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spacerTrabajos Publicados por Silvia González Ramos
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  1. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Castrillo, A.; Boscá, L. "Unraveling the interplay between iron homeostasis, ferroptosis and extramedullary hematopoiesis.". Pharmacol Res. 183(): 106386. (2022). (PMID: 35933006).
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  2. Fernández-García, V.; González-Ramos, S.; Avendaño-Ortiz, J.; Martín-Sanz, P.; Gómez-Coronado, D.; Delgado, C.; Castrillo, A.; Boscá, L. "High-fat diet activates splenic NOD1 and enhances neutrophil recruitment and neutrophil extracellular traps release in the spleen of ApoE-deficient mice.". Cell Mol Life Sci. 79(8): 396. (2022). (PMID: 35789437).
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  3. Fernández-García, V.; González-Ramos, S.; Avendaño-Ortiz, J.; Martín-Sanz, P.; Delgado, C.; Castrillo, A.; Boscá, L. "NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions.". Biomed Pharmacother. 148(): 112769. (2022). (PMID: 35247718).
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  4. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Portillo, F.G.; Laparra, J.M.; Boscá, L. "NOD1 in the interplay between microbiota and gastrointestinal immune adaptations.". Pharmacol Res. (): 105775. (2021). (PMID: 34273489).
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  5. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Laparra, J.M.; Boscá, L. "Beyond classic concepts in thyroid homeostasis: immune system and microbiota.". Mol Cell Endocrinol. (): 111333. (2021). (PMID: 34048865).
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  6. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Laparra, J.M.; Boscá, L. "NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health.". Biomedicines. 9(5): . (2021). (PMID: 34066406).
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  7. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Castrillo, A.; Boscá, L. "Contribution of Extramedullary Hematopoiesis to Atherosclerosis. The Spleen as a Neglected Hub of Inflammatory Cells.". Front Immunol. 11(): 586527. (2020). (PMID: 33193412).
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  8. González-Ramos, S.; Fernández-García, V.; Recalde, M.; Rodríguez, C.; Martínez-González, J.; Andrés, V.; Martín-Sanz, P.; Boscá, L. "Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis .". Cells. 9(9): . (2020). (PMID: 32927803).
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  9. González-Ramos, S.; Paz-García, M.; Fernández-García, V.; Portune, K.J.; Acosta-Medina, E.F.; Sanz, Y.; Castrillo, A.; Martín-Sanz, P.; Obregon, M.J.; Boscá, L. "NOD1 deficiency promotes an imbalance of thyroid hormones and microbiota homeostasis in mice fed high fat diet.". Sci Rep. 10(1): 12317. (2020). (PMID: 32704052).
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  10. Haider, N.; Boscá, L.; Zandbergen, H.R.; Kovacic, J.C.; Narula, N.; González-Ramos, S.; Fernandez-Velasco, M.; Agrawal, S.; Paz-García, M.; Gupta, S.; DeLeon-Pennell, K.; Fuster, V.; Ibañez, B.; Narula, J. "Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction.". J. Am. Coll. Cardiol.. 74(25): 3124-3135. (2019). (PMID: 31856969).
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  11. González-Ramos, S.; Paz-García, M.; Rius, C.; Del Monte-Monge, A.; Rodríguez, C.; Fernández-García, V.; Andrés, V.; Martínez-González, J.; Lasunción, M.A.; Martín-Sanz, P.; Soehnlein, O.; Boscá, L. "Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1.". FASEB J.. 33(3): 3912-3921. (2019). (PMID: 30496704).
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  12. Mojena, M.; Povo-Retana, A.; González-Ramos, S.; Fernández-García, V.; Regadera, J.; Zazpe, A.; Artaiz, I.; Martín-Sanz, P.; Ledo, F.; Boscá, L. "Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells.". Front Oncol. 8(): 328. (2018). (PMID: 30191142).
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  13. Mojena, M.; Pimentel-Santillana, M.; Povo-Retana, A.; Fernández-García, V.; González-Ramos, S.; Rada, P.; Tejedor, A.; Rico, D.; Martín-Sanz, P.; Valverde, A.M.; Boscá, L. "Protection against gamma-radiation injury by protein tyrosine phosphatase 1B.". Redox Biol. 17(): 213-223. (2018). (PMID: 29705509).
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  14. Singh, P.; González-Ramos, S.; Mojena, M.; Rosales-Mendoza, C.E.; Emami, H.; Swanson, J.; Morss, A.; Fayad, Z.A.; Rudd, J.H.; Gelfand, J.; Paz-García, M.; Martín-Sanz, P.; Boscá, L.; Tawakol, A. "GM-CSF Enhances Macrophage Glycolytic Activity In Vitro and Improves Detection of Inflammation In Vivo.". J. Nucl. Med.. 57(9): 1428-1435. (2016). (PMID: 27081166).
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  15. Boscá, L.; González-Ramos, S.; Prieto, P.; Fernández-Velasco, M.; Mojena, M.; Martín-Sanz, P.; Alemany, S. "Metabolic signatures linked to macrophage polarization: from glucose metabolism to oxidative phosphorylation.". Biochem. Soc. Trans.. 43(4): 740-744. (2015). (PMID: 26551722).
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  16. Delgado, C.; Ruiz-Hurtado, G.; Gómez-Hurtado, N.; González-Ramos, S.; Rueda, A.; Benito, G.; Prieto, P.; Zaragoza, C.; Delicado, E.G.; Pérez-Sen, R.; Miras-Portugal, M.T.; Núñez, G.; Boscá, L.; Fernández-Velasco, M. "NOD1, A new player in cardiac function and calcium handling.". Cardiovasc. Res.. (): . (2015). (PMID: 25824149).
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    CONCLUSION
    Our data provide the first evidence that NOD1 activation induces cardiac dysfunction associated with excitation-contraction coupling-impairment through NF-κB activation, and uncover a new proinflammatory player in the regulation of cardiovascular function.

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  17. Fernández-Velasco, M.; González-Ramos, S.; Boscá, L. "Involvement of monocytes/macrophages as key factors in the development and progression of cardiovascular diseases.". Biochem. J.. 458(2): 187-193. (2014). (PMID: 24524191).
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Instituto de Investigaciones Biomédicas "Alberto Sols"
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