Martinez-deMena, R.; Calvo, R.M.; Garcia, L.; Obregon, M.J. "Effect of glucocorticoids on the activity, expression and proximal promoter of type II deiodinase in rat brown adipocytes.". Mol. Cell. Endocrinol.. 428(): 58-67. (2016). (PMID: 26994513).
Castro, I.; Quisenberry, L.; Calvo, R.M.; Obregon, M.J.; Lado-Abeal, J. "Septic shock non-thyroidal illness syndrome causes hypothyroidism and conditions for reduced sensitivity to thyroid hormone.". J. Mol. Endocrinol.. 50(2): 255-266. (2013). (PMID: 23296981).
Lavado-Autric, R.; Calvo, R.M.; de Mena, R.M.; de Escobar, G.M.; Obregon, M.J. "Deiodinase activities in thyroids and tissues of iodine-deficient female rats.". Endocrinology. 154(1): 529-536. (2013). (PMID: 23142811).
Tinahones, F.J.; Coín-Aragüez, L.; Mayas, M.D.; Garcia-Fuentes, E.; Hurtado-Del-Pozo, C.; Vendrell, J.; Cardona, F.; Calvo, R.M.; Obregon, M.J.; El Bekay, R. "Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels.". BMC Physiol.. 12(): 4. (2012). (PMID: 22471305).
Hurtado del Pozo, C.; Vesperinas-García, G.; Rubio, M.Á.; Corripio-Sánchez, R.; Torres-García, A.J.; Obregon, M.J.; Calvo, R.M. "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity.". Biochim. Biophys. Acta. 1811(12): 1194-1200. (2011). (PMID: 21840420).
Calvo, R.M.; Obregon, M.J. "Presence and regulation of D1 and D2 deiodinases in rat white adipose tissue.". Metab. Clin. Exp.. 60(9): 1207-1210. (2011). (PMID: 21397282).
del Pozo, C.H.; Calvo, R.M.; Vesperinas-García, G.; Gómez-Ambrosi, J.; Frühbeck, G.; Rubio, M.A.; Obregon, M.J. "Expression profile in omental and subcutaneous adipose tissue from lean and obese subjects. Repression of lipolytic and lipogenic genes.". Obes Surg. 21(5): 633-643. (2011). (PMID: 20686928).
Hurtado del Pozo, C.; Calvo, R.M.; Vesperinas-García, G.; Gómez-Ambrosi, J.; Frühbeck, G.; Corripio-Sánchez, R.; Rubio, M.A.; Obregon, M.J. "IPO8 and FBXL10: new reference genes for gene expression studies in human adipose tissue.". Obesity (Silver Spring). 18(5): 897-903. (2010). (PMID: 19876011).
Lado-Abeal, J.; Calvo, R.M.; Victoria, B.; Castro, I.; Obregon, M.J.; Araujo-Vilar, D. "Regional decrease of subcutaneous adipose tissue in patients with type 2 familial partial lipodystrophy is associated with changes in thyroid hormone metabolism.". Thyroid. 20(4): 419-424. (2010). (PMID: 20373986).
Calvo, R.M.; Obregon, M.J. "Tri-iodothyronine upregulates adiponutrin mRNA expression in rat and human adipocytes.". Mol. Cell. Endocrinol.. 311(1-2): 39-46. (2009). (PMID: 19619606).
Isorna, E.; Obregon, M.J.; Calvo, R.M.; Vázquez, R.; Pendón, C.; Falcón, J.; Muñoz-Cueto, J.A. "Iodothyronine deiodinases and thyroid hormone receptors regulation during flatfish (Solea senegalensis) metamorphosis.". J. Exp. Zool. B Mol. Dev. Evol.. 312B(3): 231-246. (2009). (PMID: 19306324).
Medina-Gomez, G.; Calvo, R.M.; Obregon, M.J. "Thermogenic effect of triiodothyroacetic acid at low doses in rat adipose tissue without adverse side effects in the thyroid axis.". Am. J. Physiol. Endocrinol. Metab.. 294(4): E688-97. (2008). (PMID: 18285526).
Palos, F.; García-Rendueles, M.E.; Araujo-Vilar, D.; Obregon, M.J.; Calvo, R.M.; Cameselle-Teijeiro, J.; Bravo, S.B.; Perez-Guerra, O.; Loidi, L.; Czarnocka, B.; Alvarez, P.; Refetoff, S.; Dominguez-Gerpe, L.; Alvarez, C.V.; Lado-Abeal, J. "Pendred syndrome in two Galician families: insights into clinical phenotypes through cellular, genetic, and molecular studies.". J. Clin. Endocrinol. Metab.. 93(1): 267-277. (2008). (PMID: 17940114).
Obregon, M.J.; Calvo, R.M.; Del Rey, F.E.; de Escobar, G.M. "Ontogenesis of thyroid function and interactions with maternal function.". Endocr Dev. 10(): 86-98. (2007). (PMID: 17684391).
Medina-Gomez, G.; Calvo, R.M.; Obregón, M.J. "T3 and Triac inhibit leptin secretion and expression in brown and white rat adipocytes.". Biochim. Biophys. Acta. 1682(1-3): 38-47. (2004). (PMID: 15158754).
Khan, I.; Osaka, H.; Stanislaus, S.; Calvo, R.M.; Deerinck, T.; Yaksh, T.L.; Taylor, P. "Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways.". J. Comp. Neurol.. 467(1): 44-59. (2003). (PMID: 14574679).
Medina-Gomez, G.; Hernàndez, A.; Calvo, R.M.; Martin, E.; Obregón, M.J. "Potent thermogenic action of triiodothyroacetic acid in brown adipocytes.". Cell. Mol. Life Sci.. 60(9): 1957-1967. (2003). (PMID: 14523556).
Escobar-Morreale, H.F.; Calvo, R.M.; Villuendas, G.; Sancho, J.; San Millán, J.L. "Association of polymorphisms in the interleukin 6 receptor complex with obesity and hyperandrogenism.". Obes. Res.. 11(8): 987-996. (2003). (PMID: 12917504).
Calvo, R.M.; Jauniaux, E.; Gulbis, B.; Asunción, M.; Gervy, C.; Contempré, B.; Morreale de Escobar, G. "Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development.". J. Clin. Endocrinol. Metab.. 87(4): 1768-1777. (2002). (PMID: 11932315).
Calvo, R.M.; Tellería, D.; Sancho, J.; San Millán, J.L.; Escobar-Morreale, H.F. "Insulin gene variable number of tandem repeats regulatory polymorphism is not associated with hyperandrogenism in Spanish women.". Fertil. Steril.. 77(4): 666-668. (2002). (PMID: 11937112).
Escobar-Morreale, H.F.; Peral, B.; Villuendas, G.; Calvo, R.M.; Sancho, J.; San Millán, J.L. "Common single nucleotide polymorphisms in intron 3 of the calpain-10 gene influence hirsutism.". Fertil. Steril.. 77(3): 581-587. (2002). (PMID: 11872216).
Escobar-Morreale, H.F.; Asunción, M.; Calvo, R.M.; Sancho, J.; San Millán, J.L. "Receiver operating characteristic analysis of the performance of basal serum hormone profiles for the diagnosis of polycystic ovary syndrome in epidemiological studies.". Eur. J. Endocrinol.. 145(5): 619-624. (2001). (PMID: 11720881).
Aláez, C.; Calvo, R.; Obregón, M.J.; Alvarez, C.; Goya, L.; Escrivá, F.; Martín, M.A.; Pascual-Leone, A.M. "Influence of type II 5' deiodinase on TSH content in diabetic rats.". J. Physiol. Biochem.. 57(3): 221-230. (2001). (PMID: 11800284).
Escobar-Morreale, H.F.; Calvo, R.M.; Sancho, J.; San Millán, J.L. "TNF-alpha and hyperandrogenism: a clinical, biochemical, and molecular genetic study.". J. Clin. Endocrinol. Metab.. 86(8): 3761-3767. (2001). (PMID: 11502808).
Calvo, R.M.; Villuendas, G.; Sancho, J.; San Millán, J.L.; Escobar-Morreale, H.F. "Role of the follistatin gene in women with polycystic ovary syndrome.". Fertil. Steril.. 75(5): 1020-1023. (2001). (PMID: 11334920).
San Millán, J.L.; Sancho, J.; Calvo, R.M.; Escobar-Morreale, H.F. "Role of the pentanucleotide (tttta)(n) polymorphism in the promoter of the CYP11a gene in the pathogenesis of hirsutism.". Fertil. Steril.. 75(4): 797-802. (2001). (PMID: 11287037).
Calvo, R.M.; Asunción, M.; Tellería, D.; Sancho, J.; San Millán, J.L.; Escobar-Morreale, H.F. "Screening for mutations in the steroidogenic acute regulatory protein and steroidogenic factor-1 genes, and in CYP11A and dosage-sensitive sex reversal-adrenal hypoplasia gene on the X chromosome, gene-1 (DAX-1), in hyperandrogenic hirsute women.". J. Clin. Endocrinol. Metab.. 86(4): 1746-1749. (2001). (PMID: 11297612).
Asunción, M.; Calvo, R.M.; San Millán, J.L.; Sancho, J.; Avila, S.; Escobar-Morreale, H.F. "A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain.". J. Clin. Endocrinol. Metab.. 85(7): 2434-2438. (2000). (PMID: 10902790).
Calvo, R.M.; Asunción, M.; Sancho, J.; San Millán, J.L.; Escobar-Morreale, H.F. "The role of the CAG repeat polymorphism in the androgen receptor gene and of skewed X-chromosome inactivation, in the pathogenesis of hirsutism.". J. Clin. Endocrinol. Metab.. 85(4): 1735-1740. (2000). (PMID: 10770223).
Calvo, R.M.; Forcen, R.; Obregon, M.J.; Escobar del Rey, F.; Morreale de Escobar, G.; Regadera, J. "Immunohistochemical and morphometric studies of the fetal pancreas in diabetic pregnant rats. Effects of insulin administration.". Anat. Rec.. 251(2): 173-180. (1998). (PMID: 9624446).
Calvo, R.; Morreale de Escobar, G.; Escobar del Rey, F.; Obregón, M.J. "Maternal nonthyroidal illness and fetal thyroid hormone status, as studied in the streptozotocin-induced diabetes mellitus rat model.". Endocrinology. 138(3): 1159-1169. (1997). (PMID: 9048623).
Calvo, R.; Morreale de Escobar, G.; Escobar del Rey, F.; Obregón, M.J. "Maternal diabetes mellitus, a rat model for nonthyroidal illness: correction of hypothyroxinemia with thyroxine treatment does not improve fetal thyroid hormone status.". Thyroid. 7(1): 79-87. (1997). (PMID: 9086576).
Obregón, M.J.; Calvo, R.; Hernández, A.; Escobar del Rey, F.; Morreale de Escobar, G. "Regulation of uncoupling protein messenger ribonucleic acid and 5'-deiodinase activity by thyroid hormones in fetal brown adipose tissue.". Endocrinology. 137(11): 4721-4729. (1996). (PMID: 8895339).
Solé, E.; Calvo, R.; Obregón, M.J.; Meseguer, A. "Effects of thyroid hormone on the androgenic expression of KAP gene in mouse kidney.". Mol. Cell. Endocrinol.. 119(2): 147-159. (1996). (PMID: 8807634).
Chapa, F.; Künnecke, B.; Calvo, R.; Escobar del Rey, F.; Morreale de Escobar, G.; Cerdán, S. "Adult-onset hypothyroidism and the cerebral metabolism of (1,2-13C2) acetate as detected by 13C nuclear magnetic resonance.". Endocrinology. 136(1): 296-305. (1995). (PMID: 7828544).
Joffe, R.T.; Nobrega, J.N.; Kish, S.J.; Calvo, R.; Dixon, L.M.; Wilson, J.M.; Morreale de Escobar, G. "Regional thyroid hormone levels in rat brain.". Psychoneuroendocrinology. 19(8): 773-777. (1994). (PMID: 7991764).
Pascual-Leone, A.M.; Aláez, C.; Calvo, R.; Martín, M.A.; Obregón, M.J. "Effects of thyroid hormone deiodination on regulation of thyroid axis in undernourished rats.". Am. J. Physiol.. 267(6 Pt 1): E983-9. (1994). (PMID: 7810644).
Solé, E.; Calvo, R.; Obregón, M.J.; Meseguer, A. "Thyroid hormone controls the cell-specific expression of the kidney androgen-regulated protein gene in S3 mouse kidney cells.". Endocrinology. 135(5): 2120-2129. (1994). (PMID: 7956935).
Ruiz-Marcos, A.; Cartagena-Abella, P.; Martinez-Galan, J.R.; Calvo, R.; Morreale de Escobar, G.; Escobar del Rey, F. "Thyroxine treatment and the recovery of pyramidal cells of the cerebral cortex from changes induced by juvenile-onset hypothyroidism.". J. Neurobiol.. 25(7): 808-818. (1994). (PMID: 8089658).
Contempré, B.; Jauniaux, E.; Calvo, R.; Jurkovic, D.; Campbell, S.; de Escobar, G.M. "Detection of thyroid hormones in human embryonic cavities during the first trimester of pregnancy.". J. Clin. Endocrinol. Metab.. 77(6): 1719-1722. (1993). (PMID: 8263162).
Joffe, R.; Nobrega, J.; Kish, S.; Calvo, R.; Dixon, L.; Wilson, J. "Desipramine reduces plasma but not brain thyroxine levels.". Biol. Psychiatry. 33(4): 293-294. (1993). (PMID: 8471684).
Morreale de Escobar, G.; Obregón, M.J.; Calvo, R.; Escobar del Rey, F. "Effects of iodine deficiency on thyroid hormone metabolism and the brain in fetal rats: the role of the maternal transfer of thyroxin.". Am. J. Clin. Nutr.. 57(2 Suppl): 280S-285S. (1993). (PMID: 8427205).
Prati, M.; Calvo, R.; Morreale, G.; Morreale de Escobar, G. "L-thyroxine and 3,5,3'-triiodothyronine concentrations in the chicken egg and in the embryo before and after the onset of thyroid function.". Endocrinology. 130(5): 2651-2659. (1992). (PMID: 1572286).
Morreale de Escobar, G.; Obregón, M.J.; Calvo, R.; Escobar del Rey, F. "Maternal thyroid hormones during pregnancy: effects on the fetus in congenital hypothyroidism and in iodine deficiency.". Adv. Exp. Med. Biol.. 299(): 133-156. (1991). (PMID: 1810132).
Obregón, M.J.; Ruiz de Oña, C.; Calvo, R.; Escobar del Rey, F.; Morreale de Escobar, G. "Outer ring iodothyronine deiodinases and thyroid hormone economy: responses to iodine deficiency in the rat fetus and neonate.". Endocrinology. 129(5): 2663-2673. (1991). (PMID: 1935795).
Calvo, R.; Obregón, M.J.; Ruiz de Oña, C.; Escobar del Rey, F.; Morreale de Escobar, G. "Congenital hypothyroidism, as studied in rats. Crucial role of maternal thyroxine but not of 3,5,3'-triiodothyronine in the protection of the fetal brain.". J. Clin. Invest.. 86(3): 889-899. (1990). (PMID: 2394838).
Calvo, R.; Obregon, M.J.; Ruiz de Oña, C.; Ferreiro, B.; Escobar Del Rey, E.; Morreale de Escobar, G. "Thyroid hormone economy in pregnant rats near term: a "physiological" animal model of nonthyroidal illness?". Endocrinology. 127(1): 10-16. (1990). (PMID: 2113860).
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