Fernández-García, V. ; González-Ramos, S. ; Martín-Sanz, P. ; Castrillo, A. ; Boscá, L. "Unraveling the interplay between iron homeostasis, ferroptosis and extramedullary hematopoiesis." . Pharmacol Res. 183(): 106386. (2022). (PMID: 35933006).
Fernández-García, V. ; González-Ramos, S. ; Avendaño-Ortiz, J.; Martín-Sanz, P. ; Gómez-Coronado, D.; Delgado, C. ; Castrillo, A. ; Boscá, L. "High-fat diet activates splenic NOD1 and enhances neutrophil recruitment and neutrophil extracellular traps release in the spleen of ApoE-deficient mice." . Cell Mol Life Sci. 79(8): 396. (2022). (PMID: 35789437).
Fernández-García, V. ; González-Ramos, S. ; Avendaño-Ortiz, J.; Martín-Sanz, P. ; Delgado, C. ; Castrillo, A. ; Boscá, L. "NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions." . Biomed Pharmacother. 148(): 112769. (2022). (PMID: 35247718).
Fernández-García, V. ; González-Ramos, S. ; Martín-Sanz, P. ; Portillo, F.G.; Laparra, J.M.; Boscá, L. "NOD1 in the interplay between microbiota and gastrointestinal immune adaptations." . Pharmacol Res. (): 105775. (2021). (PMID: 34273489).
Fernández-García, V. ; González-Ramos, S. ; Martín-Sanz, P. ; Laparra, J.M.; Boscá, L. "Beyond classic concepts in thyroid homeostasis: immune system and microbiota." . Mol Cell Endocrinol. (): 111333. (2021). (PMID: 34048865).
Fernández-García, V. ; González-Ramos, S. ; Martín-Sanz, P. ; Laparra, J.M.; Boscá, L. "NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health." . Biomedicines. 9(5): . (2021). (PMID: 34066406).
Fernández-García, V. ; González-Ramos, S. ; Martín-Sanz, P. ; Castrillo, A. ; Boscá, L. "Contribution of Extramedullary Hematopoiesis to Atherosclerosis. The Spleen as a Neglected Hub of Inflammatory Cells." . Front Immunol. 11(): 586527. (2020). (PMID: 33193412).
González-Ramos, S. ; Fernández-García, V. ; Recalde, M. ; Rodríguez, C.; Martínez-González, J.; Andrés, V.; Martín-Sanz, P. ; Boscá, L. "Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis † ." . Cells. 9(9): . (2020). (PMID: 32927803).
González-Ramos, S. ; Paz-García, M. ; Fernández-García, V. ; Portune, K.J.; Acosta-Medina, E.F.; Sanz, Y.; Castrillo, A. ; Martín-Sanz, P. ; Obregon, M.J. ; Boscá, L. "NOD1 deficiency promotes an imbalance of thyroid hormones and microbiota homeostasis in mice fed high fat diet." . Sci Rep. 10(1): 12317. (2020). (PMID: 32704052).
Haider, N.; Boscá, L. ; Zandbergen, H.R.; Kovacic, J.C.; Narula, N.; González-Ramos, S. ; Fernandez-Velasco, M.; Agrawal, S.; Paz-García, M. ; Gupta, S.; DeLeon-Pennell, K.; Fuster, V.; Ibañez, B.; Narula, J. "Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction." . J. Am. Coll. Cardiol.. 74(25): 3124-3135. (2019). (PMID: 31856969).
González-Ramos, S. ; Paz-García, M. ; Rius, C.; Del Monte-Monge, A.; Rodríguez, C.; Fernández-García, V. ; Andrés, V.; Martínez-González, J.; Lasunción, M.A.; Martín-Sanz, P. ; Soehnlein, O.; Boscá, L. "Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1." . FASEB J.. 33(3): 3912-3921. (2019). (PMID: 30496704).
Mojena, M. ; Povo-Retana, A. ; González-Ramos, S. ; Fernández-García, V. ; Regadera, J.; Zazpe, A.; Artaiz, I.; Martín-Sanz, P. ; Ledo, F.; Boscá, L. "Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells." . Front Oncol. 8(): 328. (2018). (PMID: 30191142).
Mojena, M. ; Pimentel-Santillana, M. ; Povo-Retana, A. ; Fernández-García, V. ; González-Ramos, S. ; Rada, P. ; Tejedor, A.; Rico, D.; Martín-Sanz, P. ; Valverde, A.M. ; Boscá, L. "Protection against gamma-radiation injury by protein tyrosine phosphatase 1B." . Redox Biol. 17(): 213-223. (2018). (PMID: 29705509).
Singh, P.; González-Ramos, S. ; Mojena, M. ; Rosales-Mendoza, C.E.; Emami, H.; Swanson, J.; Morss, A.; Fayad, Z.A.; Rudd, J.H.; Gelfand, J.; Paz-García, M. ; Martín-Sanz, P. ; Boscá, L. ; Tawakol, A. "GM-CSF Enhances Macrophage Glycolytic Activity In Vitro and Improves Detection of Inflammation In Vivo." . J. Nucl. Med.. 57(9): 1428-1435. (2016). (PMID: 27081166).
Boscá, L. ; González-Ramos, S. ; Prieto, P. ; Fernández-Velasco, M. ; Mojena, M. ; Martín-Sanz, P. ; Alemany, S. "Metabolic signatures linked to macrophage polarization: from glucose metabolism to oxidative phosphorylation." . Biochem. Soc. Trans.. 43(4): 740-744. (2015). (PMID: 26551722).
Delgado, C. ; Ruiz-Hurtado, G.; Gómez-Hurtado, N. ; González-Ramos, S. ; Rueda, A.; Benito, G. ; Prieto, P. ; Zaragoza, C.; Delicado, E.G.; Pérez-Sen, R.; Miras-Portugal, M.T.; Núñez, G.; Boscá, L. ; Fernández-Velasco, M. "NOD1, A new player in cardiac function and calcium handling." . Cardiovasc. Res.. (): . (2015). (PMID: 25824149). CONCLUSION Our data provide the first evidence that NOD1 activation induces cardiac dysfunction associated with excitation-contraction coupling-impairment through NF-κB activation, and uncover a new proinflammatory player in the regulation of cardiovascular function.
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Fernández-Velasco, M. ; González-Ramos, S. ; Boscá, L. "Involvement of monocytes/macrophages as key factors in the development and progression of cardiovascular diseases." . Biochem. J.. 458(2): 187-193. (2014). (PMID: 24524191).