Olmeda, D.; Cerezo-Wallis, D.; Castellano-Sanz, E.; García-Silva, S.; Peinado, H.; Soengas, M.S. "Physiological models for in vivo imaging and targeting the lymphatic system: Nanoparticles and extracellular vesicles.". Adv Drug Deliv Rev. 175(): 113833. (2021). (PMID: 34147531).
Wurth, L.; Papasaikas, P.; Olmeda, D.; Bley, N.; Calvo, G.T.; Guerrero, S.; Cerezo-Wallis, D.; Martinez-Useros, J.; García-Fernández, M.; Hüttelmaier, S.; Soengas, M.S.; Gebauer, F. "UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis.". Cancer Cell. 30(5): 694-707. (2016). (PMID: 27908735).
García-Fernández, M.; Karras, P.; Checinska, A.; Cañón, E.; Calvo, G.T.; Gómez-López, G.; Cifdaloz, M.; Colmenar, A.; Espinosa-Hevia, L.; Olmeda, D.; Soengas, M.S. "Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5.". Autophagy. 12(10): 1776-1790. (2016). (PMID: 27464255).
Martínez-Iglesias, O.; Olmeda, D.; Alonso-Merino, E.; Gómez-Rey, S.; González-López, A.M.; Luengo, E.; Soengas, M.S.; Palacios, J.; Regadera, J.; Aranda, A. "The nuclear corepressor 1 and the thyroid hormone receptor β suppress breast tumor lymphangiogenesis.". Oncotarget. (): . (2016). (PMID: 27806339).
Martinez-Corral, I.; Stanczuk, L.; Frye, M.; Ulvmar, M.H.; Diéguez-Hurtado, R.; Olmeda, D.; Makinen, T.; Ortega, S. "Vegfr3-CreER (T2) mouse, a new genetic tool for targeting the lymphatic system.". Angiogenesis. 19(3): 433-445. (2016). (PMID: 26993803).
Maes, H.; Olmeda, D.; Soengas, M.S.; Agostinis, P. "Vesicular trafficking mechanisms in endothelial cells as modulators of the tumor vasculature and targets of antiangiogenic therapies.". FEBS J. 283(1): 25-38. (2016). (PMID: 26443003).
Díaz-López, A.; Díaz-Martín, J.; Moreno-Bueno, G.; Cuevas, E.P.; Santos, V.; Olmeda, D.; Portillo, F.; Palacios, J.; Cano, A. "Zeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMT.". Int. J. Cancer. 136(4): E62-73. (2015). (PMID: 25178837).
Alonso-Curbelo, D.; Riveiro-Falkenbach, E.; Pérez-Guijarro, E.; Cifdaloz, M.; Karras, P.; Osterloh, L.; Megías, D.; Cañón, E.; Calvo, T.G.; Olmeda, D.; Gómez-López, G.; Graña, O.; Sánchez-Arévalo Lobo, V.J.; Pisano, D.G.; Wang, H.W.; Ortiz-Romero, P.; Tormo, D.; Hoek, K.; Rodríguez-Peralto, J.L.; Joyce, J.A.; Soengas, M.S. "RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway.". Cancer Cell. 26(1): 61-76. (2014). (PMID: 24981740).
Abéngozar, M.A.; de Frutos, S.; Ferreiro, S.; Soriano, J.; Perez-Martinez, M.; Olmeda, D.; Marenchino, M.; Cañamero, M.; Ortega, S.; Megias, D.; Rodriguez, A.; Martínez-Torrecuadrada, J.L. "Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth.". Blood. 119(19): 4565-4576. (2012). (PMID: 22446484).
Martínez-Corral, I.; Olmeda, D.; Diéguez-Hurtado, R.; Tammela, T.; Alitalo, K.; Ortega, S. "In vivo imaging of lymphatic vessels in development, wound healing, inflammation, and tumor metastasis.". Proc Natl Acad Sci U S A. 109(16): 6223-6228. (2012). (PMID: 22474390).
Diéguez-Hurtado, R.; Martín, J.; Martínez-Corral, I.; Martínez, M.D.; Megías, D.; Olmeda, D.; Ortega, S. "A Cre-reporter transgenic mouse expressing the far-red fluorescent protein Katushka.". Genesis. 49(1): 36-45. (2011). (PMID: 21254335).
Raviña, M.; Cubillo, E.; Olmeda, D.; Novoa-Carballal, R.; Fernandez-Megia, E.; Riguera, R.; Sánchez, A.; Cano, A.; Alonso, M.J. "Hyaluronic acid/chitosan-g-poly(ethylene glycol) nanoparticles for gene therapy: an application for pDNA and siRNA delivery.". Pharm. Res.. 27(12): 2544-2555. (2010). (PMID: 20857179).
Olmeda, D.; Montes, A.; Moreno-Bueno, G.; Flores, J.M.; Portillo, F.; Cano, A. "Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines.". Oncogene. 27(34): 4690-4701. (2008). (PMID: 18408755).
Olmeda, D.; Moreno-Bueno, G.; Flores, J.M.; Fabra, A.; Portillo, F.; Cano, A. "SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells.". Cancer Res.. 67(24): 11721-11731. (2007). (PMID: 18089802).
Jordà, M.; Vinyals, A.; Marazuela, A.; Cubillo, E.; Olmeda, D.; Valero, E.; Cano, A.; Fabra, A. "Id-1 is induced in MDCK epithelial cells by activated Erk/MAPK pathway in response to expression of the Snail and E47 transcription factors.". Exp. Cell Res.. 313(11): 2389-2403. (2007). (PMID: 17490644).
Peinado, H.; Olmeda, D.; Cano, A. "Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?". Nat. Rev. Cancer. 7(6): 415-428. (2007). (PMID: 17508028).
Olmeda, D.; Jordá, M.; Peinado, H.; Fabra, A.; Cano, A. "Snail silencing effectively suppresses tumour growth and invasiveness.". Oncogene. 26(13): 1862-1874. (2007). (PMID: 17043660).
Peinado, H.; Del Carmen Iglesias-de la Cruz, M.; Olmeda, D.; Csiszar, K.; Fong, K.S.; Vega, S.; Nieto, M.A.; Cano, A.; Portillo, F. "A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression.". EMBO J. 24(19): 3446-3458. (2005). (PMID: 16096638).
Jordà, M.; Olmeda, D.; Vinyals, A.; Valero, E.; Cubillo, E.; Llorens, A.; Cano, A.; Fabra, A. "Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor.". J Cell Sci. 118(Pt 15): 3371-3385. (2005). (PMID: 16079281).
Ramírez de Molina, A.; Báñez-Coronel, M.; Gutiérrez, R.; Rodríguez-González, A.; Olmeda, D.; Megías, D.; Lacal, J.C. "Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression.". Cancer Res.. 64(18): 6732-6739. (2004). (PMID: 15374991).
Olmeda, D.; Castel, S.; Vilaró, S.; Cano, A. "Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis.". Mol. Biol. Cell. 14(7): 2844-2860. (2003). (PMID: 12857869).
Instituto de Investigaciones Biomédicas "Alberto Sols"
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