). (PMID: 38057340).
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  7. Santos, B.F.; Grenho, I.; Martel, P.J.; Ferreira, B.I.; Link, W. "FOXO family isoforms.". Cell Death Dis. 14(10): 702. (2023). (PMID: 37891184).
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  8. Velasco, G.; Link, W. "Pseudokinases, Tribbles Proteins and Cancer.". Cancers (Basel). 15(14): . (2023). (PMID: 37509210).
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  9. De Sousa-Coelho, A.L.; Gacias, M.; O'Neill, B.T.; Relat, J.; Link, W.; Haro, D.; Marrero, P.F. "FOXO1 represses PPARα-Mediated induction of FGF21 gene expression.". Biochem Biophys Res Commun. 644(): 122-129. (2023). (PMID: 36640666).
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  10. Jimenez, L.; Mayoral-Varo, V.; Amenábar, C.; Ortega, J.; Sequeira, J.G.N.; Machuqueiro, M.; Mourato, C.; Silvestri, R.; Angeli, A.; Carta, F.; Supuran, C.T.; Megías, D.; Ferreira, B.I.; Link, W. "Multiplexed cellular profiling identifies an organoselenium compound as an inhibitor of CRM1-mediated nuclear export.". Traffic. (): . (2022). (PMID: 36353954).
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  11. Orea-Soufi, A.; Paik, J.; Bragança, J.; Donlon, T.A.; Willcox, B.J.; Link, W. "FOXO transcription factors as therapeutic targets in human diseases.". Trends Pharmacol Sci. (): . (2022). (PMID: 36280450).
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  12. Jimenez, L.; Amenabar, C.; Mayoral-Varo, V.; Mackenzie, T.A.; Ramos, M.C.; Silva, A.; Calissi, G.; Grenho, I.; Blanco-Aparicio, C.; Pastor, J.; Megías, D.; Ferreira, B.I.; Link, W. "mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity.". Molecules. 27(17): . (2022). (PMID: 36080182).
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  13. De Sousa-Coelho, A.L.; Aureliano, M.; Fraqueza, G.; Serrão, G.; Gonçalves, J.; Sánchez-Lombardo, I.; Link, W.; Ferreira, B.I. "Decavanadate and metformin-decavanadate effects in human melanoma cells.". J Inorg Biochem. 235(): 111915. (2022). (PMID: 35834898).
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  14. Faleiro, I.; Roberto, V.P.; Demirkol Canli, S.; Fraunhoffer, N.A.; Iovanna, J.; Gure, A.O.; Link, W.; Castelo-Branco, P. "DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study.". Cancers (Basel). 13(24): . (2021). (PMID: 34944974).
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  15. Passirani, C.; Vessières, A.; La Regina, G.; Link, W.; Silvestri, R. "Modulating undruggable targets to overcome cancer therapy resistance.". Drug Resist Updat. 60(): 100788. (2021). (PMID: 35168144).
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  16. Jimenez, L.; Silva, A.; Calissi, G.; Grenho, I.; Monteiro, R.; Mayoral-Varo, V.; Blanco-Aparicio, C.; Pastor, J.; Bustos, V.; Bracher, F.; Megías, D.; Ferreira, B.I.; Link, W. "Screening health-promoting compounds for their capacity to induce the activity of FOXO3.". J Gerontol A Biol Sci Med Sci. (): . (2021). (PMID: 34508571).
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  17. Link, W.; Ilardi, G.; Zannetti, A. "Editorial: Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression.". Front Oncol. 11(): 730815. (2021). (PMID: 34485160).
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  18. Ferreira, B.I.; Santos, B.; Link, W.; De Sousa-Coelho, A.L. "Tribbles Pseudokinases in Colorectal Cancer.". Cancers (Basel). 13(11): . (2021). (PMID: 34198908).
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  19. Mayoral-Varo, V.; Jiménez, L.; Link, W. "The Critical Role of TRIB2 in Cancer and Therapy Resistance.". Cancers (Basel). 13(11): . (2021). (PMID: 34070799).
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  20. Pérez-Beltrán, C.H.; García-Guzmán, J.J.; Ferreira, B.; Estévez-Hernández, O.; López-Iglesias, D.; Cubillana-Aguilera, L.; Link, W.; Stănică, N.; Rosa da Costa, A.M.; Palacios-Santander, J.M. "One-minute and green synthesis of magnetic iron oxide nanoparticles assisted by design of experiments and high energy ultrasound: Application to biosensing and immunoprecipitation.". Mater Sci Eng C Mater Biol Appl. 123(): 112023. (2021). (PMID: 33812640).
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  21. Machado, S.; Silva, A.; De Sousa-Coelho, A.L.; Duarte, I.; Grenho, I.; Santos, B.; Mayoral-Varo, V.; Megias, D.; Sánchez-Cabo, F.; Dopazo, A.; Ferreira, B.I.; Link, W. "Harmine and Piperlongumine Revert TRIB2-Mediated Drug Resistance.". Cancers (Basel). 12(12): . (2020). (PMID: 33316942).
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  22. Calissi, G.; Lam, E.W.; Link, W. "Therapeutic strategies targeting FOXO transcription factors.". Nat Rev Drug Discov. (): . (2020). (PMID: 33173189).
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  23. Ferreira, B.I.; Cautain, B.; Grenho, I.; Link, W. "Small Molecule Inhibitors of CRM1.". Front Pharmacol. 11(): 625. (2020). (PMID: 32574233).
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  24. Jacinto, F.V.; Link, W.; Ferreira, B.I. "CRISPR/Cas9-mediated genome editing: From basic research to translational medicine.". J. Cell. Mol. Med.. (): . (2020). (PMID: 32096600).
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  25. Barradas, M.; Link, W.; Megias, D.; Fernandez-Marcos, P.J. "High-Throughput Image-Based Screening to Identify Chemical Compounds Capable of Activating FOXO.". Methods Mol. Biol.. 1890(): 151-161. (2019). (PMID: 30414152).
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  26. Link, W. "Introduction to FOXO Biology.". Methods Mol. Biol.. 1890(): 1-9. (2019). (PMID: 30414140).
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  27. Henriques, V.; Machado, S.; Link, W.; Ferreira, B.I. "Monitoring the Transcriptional Activity of FOXO Transcription Factors by Analyzing their Target Genes.". Methods Mol. Biol.. 1890(): 103-113. (2019). (PMID: 30414148).
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  28. Machado, S.; Raposo, C.; Ferreira, B.I.; Link, W. "Image-based Identification of Chemical Compounds Capable of Trapping FOXO in the Cell Nucleus.". Methods Mol. Biol.. 1890(): 163-170. (2019). (PMID: 30414153).
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  29. Henriques, V.; Martins, T.; Link, W.; Ferreira, B.I. "The Emerging Therapeutic Landscape of Advanced Melanoma.". Curr Pharm Des. 24(5): 549-558. (2018). (PMID: 29366407).
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  30. Link, W. "Knowledge-based drug discovery intensifies private appropriation of publicly financed research.". Lancet Oncol.. 19(8): 1017-1018. (2018). (PMID: 30102212).
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  31. Link, W.; Fernandez-Marcos, P.J. "FOXO transcription factors at the interface of metabolism and cancer.". Int J Cancer. 141(12): 2379-2391. (2017). (PMID: 28631330).
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  32. Link, W. "Immunology: Mind the immuno-connection gap.". Nat Chem Biol. 13(6): 572-573. (2017). (PMID: 28437396).
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  33. Hill, R.; Madureira, P.A.; Ferreira, B.; Baptista, I.; Machado, S.; Colaço, L.; Dos Santos, M.; Liu, N.; Dopazo, A.; Ugurel, S.; Adrienn, A.; Kiss-Toth, E.; Isbilen, M.; Gure, A.O.; Link, W. "TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT.". Nat Commun. 8(): 14687. (2017). (PMID: 28276427).
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  34. Ferreira, B.I.; Lie, M.K.; Engelsen, A.S.T.; Machado, S.; Link, W.; Lorens, J.B. "Adaptive mechanisms of resistance to anti-neoplastic agents.". Medchemcomm. 8(1): 53-66. (2017). (PMID: 30108690).
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  35. Cautain, B.; Castillo, F.; Musso, L.; Ferreira, B.I.; de Pedro, N.; Rodriguez Quesada, L.; Machado, S.; Vicente, F.; Dallavalle, S.; Link, W. "Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling.". PLoS One. 11(12): e0167491. (2016). (PMID: 27936162).
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  36. Ferreira, B.I.; Hill, R.; Link, W. "Special Review: Caught in the Crosshairs: Targeted Drugs and Personalized Medicine.". Cancer J. 21(6): 441-447. (2016). (PMID: 26588674).
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  37. Martins, R.; Lithgow, G.J.; Link, W. "Long live FOXO: unraveling the role of FOXO proteins in aging and longevity.". Aging Cell. 15(2): 196-207. (2016). (PMID: 26643314).
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  38. Tarrado-Castellarnau, M.; Cortés, R.; Zanuy, M.; Tarragó-Celada, J.; Polat, I.H.; Hill, R.; Fan, T.W.; Link, W.; Cascante, M. "Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition.". Pharmacol Res. 102(): 218-234. (2015). (PMID: 26375988).
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  39. Cautain, B.; de Pedro, N.; Reyes, F.; Link, W. "Image-based identification of nuclear export inhibitors from natural products.". Methods Mol Biol. 1270(): 307-319. (2015). (PMID: 25702126).
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  40. Link, W. "Tribbles breaking bad: TRIB2 suppresses FOXO and acts as an oncogenic protein in melanoma.". Biochem Soc Trans. 43(5): 1085-1088. (2015). (PMID: 26517928).
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  41. Hill, R.; Kalathur, R.K.; Colaço, L.; Brandão, R.; Ugurel, S.; Futschik, M.; Link, W. "TRIB2 as a biomarker for diagnosis and progression of melanoma.". Carcinogenesis. 36(4): 469-477. (2015). (PMID: 25586991).
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  42. Cautain, B.; Hill, R.; de Pedro, N.; Link, W. "Components and regulation of nuclear transport processes.". FEBS J. 282(3): 445-462. (2015). (PMID: 25429850).
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  43. Mori, M.; Vignaroli, G.; Cau, Y.; Dinić, J.; Hill, R.; Rossi, M.; Colecchia, D.; Pešić, M.; Link, W.; Chiariello, M.; Ottmann, C.; Botta, M. "Discovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693.". ChemMedChem. 9(5): 973-983. (2014). (PMID: 24715717).
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  44. Cortés, R.; Tarrado-Castellarnau, M.; Talancón, D.; López, C.; Link, W.; Ruiz, D.; Centelles, J.J.; Quirante, J.; Cascante, M. "A novel cyclometallated Pt(II)-ferrocene complex induces nuclear FOXO3a localization and apoptosis and synergizes with cisplatin to inhibit lung cancer cell proliferation.". Metallomics. 6(3): 622-633. (2014). (PMID: 24492855).
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  45. Cautain, B.; de Pedro, N.; Murillo Garzón, V.; Muñoz de Escalona, M.; González Menéndez, V.; Tormo, J.R.; Martin, J.; El Aouad, N.; Reyes, F.; Asensio, F.; Genilloud, O.; Vicente, F.; Link, W. "High-content screening of natural products reveals novel nuclear export inhibitors.". J Biomol Screen. 19(1): 57-65. (2014). (PMID: 24045581).
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  46. Hill, R.; Cautain, B.; de Pedro, N.; Link, W. "Targeting nucleocytoplasmic transport in cancer therapy.". Oncotarget. 5(1): 11-28. (2014). (PMID: 24429466).
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  47. Zanella, F.; Dos Santos, N.R.; Link, W. "Moving to the core: spatiotemporal analysis of Forkhead box O (FOXO) and nuclear factor-κB (NF-κB) nuclear translocation.". Traffic. 14(3): 247-258. (2013). (PMID: 23231504).
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  48. Granda, T.G.; Cebrián, D.; Martínez, S.; Anguita, P.V.; López, E.C.; Link, W.; Merino, T.; Pastor, J.; Serelde, B.G.; Peregrina, S.; Palacios, I.; Albarran, M.I.; Cebriá, A.; Lorenzo, M.; Alonso, P.; Fominaya, J.; López, A.R.; Bischoff, J.R. "Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases.". Invest New Drugs. 31(1): 66-76. (2013). (PMID: 22623067).
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  49. Evensen, L.; Link, W.; Lorens, J.B. "Image-based high-throughput screening for inhibitors of angiogenesis.". Methods Mol Biol. 931(): 139-151. (2013). (PMID: 23027002).
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  50. Link, W. "Nuclear accumulation of β-catenin and forkhead box O3a in colon cancer: Dangerous liaison.". World J Biol Chem. 3(9): 175-179. (2012). (PMID: 23024836).
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  51. Martínez González, S.; Hernández, A.I.; Varela, C.; Lorenzo, M.; Ramos-Lima, F.; Cendón, E.; Cebrián, D.; Aguirre, E.; Gomez-Casero, E.; Albarrán, M.I.; Alfonso, P.; García-Serelde, B.; Mateos, G.; Oyarzabal, J.; Rabal, O.; Mulero, F.; Gonzalez-Granda, T.; Link, W.; Fominaya, J.; Barbacid, M.; Bischoff, J.R.; Pizcueta, P.; Blanco-Aparicio, C.; Pastor, J. "Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR.". Bioorg Med Chem Lett. 22(16): 5208-5214. (2012). (PMID: 22819764).
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  52. Martínez González, S.; Hernández, A.I.; Varela, C.; Rodríguez-Arístegui, S.; Lorenzo, M.; Rodríguez, A.; Rivero, V.; Martín, J.I.; Saluste, C.G.; Ramos-Lima, F.; Cendón, E.; Cebrián, D.; Aguirre, E.; Gomez-Casero, E.; Albarrán, M.; Alfonso, P.; García-Serelde, B.; Oyarzabal, J.; Rabal, O.; Mulero, F.; Gonzalez-Granda, T.; Link, W.; Fominaya, J.; Barbacid, M.; Bischoff, J.R.; Pizcueta, P.; Pastor, J. "Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor.". Bioorg Med Chem Lett. 22(10): 3460-3466. (2012). (PMID: 22520259).
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  53. Martínez González, S.; Hernández, A.I.; Varela, C.; Rodríguez-Arístegui, S.; Alvarez, R.M.; García, A.B.; Lorenzo, M.; Rivero, V.; Oyarzabal, J.; Rabal, O.; Bischoff, J.R.; Albarrán, M.; Cebriá, A.; Alfonso, P.; Link, W.; Fominaya, J.; Pastor, J. "Imidazo[1,2-a]pyrazines as novel PI3K inhibitors.". Bioorg Med Chem Lett. 22(5): 1874-1878. (2012). (PMID: 22325943).
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  54. Kauselmann, G.; Dopazo, A.; Link, W. "Identification of disease-relevant genes for molecularly-targeted drug discovery.". Curr Cancer Drug Targets. 12(1): 1-13. (2012). (PMID: 22165964).
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  55. Hung, M.C.; Link, W. "Protein localization in disease and therapy.". J Cell Sci. 124(Pt 20): 3381-3392. (2011). (PMID: 22010196).
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  56. Link, W. "The therapeutic potential of FOXO proteins.". Curr Drug Targets. 12(9): 1232-1234. (2011). (PMID: 21443469).
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  57. Link, W. "Context-dependent therapeutic potential of FOXO proteins in oral squamous cell carcinoma.". Oral Oncol. 47(4): 229-230. (2011). (PMID: 21376658).
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  58. Evensen, L.; Link, W.; Lorens, J.B. "Imaged-based high-throughput screening for anti-angiogenic drug discovery.". Curr Pharm Des. 16(35): 3958-3963. (2010). (PMID: 21158729).
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  59. Zanella, F.; Lorens, J.B.; Link, W. "High content screening: seeing is believing.". Trends Biotechnol. 28(5): 237-245. (2010). (PMID: 20346526).
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  60. Zanella, F.; Renner, O.; García, B.; Callejas, S.; Dopazo, A.; Peregrina, S.; Carnero, A.; Link, W. "Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells.". Oncogene. 29(20): 2973-2982. (2010). (PMID: 20208562).
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  61. Rabal, O.; Link, W.; Serelde, B.G.; Bischoff, J.R.; Oyarzabal, J. "An integrated one-step system to extract, analyze and annotate all relevant information from image-based cell screening of chemical libraries.". Mol Biosyst. 6(4): 711-720. (2010). (PMID: 20237649).
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  62. Zanella, F.; Link, W.; Carnero, A. "Understanding FOXO, new views on old transcription factors.". Curr Cancer Drug Targets. 10(2): 135-146. (2010). (PMID: 20088800).
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  63. Evensen, L.; Micklem, D.R.; Link, W.; Lorens, J.B. "A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery.". Cytometry A. 77(1): 41-51. (2010). (PMID: 19834964).
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  64. Link, W.; Oyarzabal, J.; Serelde, B.G.; Albarran, M.I.; Rabal, O.; Cebriá, A.; Alfonso, P.; Fominaya, J.; Renner, O.; Peregrina, S.; Soilán, D.; Ceballos, P.A.; Hernández, A.I.; Lorenzo, M.; Pevarello, P.; Granda, T.G.; Kurz, G.; Carnero, A.; Bischoff, J.R. "Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases.". J Biol Chem. 284(41): 28392-28400. (2009). (PMID: 19690175).
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  65. Zanella, F.; Rosado, A.; Garcia, B.; Carnero, A.; Link, W. "Using multiplexed regulation of luciferase activity and GFP translocation to screen for FOXO modulators.". BMC Cell Biol. 10(): 14. (2009). (PMID: 19243599).
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  66. Zanella, F.; Rosado, A.; García, B.; Carnero, A.; Link, W. "Chemical genetic analysis of FOXO nuclear-cytoplasmic shuttling by using image-based cell screening.". Chembiochem. 9(14): 2229-2237. (2008). (PMID: 18756565).
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  67. Carnero, A.; Blanco-Aparicio, C.; Renner, O.; Link, W.; Leal, J.F. "The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.". Curr Cancer Drug Targets. 8(3): 187-198. (2008). (PMID: 18473732).
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  68. Rosado, A.; Zanella, F.; Garcia, B.; Carnero, A.; Link, W. "A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling.". PLoS One. 3(3): e1823. (2008). (PMID: 18350159).
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  69. Guijarro, M.V.; Link, W.; Rosado, A.; Leal, J.F.; Carnero, A. "MAP17 inhibits Myc-induced apoptosis through PI3K/AKT pathway activation.". Carcinogenesis. 28(12): 2443-2450. (2007). (PMID: 17675338).
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  70. Liebel, U.; Link, W. "Meeting report: trends and challenges in high content analysis.". Biotechnol J. 2(8): 938-940. (2007). (PMID: 17680709).
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  71. Zanella, F.; Rosado, A.; Blanco, F.; Henderson, B.R.; Carnero, A.; Link, W. "An HTS approach to screen for antagonists of the nuclear export machinery using high content cell-based assays.". Assay Drug Dev Technol. 5(3): 333-341. (2007). (PMID: 17638533).
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  72. Link, W.; Rosado, A.; Fominaya, J.; Thomas, J.E.; Carnero, A. "Membrane localization of all class I PI 3-kinase isoforms suppresses c-Myc-induced apoptosis in Rat1 fibroblasts via Akt.". J Cell Biochem. 95(5): 979-989. (2005). (PMID: 15838873).
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  73. Mellstrom, B.; Torres, B.; Link, W.A.; Naranjo, J.R. "The BDNF gene: exemplifying complexity in Ca2+ -dependent gene expression.". Crit Rev Neurobiol. 16(1-2): 43-49. (2004). (PMID: 15581398).
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  74. Link, W.A.; Ledo, F.; Torres, B.; Palczewska, M.; Madsen, T.M.; Savignac, M.; Albar, J.P.; Mellström, B.; Naranjo, J.R. "Day-night changes in downstream regulatory element antagonist modulator/potassium channel interacting protein activity contribute to circadian gene expression in pineal gland.". J Neurosci. 24(23): 5346-5355. (2004). (PMID: 15190107).
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  75. Moneo, V.; del Valle Guijarro, M.; Link, W.; Carnero, A. "Overexpression of cyclin D1 inhibits TNF-induced growth arrest.". J Cell Biochem. 89(3): 484-499. (2003). (PMID: 12761882).
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  76. Sanz, C.; Mellstrom, B.; Link, W.A.; Naranjo, J.R.; Fernandez-Luna, J.L. "Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells.". EMBO J. 20(9): 2286-2292. (2001). (PMID: 11331593).
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  77. Ledo, F.; Carrión, A.M.; Link, W.A.; Mellström, B.; Naranjo, J.R. "DREAM-alphaCREM interaction via leucine-charged domains derepresses downstream regulatory element-dependent transcription.". Mol Cell Biol. 20(24): 9120-9126. (2000). (PMID: 11094064).
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  78. Ledo, F.; Link, W.A.; Carrión, A.M.; Echeverria, V.; Mellström, B.; Naranjo, J.R. "The DREAM-DRE interaction: key nucleotides and dominant negative mutants.". Biochim Biophys Acta. 1498(2-3): 162-168. (2000). (PMID: 11108959).
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  79. Link, W.A.; Kauselmann, G.; Mellström, B.; Kuhl, D.; Naranjo, J.R. "Induction of glycerol phosphate dehydrogenase gene expression during seizure and analgesia.". J Neurochem. 75(4): 1419-1428. (2000). (PMID: 10987821).
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  80. Carrión, A.M.; Link, W.A.; Ledo, F.; Mellström, B.; Naranjo, J.R. "DREAM is a Ca2+-regulated transcriptional repressor.". Nature. 398(6722): 80-84. (1999). (PMID: 10078534).
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  81. Link, W.; Konietzko, U.; Kauselmann, G.; Krug, M.; Schwanke, B.; Frey, U.; Kuhl, D. "Somatodendritic expression of an immediate early gene is regulated by synaptic activity.". Proc Natl Acad Sci U S A. 92(12): 5734-5738. (1995). (PMID: 7777577).
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Instituto de Investigaciones Biomédicas "Alberto Sols"
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