INVESTIGACIÓN

 
  • Grupos de Investigación
  • Unidades de Investigación
  • Memoria Cientifíca
  • Publicaciones
espacio

 

PUBLICACIONES

 

 

spacerTrabajos Publicados por Ana Isabel Arroba Espinosa
spacer
  1. Cano-Cano, F.; Alcalde-Estévez, E.; Gómez-Jaramillo, L.; Iturregui, M.; Sánchez-Fernández, E.M.; García Fernández, J.M.; Ortiz Mellet, C.; Campos-Caro, A.; López-Tinoco, C.; Aguilar-Diosdado, M.; Valverde, Á.M.; Arroba, A.I. "Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy.". Front Immunol. 12(): 632132. (2021). (PMID: 33815384).
    spacer

  2. Hernández, C.; Arroba, A.I.; Bogdanov, P.; Ramos, H.; Simó-Servat, O.; Simó, R.; Valverde, A.M. "Effect of Topical Administration of Somatostatin on Retinal Inflammation and Neurodegeneration in an Experimental Model of Diabetes.". J Clin Med. 9(8): . (2020). (PMID: 32784955).
    spacer

  3. Villar-Lorenzo, A.; Rada, P.; Rey, E.; Marañón, P.; Arroba, A.I.; Santamaría, B.; Sáiz, J.; Rupérez, F.J.; Barbas, C.; García-Monzón, C.; Valverde, Á.M.; González-Rodríguez, Á. "Insulin receptor substrate 2 (IRS2) deficiency delays liver fibrosis associated with cholestatic injury.". Dis Model Mech. 12(7): . (2019). (PMID: 31262748).
    spacer

  4. Arroba, A.I.; Campos-Caro, A.; Aguilar-Diosdado, M.; Valverde, Á.M. "IGF-1, Inflammation and Retinal Degeneration: A Close Network.". Front Aging Neurosci. 10(): 203. (2018). (PMID: 30026694).
    spacer

  5. Beltramo, E.; Arroba, A.I.; Mazzeo, A.; Valverde, A.M.; Porta, M. "Imbalance between pro-apoptotic and pro-survival factors in human retinal pericytes in diabetic-like conditions.". Acta Ophthalmol. 96(1): e19-e26. (2018). (PMID: 28127871).
    spacer

  6. Alcalde-Estévez, E.; Arroba, A.I.; Sánchez-Fernández, E.M.; Mellet, C.O.; García Fernández, J.M.; Masgrau, L.; Valverde, Á.M. "The sp2-iminosugar glycolipid 1-dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin (DSO2-ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explants.". Food Chem. Toxicol.. 111(): 454-466. (2018). (PMID: 29191728).
    spacer

  7. Mazzeo, A.; Arroba, A.I.; Beltramo, E.; Valverde, A.M.; Porta, M. "Somatostatin protects human retinal pericytes from inflammation mediated by microglia.". Exp. Eye Res.. 164(): 46-54. (2017). (PMID: 28734673).
    spacer

  8. Arroba, A.I.; Valverde, Á.M. "Modulation of microglia in the retina: new insights into diabetic retinopathy.". Acta Diabetol. 54(6): 527-533. (2017). (PMID: 28349217).
    spacer

  9. Valdecantos, M.P.; Pardo, V.; Ruiz, L.; Castro-Sánchez, L.; Lanzón, B.; Fernández-Millán, E.; García-Monzón, C.; Arroba, A.I.; González-Rodríguez, Á.; Escrivá, F.; Álvarez, C.; Rupérez, F.J.; Barbas, C.; Konkar, A.; Naylor, J.; Hornigold, D.; Santos, A.D.; Bednarek, M.; Grimsby, J.; Rondinone, C.M.; Valverde, Á.M. "A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice.". Hepatology. 65(3): 950-968. (2017). (PMID: 27880981).
    spacer

  10. Beltramo, E.; Lopatina, T.; Mazzeo, A.; Arroba, A.I.; Valverde, A.M.; Hernández, C.; Simó, R.; Porta, M. "Effects of the neuroprotective drugs somatostatin and brimonidine on retinal cell models of diabetic retinopathy.". Acta Diabetol. 53(6): 957-964. (2016). (PMID: 27552833).
    spacer

  11. Villar-Lorenzo, A.; Ardiles, A.E.; Arroba, A.I.; Hernández-Jiménez, E.; Pardo, V.; López-Collazo, E.; Jiménez, I.A.; Bazzocchi, I.L.; González-Rodríguez, Á.; Valverde, Á.M. "Friedelane-type triterpenoids as selective anti-inflammatory agents by regulation of differential signaling pathways in LPS-stimulated macrophages.". Toxicol. Appl. Pharmacol.. 313(): 57-67. (2016). (PMID: 27751938).
    spacer

  12. Arroba, A.I.; Mazzeo, A.; Cazzoni, D.; Beltramo, E.; Hernández, C.; Porta, M.; Simó, R.; Valverde, Á.M. "Somatostatin protects photoreceptor cells against high glucose-induced apoptosis.". Mol. Vis.. 22(): 1522-1531. (2016). (PMID: 28050125).
    spacer

  13. Arroba, A.I.; Rodríguez-de la Rosa, L.; Murillo-Cuesta, S.; Vaquero-Villanueva, L.; Hurlé, J.M.; Varela-Nieto, I.; Valverde, Á.M. "Autophagy resolves early retinal inflammation in Igf1-deficient mice.". Dis Model Mech. 9(9): 965-974. (2016). (PMID: 27483352).
    spacer

  14. Arroba, A.I.; Alcalde-Estevez, E.; García-Ramírez, M.; Cazzoni, D.; de la Villa, P.; Sánchez-Fernández, E.M.; Mellet, C.O.; García Fernández, J.M.; Hernández, C.; Simó, R.; Valverde, Á.M. "Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice.". Biochim. Biophys. Acta. 1862(9): 1663-1674. (2016). (PMID: 27267343).
    spacer

  15. García-Casarrubios, E.; de Moura, C.; Arroba, A.I.; Pescador, N.; Calderon-Dominguez, M.; Garcia, L.; Herrero, L.; Serra, D.; Cadenas, S.; Reis, F.; Carvalho, E.; Obregon, M.J.; Valverde, Á.M. "Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.". Biochim. Biophys. Acta. 1861(12 Pt A): 1929-1941. (2016). (PMID: 27686967).
    spacer

  16. Hernández, C.; Bogdanov, P.; Corraliza, L.; García-Ramírez, M.; Solà-Adell, C.; Arranz, J.A.; Arroba, A.I.; Valverde, A.M.; Simó, R. "Topical Administration of GLP-1 Receptor Agonists Prevents Retinal Neurodegeneration in Experimental Diabetes.". Diabetes. 65(1): 172-187. (2016). (PMID: 26384381).
    spacer

  17. Arroba, A.I.; Valverde, Á.M. "Inhibition of Protein Tyrosine Phosphatase 1B Improves IGF-I Receptor Signaling and Protects Against Inflammation-Induced Gliosis in the Retina.". Invest. Ophthalmol. Vis. Sci.. 56(13): 8031-8044. (2015). (PMID: 26720454).
    spacer

  18. Arroba, A.I.; Revuelta-Cervantes, J.; Menes, L.; González-Rodríguez, Á.; Pardo, V.; de la Villa, P.; Burks, D.J.; Valverde, Á.M. "Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice.". Invest. Ophthalmol. Vis. Sci.. 54(6): 4215-4225. (2013). (PMID: 23702782).
    spacer

 

 

 

 

 

Instituto de Investigaciones Biomédicas "Alberto Sols"
C/Arturo Duperier 4. 28029 Madrid. (Spain)
Tel +(34) 91 585 4400 // Fax +(34) 91 558 4401
Email:Info