INVESTIGACIÓN

 
  • Grupos de Investigación
  • Unidades de Investigación
  • Memoria Cientifíca
  • Publicaciones
espacio

 

PUBLICACIONES

 

 

spacerTrabajos Publicados por Lourdes Rodríguez de la Rosa
spacer
  1. García-Mato, Á.; Cervantes, B.; Rodríguez-de la Rosa, L.; Varela-Nieto, I. "IGF-1 Controls Metabolic Homeostasis and Survival in HEI-OC1 Auditory Cells through AKT and mTOR Signaling.". Antioxidants (Basel). 12(2): . (2023). (PMID: 36829792).
    spacer

  2. García-Mato, Á.; Cervantes, B.; Murillo-Cuesta, S.; Rodríguez-de la Rosa, L.; Varela-Nieto, I. "Insulin-like Growth Factor 1 Signaling in Mammalian Hearing.". Genes (Basel). 12(10): . (2021). (PMID: 34680948).
    spacer

  3. Varela-Nieto, I.; Murillo-Cuesta, S.; Rodríguez-de la Rosa, L.; Oset-Gasque, M.J.; Marco-Contelles, J. "Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges.". Front Cell Neurosci. 15(): 711269. (2021). (PMID: 34539349).
    spacer

  4. Bermúdez-Muñoz, J.M.; Celaya, A.M.; García-Mato, Á.; Muñoz-Espín, D.; Rodríguez-de la Rosa, L.; Serrano, M.; Varela-Nieto, I. "Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea.". Antioxidants (Basel). 10(9): . (2021). (PMID: 34572983).
    spacer

  5. Celaya, A.M.; Rodríguez-de la Rosa, L.; Bermúdez-Muñoz, J.M.; Zubeldia, J.M.; Romá-Mateo, C.; Avendaño, C.; Pallardó, F.V.; Varela-Nieto, I. "IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss.". Cells. 10(7): . (2021). (PMID: 34359856).
    spacer

  6. Murillo-Cuesta, S.; Celaya, A.M.; Cervantes, B.; Bermúdez-Muñoz, J.M.; Rodríguez-de la Rosa, L.; Contreras, J.; Sánchez-Pérez, I.; Varela-Nieto, I. "Therapeutic efficiency of the APAF-1 antagonist LPT99 in a rat model of cisplatin-induced hearing loss.". Clin Transl Med. 11(4): e363. (2021). (PMID: 33931965).
    spacer

  7. Lassaletta, L.; Calvino, M.; Morales-Puebla, J.M.; Lapunzina, P.; Rodriguez-de la Rosa, L.; Varela-Nieto, I.; Martinez-Glez, V. "Biomarkers in Vestibular Schwannoma-Associated Hearing Loss.". Front Neurol. 10(): 978. (2019). (PMID: 31620068).
    spacer

  8. Partearroyo, T.; Murillo-Cuesta, S.; Vallecillo, N.; Bermúdez-Muñoz, J.M.; Rodríguez-de la Rosa, L.; Mandruzzato, G.; Celaya, A.M.; Zeisel, S.H.; Pajares, M.A.; Varela-Moreiras, G.; Varela-Nieto, I. "Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia.". FASEB J.. 33(5): 5942-5956. (2019). (PMID: 30753104).
    spacer

  9. Celaya, A.M.; Sánchez-Pérez, I.; Bermúdez-Muñoz, J.M.; Rodríguez-de la Rosa, L.; Pintado-Berninches, L.; Perona, R.; Murillo-Cuesta, S.; Varela-Nieto, I. "Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.". Elife. 8(): . (2019). (PMID: 30938680).
    spacer

  10. Fuentes-Santamaría, V.; Alvarado, J.C.; Rodríguez-de la Rosa, L.; Juiz, J.M.; Varela-Nieto, I. "Neuroglial Involvement in Abnormal Glutamate Transport in the Cochlear Nuclei of the Igf1-/- Mouse.". Front Cell Neurosci. 13(): 67. (2019). (PMID: 30881288).
    spacer

  11. Rodríguez-de la Rosa, L.; Lassaletta, L.; Calvino, M.; Murillo-Cuesta, S.; Varela-Nieto, I. "The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss.". Front Aging Neurosci. 9(): 411. (2017). (PMID: 29311900).
    spacer

  12. Arroba, A.I.; Rodríguez-de la Rosa, L.; Murillo-Cuesta, S.; Vaquero-Villanueva, L.; Hurlé, J.M.; Varela-Nieto, I.; Valverde, Á.M. "Autophagy resolves early retinal inflammation in Igf1-deficient mice.". Dis Model Mech. 9(9): 965-974. (2016). (PMID: 27483352).
    spacer

  13. Fuentes-Santamaría, V.; Alvarado, J.C.; Rodríguez-de la Rosa, L.; Murillo-Cuesta, S.; Contreras, J.; Juiz, J.M.; Varela-Nieto, I. "Erratum to: IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei.". Brain Struct Funct. 221(2): 1205. (2016). (PMID: 25416135).
    spacer

  14. Fuentes-Santamaría, V.; Alvarado, J.C.; Rodríguez-de la Rosa, L.; Murillo-Cuesta, S.; Contreras, J.; Juiz, J.M.; Varela-Nieto, I. "IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei.". Brain Struct Funct. 221(2): 709-734. (2016). (PMID: 25378055).
    spacer

  15. de Iriarte Rodríguez, R.; Pulido, S.; Rodríguez-de la Rosa, L.; Magariños, M.; Varela-Nieto, I. "Age-regulated function of autophagy in the mouse inner ear.". Hear. Res.. 330(Pt A): 39-50. (2015). (PMID: 26235979).
    spacer

  16. Rodríguez-de la Rosa, L.; Sánchez-Calderón, H.; Contreras, J.; Murillo-Cuesta, S.; Falagan, S.; Avendaño, C.; Dopazo, J.; Varela-Nieto, I.; Milo, M. "Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays.". Hear. Res.. (): . (2015). (PMID: 26341476).
    spacer

  17. Murillo-Cuesta, S.; Rodríguez-de la Rosa, L.; Contreras, J.; Celaya, A.M.; Camarero, G.; Rivera, T.; Varela-Nieto, I. "Corrigendum: Transforming growth factor β1 inhibition protects from noise-induced hearing loss.". Front Aging Neurosci. 7(): 72. (2015). (PMID: 26005416).
    spacer

  18. López, I.P.; Rodriguez-de la Rosa, L.; Pais, R.S.; Piñeiro-Hermida, S.; Torrens, R.; Contreras, J.; Varela-Nieto, I.; Pichel, J.G. "Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r (fl/fl) double transgenic mice.". Transgenic Res.. 24(2): 279-294. (2015). (PMID: 25238791).
    spacer

  19. Murillo-Cuesta, S.; Rodríguez-de la Rosa, L.; Contreras, J.; Celaya, A.M.; Camarero, G.; Rivera, T.; Varela-Nieto, I. "Transforming growth factor β1 inhibition protects from noise-induced hearing loss.". Front Aging Neurosci. 7(): 32. (2015). (PMID: 25852546).
    spacer

  20. Rodríguez-de la Rosa, L.; López-Herradón, A.; Portal-Núñez, S.; Murillo-Cuesta, S.; Lozano, D.; Cediel, R.; Varela-Nieto, I.; Esbrit, P. "Treatment with N- and C-terminal peptides of parathyroid hormone-related protein partly compensate the skeletal abnormalities in IGF-I deficient mice.". PLoS ONE. 9(2): e87536. (2014). (PMID: 24503961).
    spacer

  21. Varela-Nieto, I.; Murillo-Cuesta, S.; Rodríguez-de la Rosa, L.; Lassatetta, L.; Contreras, J. "IGF-I deficiency and hearing loss: molecular clues and clinical implications.". Pediatr Endocrinol Rev. 10(4): 460-472. (2013). (PMID: 23957197).
    spacer

  22. Rodriguez-de la Rosa, L.; Fernandez-Sanchez, L.; Germain, F.; Murillo-Cuesta, S.; Varela-Nieto, I.; de la Villa, P.; Cuenca, N. "Age-related functional and structural retinal modifications in the Igf1-/- null mouse.". Neurobiol. Dis.. 46(2): 476-485. (2012). (PMID: 22402333).
    spacer

  23. Murillo-Cuesta, S.; Camarero, G.; González-Rodríguez, A.; De La Rosa, L.R.; Burks, D.J.; Avendaño, C.; Valverde, A.M.; Varela-Nieto, I. "Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function.". Mol. Med.. 18(): 260-269. (2012). (PMID: 22160220).
    spacer

  24. Murillo-Cuesta, S.; Rodríguez-de la Rosa, L.; Cediel, R.; Lassaletta, L.; Varela-Nieto, I. "The role of insulin-like growth factor-I in the physiopathology of hearing.". Front Mol Neurosci. 4(): 11. (2011). (PMID: 21845174).
    spacer

  25. Riquelme, R.; Cediel, R.; Contreras, J.; la Rosa Lourdes, R.D.; Murillo-Cuesta, S.; Hernandez-Sanchez, C.; Zubeldia, J.M.; Cerdan, S.; Varela-Nieto, I. "A comparative study of age-related hearing loss in wild type and insulin-like growth factor I deficient mice.". Front Neuroanat. 4(): 27. (2010). (PMID: 20661454).
    spacer

  26. Sanchez-Calderon, H.; Rodriguez-de la Rosa, L.; Milo, M.; Pichel, J.G.; Holley, M.; Varela-Nieto, I. "RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.". PLoS ONE. 5(1): e8699. (2010). (PMID: 20111592).
    spacer

  27. Rodríguez-de la Rosa, L.; Contreras-Rodríguez, J.; Cediel-Algovia, R.; León, Y.; Sánchez-Calderón, H.; Murillo-Cuesta, S.; Riquelme-Galiana, R.; de Diego-Sastre, J.I.; Prim-Espada, M.P.; Varela-Nieto, I.; , . "[Neurotrophic action of insulin-like growth factor-I in the inner ear].". Rev Neurol. 45(4): 245-250. (2008). (PMID: 17668408).
    spacer

 

 

 

 

 

Instituto de Investigaciones Biomédicas "Alberto Sols"
C/Arturo Duperier 4. 28029 Madrid. (Spain)
Tel +(34) 91 585 4400 // Fax +(34) 91 558 4401
Email:Info