INVESTIGACIÓN

 
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PUBLICACIONES

 

 

spacerTrabajos Publicados por Miguel Quintanilla Ávila
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  1. Mendoza, G.; González-Pastor, R.; Sánchez, J.M.; Arce-Cerezo, A.; Quintanilla, M.; Moreno-Bueno, G.; Pujol, A.; Belmar-López, C.; de Martino, A.; Riu, E.; Rodriguez, T.A.; Martin-Duque, P. "The E1a Adenoviral Gene Upregulates the Yamanaka Factors to Induce Partial Cellular Reprogramming.". Cells. 12(9): . (2023). (PMID: 37174738).
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  2. Belmar-López, C.; Vassaux, G.; Medel-Martinez, A.; Burnet, J.; Quintanilla, M.; Ramón Y Cajal, S.; Hernandez-Losa, J.; De la Vieja, A.; Martin-Duque, P. "Mesenchymal Stem Cells Delivery in Individuals with Different Pathologies: Multimodal Tracking, Safety and Future Applications.". Int J Mol Sci. 23(3): . (2022). (PMID: 35163605).
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  3. Gonzalez-Pastor, R.; Hernandez, Y.; Gimeno, M.; de Martino, A.; Man, Y.K.S.; Hallden, G.; Quintanilla, M.; de la Fuente, J.M.; Martin-Duque, P. "Coating an adenovirus with functionalized gold nanoparticles favors uptake, intracellular trafficking and anti-cancer therapeutic efficacy.". Acta Biomater. (): . (2021). (PMID: 34325075).
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  4. Montero-Montero, L.; Renart, J.; Ramírez, A.; Ramos, C.; Shamhood, M.; Jarcovsky, R.; Quintanilla, M.; Martín-Villar, E. "Interplay between Podoplanin, CD44s and CD44v in Squamous Carcinoma Cells.". Cells. 9(10): . (2020). (PMID: 33003440).
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  5. Cruz-Bermúdez, A.; Vallejo, C.G.; Vicente-Blanco, R.J.; Gallardo, M.E.; Fernández-Moreno, M.Á.; Quintanilla, M.; Garesse, R. "Correction: Enhanced tumorigenicity by mitochondrial DNA mild mutations.". Oncotarget. 11(11): 1006. (2020). (PMID: 32215189).
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  6. Luengo-Gil, G.; García-Andreo, A.B.; Ortega-Sabater, C.; Bohdan, N.; Espín, S.; Peñas-Martínez, J.; Martínez-Planes, E.; García-Hernández, Á.; Vicente, V.; Quintanilla, M.; Martínez-Martínez, I. "Antithrombin is incorporated into exosomes produced by antithrombin non-expressing cells.". Biochimie. 165(): 245-249. (2019). (PMID: 31445073).
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  7. Gallardo-Vara, E.; Ruiz-Llorente, L.; Casado-Vela, J.; Ruiz-Rodríguez, M.J.; López-Andrés, N.; Pattnaik, A.K.; Quintanilla, M.; Bernabeu, C. "Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners.". Cells. 8(9): . (2019). (PMID: 31540324).
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  8. Moncho-Amor, V.; Pintado-Berninches, L.; Ibañez de Cáceres, I.; Martín-Villar, E.; Quintanilla, M.; Chakravarty, P.; Cortes-Sempere, M.; Fernández-Varas, B.; Rodriguez-Antolín, C.; de Castro, J.; Sastre, L.; Perona, R. "Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer.". Int J Mol Sci. 20(8): . (2019). (PMID: 31027181).
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  9. Quintanilla, M.; Montero-Montero, L.; Renart, J.; Martín-Villar, E. "Podoplanin in Inflammation and Cancer.". Int J Mol Sci. 20(3): . (2019). (PMID: 30736372).
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  10. Calvo-Sánchez, M.I.; Fernández-Martos, S.; Carrasco, E.; Moreno-Bueno, G.; Bernabéu, C.; Quintanilla, M.; Espada, J. "A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle.". J Mol Cell Biol. 11(1): 39-52. (2019). (PMID: 30239775).
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  11. da Silva, I.L.; Montero-Montero, L.; Ferreira, E.; Quintanilla, M. "New Insights Into the Role of Qa-2 and HLA-G Non-classical MHC-I Complexes in Malignancy.". Front Immunol. 9(): 2894. (2018). (PMID: 30574154).
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  12. Bresson, L.; Faraldo, M.M.; Di-Cicco, A.; Quintanilla, M.; Glukhova, M.A.; Deugnier, M.A. "Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.". Development. 145(4): . (2018). (PMID: 29361573).
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  13. da Silva, I.L.; Veloso, E.S.; Gonçalves, I.N.N.; Braga, A.D.; Lopes, M.T.P.; Cassali, G.D.; Quintanilla, M.; Simões, R.T.; Ferreira, E. "Qa-2 expression levels is related with tumor-infiltrating lymphocytes profile during solid Ehrlich tumor development.". Biomed. Pharmacother.. 92(): 750-756. (2017). (PMID: 28591688).
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  14. da Silva, I.L.; Montero-Montero, L.; Martín-Villar, E.; Martin-Pérez, J.; Sainz, B.; Renart, J.; Toscano Simões, R.; Soares Veloso, É.; Salviano Teixeira, C.; de Oliveira, M.C.; Ferreira, E.; Quintanilla, M. "Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells.". Sci Rep. 7(1): 6276. (2017). (PMID: 28740236).
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  15. Andradas, C.; Blasco-Benito, S.; Castillo-Lluva, S.; Dillenburg-Pilla, P.; Diez-Alarcia, R.; Juanes-García, A.; García-Taboada, E.; Hernando-Llorente, R.; Soriano, J.; Hamann, S.; Wenners, A.; Alkatout, I.; Klapper, W.; Rocken, C.; Bauer, M.; Arnold, N.; Quintanilla, M.; Megías, D.; Vicente-Manzanares, M.; Urigüen, L.; Gutkind, J.S.; Guzmán, M.; Pérez-Gómez, E.; Sánchez, C. "Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer.". Oncotarget. 7(30): 47565-47575. (2016). (PMID: 27340777).
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  16. Kucia-Tran, J.A.; Tulkki, V.; Smith, S.; Scarpini, C.G.; Hughes, K.; Araujo, A.M.; Yan, K.Y.; Botthof, J.; Pérez-Gómez, E.; Quintanilla, M.; Cuschieri, K.; Caffarel, M.M.; Coleman, N. "Overexpression of the oncostatin-M receptor in cervical squamous cell carcinoma is associated with epithelial-mesenchymal transition and poor overall survival.". Br. J. Cancer. 115(2): 212-222. (2016). (PMID: 27351213).
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  17. Luengo-Gil, G.; Calvo, M.I.; Martín-Villar, E.; Águila, S.; Bohdan, N.; Antón, A.I.; Espín, S.; Ayala de la Peña, F.; Vicente, V.; Corral, J.; Quintanilla, M.; Martínez-Martínez, I. "Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase.". Sci Rep. 6(): 27544. (2016). (PMID: 27270881).
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  18. Carrasco-Ramírez, P.; Greening, D.W.; Andrés, G.; Gopal, S.K.; Martín-Villar, E.; Renart, J.; Simpson, R.J.; Quintanilla, M. "Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation.". Oncotarget. 7(13): 16070-16089. (2016). (PMID: 26893367).
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  19. Martín-Villar, E.; Borda-d'Agua, B.; Carrasco-Ramirez, P.; Renart, J.; Parsons, M.; Quintanilla, M.; Jones, G.E. "Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability.". Oncogene. 34(34): 4531-4544. (2015). (PMID: 25486435).
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  20. Pérez-Gómez, E.; Andradas, C.; Blasco-Benito, S.; Caffarel, M.M.; García-Taboada, E.; Villa-Morales, M.; Moreno, E.; Hamann, S.; Martín-Villar, E.; Flores, J.M.; Wenners, A.; Alkatout, I.; Klapper, W.; Röcken, C.; Bronsert, P.; Stickeler, E.; Staebler, A.; Bauer, M.; Arnold, N.; Soriano, J.; Pérez-Martínez, M.; Megías, D.; Moreno-Bueno, G.; Ortega-Gutiérrez, S.; Artola, M.; Vázquez-Villa, H.; Quintanilla, M.; Fernández-Piqueras, J.; Canela, E.I.; McCormick, P.J.; Guzmán, M.; Sánchez, C. "Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer.". J. Natl. Cancer Inst.. 107(6): djv077. (2015). (PMID: 25855725).
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  21. Cruz-Bermúdez, A.; Vallejo, C.G.; Vicente-Blanco, R.J.; Gallardo, M.E.; Fernández-Moreno, M.Á.; Quintanilla, M.; Garesse, R. "Enhanced tumorigenicity by mitochondrial DNA mild mutations.". Oncotarget. 6(15): 13628-13643. (2015). (PMID: 25909222).
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  22. Salazar, M.; Lorente, M.; García-Taboada, E.; Gómez, E.P.; Dávila, D.; Zúñiga-García, P.; Flores, J.M.; Rodríguez, A.; Hegedus, Z.; Mosén-Ansorena, D.; Aransay, A.M.; Hernández-Tiedra, S.; López-Valero, I.; Quintanilla, M.; Sánchez, C.; Iovanna, J.L.; Dusetti, N.; Guzmán, M.; Francis, S.E.; Carracedo, A.; Kiss-Toth, E.; Velasco, G. "TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling.". Mol Cell Oncol. 2(3): e980134. (2015). (PMID: 27308456).
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  23. Renart, J.; Carrasco-Ramírez, P.; Fernández-Muñoz, B.; Martín-Villar, E.; Montero, L.; Yurrita, M.M.; Quintanilla, M. "New insights into the role of podoplanin in epithelial-mesenchymal transition.". Int Rev Cell Mol Biol. 317(): 185-239. (2015). (PMID: 26008786).
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  24. del Castillo, G.; Sánchez-Blanco, E.; Martín-Villar, E.; Valbuena-Diez, A.C.; Langa, C.; Pérez-Gómez, E.; Renart, J.; Bernabéu, C.; Quintanilla, M. "Soluble endoglin antagonizes Met signaling in spindle carcinoma cells.". Carcinogenesis. 36(2): 212-222. (2015). (PMID: 25503931).
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  25. Salazar, M.; Lorente, M.; García-Taboada, E.; Pérez Gómez, E.; Dávila, D.; Zúñiga-García, P.; María Flores, J.; Rodríguez, A.; Hegedus, Z.; Mosén-Ansorena, D.; Aransay, A.M.; Hernández-Tiedra, S.; López-Valero, I.; Quintanilla, M.; Sánchez, C.; Iovanna, J.L.; Dusetti, N.; Guzmán, M.; Francis, S.E.; Carracedo, A.; Kiss-Toth, E.; Velasco, G. "Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation.". Cell Death Differ.. 22(1): 131-144. (2015). (PMID: 25168244).
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  26. Tobar, N.; Avalos, M.C.; Méndez, N.; Smith, P.C.; Bernabeu, C.; Quintanilla, M.; Martínez, J. "Soluble MMP-14 produced by bone marrow-derived stromal cells sheds epithelial endoglin modulating the migratory properties of human breast cancer cells.". Carcinogenesis. 35(8): 1770-1779. (2014). (PMID: 24618373).
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  27. Larcher, F.; Espada, J.; Díaz-Ley, B.; Jaén, P.; Juarranz, A.; Quintanilla, M. "New experimental models of skin homeostasis and diseases.". Actas Dermosifiliogr. 106(1): 17-28. (2014). (PMID: 24878038).
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  28. Pérez-Gómez, E.; Jerkic, M.; Prieto, M.; del Castillo, G.; Martín-Villar, E.; Letarte, M.; Bernabeu, C.; Pérez-Barriocanal, F.; Quintanilla, M.; López-Novoa, J.M. "Impaired wound repair in adult endoglin heterozygous mice associated with lower NO bioavailability.". J. Invest. Dermatol.. 134(1): 247-255. (2014). (PMID: 23765132).
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  29. Yurrita, M.M.; Fernández-Muñoz, B.; Del Castillo, G.; Martín-Villar, E.; Renart, J.; Quintanilla, M. "Podoplanin is a substrate of presenilin-1/γ-secretase.". Int. J. Biochem. Cell Biol.. 46(): 68-75. (2014). (PMID: 24275092).
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  30. Vallejo, C.G.; Cruz-Bermúdez, A.; Clemente, P.; Hernández-Sierra, R.; Garesse, R.; Quintanilla, M. "Evaluation of mitochondrial function and metabolic reprogramming during tumor progression in a cell model of skin carcinogenesis.". Biochimie. 95(6): 1171-1176. (2013). (PMID: 23353111).
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  31. Mera-Menéndez, F.; Hinojar-Gutiérrez, A.; Guijarro Rojas, M.; de Gregorio, J.G.; Mera-Menéndez, E.; Sánchez, J.J.; Quintanilla, M.; Cerezo, L.; Gamallo, C. "Polymorphisms in HIF-1alpha affect presence of lymph node metastasis and can influence tumor size in squamous-cell carcinoma of the glottic larynx.". Clin Transl Oncol. 15(5): 358-363. (2013). (PMID: 22914908).
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  32. Pérez-Gómez, E.; Andradas, C.; Flores, J.M.; Quintanilla, M.; Paramio, J.M.; Guzmán, M.; Sánchez, C. "The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas.". Oncogene. 32(20): 2534-2542. (2013). (PMID: 22751111).
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  33. Belmar-Lopez, C.; Mendoza, G.; Oberg, D.; Burnet, J.; Simon, C.; Cervello, I.; Iglesias, M.; Ramirez, J.C.; Lopez-Larrubia, P.; Quintanilla, M.; Martin-Duque, P. "Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivo effects on migration capacity and tumor growth.". BMC Med. 11(): 139. (2013). (PMID: 23710709).
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  34. Santibañez, J.F.; Quintanilla, M.; Bernabeu, C. "TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.". Clin. Sci.. 121(6): 233-251. (2011). (PMID: 21615335).
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  35. Fernández-Muñoz, B.; Yurrita, M.M.; Martín-Villar, E.; Carrasco-Ramírez, P.; Megías, D.; Renart, J.; Quintanilla, M. "The transmembrane domain of podoplanin is required for its association with lipid rafts and the induction of epithelial-mesenchymal transition.". Int. J. Biochem. Cell Biol.. 43(6): 886-896. (2011). (PMID: 21376833).
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  36. Latorre-Romero, C.; Marin-Yaseli, M.R.; Belmar-Lopez, C.; del Moral, R.; Marijuan, P.C.; Quintanilla, M.; Martin-Duque, P. "Using living cells to transport therapeutic genes for cancer treatment.". Clin Transl Oncol. 13(1): 10-17. (2011). (PMID: 21239350).
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  37. Martín-Villar, E.; Fernández-Muñoz, B.; Parsons, M.; Yurrita, M.M.; Megías, D.; Pérez-Gómez, E.; Jones, G.E.; Quintanilla, M. "Podoplanin associates with CD44 to promote directional cell migration.". Mol. Biol. Cell. 21(24): 4387-4399. (2010). (PMID: 20962267).
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  38. Pérez-Gómez, E.; Del Castillo, G.; Juan Francisco, S.; López-Novoa, J.M.; Bernabéu, C.; Quintanilla, M. "The role of the TGF-β coreceptor endoglin in cancer.". ScientificWorldJournal. 10(): 2367-2384. (2010). (PMID: 21170488).
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  39. Santibanez, J.F.; Pérez-Gómez, E.; Fernandez-L, A.; Garrido-Martin, E.M.; Carnero, A.; Malumbres, M.; Vary, C.P.; Quintanilla, M.; Bernabéu, C. "The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras.". Carcinogenesis. 31(12): 2145-2154. (2010). (PMID: 20884686).
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  40. Santibáñez, J.F.; Kocić, J.; Fabra, A.; Cano, A.; Quintanilla, M. "Rac1 modulates TGF-beta1-mediated epithelial cell plasticity and MMP9 production in transformed keratinocytes.". FEBS Lett.. 584(11): 2305-2310. (2010). (PMID: 20353788).
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  41. Hinojar-Gutiérrez, A.; Fernández-Contreras, M.E.; Alvarez-Carrillo, S.; Quintanilla, M.; Gamallo, C. "Role of intratumoral lymphatic vessels in the lymph node dissemination of laryngopharyngeal squamous cell carcinoma.". Head Neck. 32(6): 757-762. (2010). (PMID: 19862828).
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  42. Peerlinck, I.; Merron, A.; Baril, P.; Conchon, S.; Martin-Duque, P.; Hindorf, C.; Burnet, J.; Quintanilla, M.; Hingorani, M.; Iggo, R.; Lemoine, N.R.; Harrington, K.; Vassaux, G. "Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.". Clin. Cancer Res.. 15(21): 6595-6601. (2009). (PMID: 19861465).
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  43. Bernabeu, C.; Lopez-Novoa, J.M.; Quintanilla, M. "The emerging role of TGF-beta superfamily coreceptors in cancer.". Biochim. Biophys. Acta. 1792(10): 954-973. (2009). (PMID: 19607914).
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  44. Martín-Villar, E.; Yurrita, M.M.; Fernández-Muñoz, B.; Quintanilla, M.; Renart, J. "Regulation of podoplanin/PA2.26 antigen expression in tumour cells. Involvement of calpain-mediated proteolysis.". Int. J. Biochem. Cell Biol.. 41(6): 1421-1429. (2009). (PMID: 19146981).
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  45. Blanco, F.J.; Grande, M.T.; Langa, C.; Oujo, B.; Velasco, S.; Rodriguez-Barbero, A.; Perez-Gomez, E.; Quintanilla, M.; López-Novoa, J.M.; Bernabeu, C. "S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology.". Circ. Res.. 103(12): 1383-1392. (2008). (PMID: 18974388).
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  46. Müller, D.; Trunk, G.; Sichelstiel, A.; Zettlitz, K.A.; Quintanilla, M.; Kontermann, R.E. "Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice.". J. Immunol. Methods. 339(1): 90-98. (2008). (PMID: 18790696).
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  47. Montiel-Equihua, C.A.; Martín-Duque, P.; de la Vieja, A.; Quintanilla, M.; Burnet, J.; Vassaux, G.; Lemoine, N.R. "Targeting sodium/iodide symporter gene expression for estrogen-regulated imaging and therapy in breast cancer.". Cancer Gene Ther.. 15(7): 465-473. (2008). (PMID: 18421306).
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  48. Peinado, H.; Moreno-Bueno, G.; Hardisson, D.; Pérez-Gómez, E.; Santos, V.; Mendiola, M.; de Diego, J.I.; Nistal, M.; Quintanilla, M.; Portillo, F.; Cano, A. "Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.". Cancer Res.. 68(12): 4541-4550. (2008). (PMID: 18559498).
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  49. Romero, D.; Iglesias, M.; Vary, C.P.; Quintanilla, M. "Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells.". Carcinogenesis. 29(5): 1070-1076. (2008). (PMID: 18310088).
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  50. Lomas, J.; Martin-Duque, P.; Pons, M.; Quintanilla, M. "The genetics of malignant melanoma.". Front. Biosci.. 13(): 5071-5093. (2008). (PMID: 18508571).
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  51. Pons, M.; Mancheño-Corvo, P.; Martín-Duque, P.; Quintanilla, M. "Molecular biology of malignant melanoma.". Adv. Exp. Med. Biol.. 624(): 252-264. (2008). (PMID: 18348462).
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  52. Belmar-Lopez, C.; Mancheno-Corvo, P.; Saornil, M.A.; Baril, P.; Vassaux, G.; Quintanilla, M.; Martin-Duque, P. "Uveal vs. cutaneous melanoma. Origins and causes of the differences.". Clin Transl Oncol. 10(3): 137-142. (2008). (PMID: 18321815).
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  53. Merron, A.; Peerlinck, I.; Martin-Duque, P.; Burnet, J.; Quintanilla, M.; Mather, S.; Hingorani, M.; Harrington, K.; Iggo, R.; Vassaux, G. "SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene.". Gene Ther.. 14(24): 1731-1738. (2007). (PMID: 17960161).
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  54. Pérez-Gómez, E.; Villa-Morales, M.; Santos, J.; Fernández-Piqueras, J.; Gamallo, C.; Dotor, J.; Bernabéu, C.; Quintanilla, M. "A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis.". Cancer Res.. 67(21): 10268-10277. (2007). (PMID: 17974968).
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  55. Villa-Morales, M.; Santos, J.; Pérez-Gómez, E.; Quintanilla, M.; Fernández-Piqueras, J. "A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas.". Cancer Res.. 67(11): 5107-5116. (2007). (PMID: 17545588).
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  56. Hinojar-Gutiérrez, A.; Fernández-Contreras, M.E.; González-González, R.; Fernández-Luque, M.J.; Hinojar-Arzadún, A.; Quintanilla, M.; Gamallo, C. "Intratumoral lymphatic vessels and VEGF-C expression are predictive factors of lymph node relapse in T1-T4 N0 laryngopharyngeal squamous cell carcinoma.". Ann. Surg. Oncol.. 14(1): 248-257. (2007). (PMID: 17066224).
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  57. Martín-Villar, E.; Megías, D.; Castel, S.; Yurrita, M.M.; Vilaró, S.; Quintanilla, M. "Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition.". J. Cell. Sci.. 119(Pt 21): 4541-4553. (2006). (PMID: 17046996).
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  58. Pons, M.; Quintanilla, M. "Molecular biology of malignant melanoma and other cutaneous tumors.". Clin Transl Oncol. 8(7): 466-474. (2006). (PMID: 16870533).
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  59. Martín-Duque, P.; Quintanilla, M.; McNeish, I.; Lopes, R.; Romero, J.; Romero, D.; Lemoine, N.R.; Ramón y Cajal, S.; Vassaux, G. "Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo.". Int. J. Mol. Med.. 17(5): 841-847. (2006). (PMID: 16596269).
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  60. Pons, M.; Cigudosa, J.C.; Rodríguez-Perales, S.; Bella, J.L.; González, C.; Gamallo, C.; Quintanilla, M. "Chromosomal instability and phenotypic plasticity during the squamous-spindle carcinoma transition: association of a specific T(14;15) with malignant progression.". Oncogene. 24(51): 7608-7618. (2005). (PMID: 16007119).
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  61. Pérez-Gómez, E.; Eleno, N.; López-Novoa, J.M.; Ramirez, J.R.; Velasco, B.; Letarte, M.; Bernabéu, C.; Quintanilla, M. "Characterization of murine S-endoglin isoform and its effects on tumor development.". Oncogene. 24(27): 4450-4461. (2005). (PMID: 15806144).
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  62. Martín-Villar, E.; Scholl, F.G.; Gamallo, C.; Yurrita, M.M.; Muñoz-Guerra, M.; Cruces, J.; Quintanilla, M. "Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas.". Int. J. Cancer. 113(6): 899-910. (2005). (PMID: 15515019).
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  63. Muñoz-Guerra, M.F.; Marazuela, E.G.; Martín-Villar, E.; Quintanilla, M.; Gamallo, C. "Prognostic significance of intratumoral lymphangiogenesis in squamous cell carcinoma of the oral cavity.". Cancer. 100(3): 553-560. (2004). (PMID: 14745872).
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  64. Quintanilla, M.; Ramirez, J.R.; Pérez-Gómez, E.; Romero, D.; Velasco, B.; Letarte, M.; López-Novoa, J.M.; Bernabéu, C. "Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis.". Oncogene. 22(38): 5976-5985. (2003). (PMID: 12955076).
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  65. Peinado, H.; Quintanilla, M.; Cano, A. "Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.". J. Biol. Chem.. 278(23): 21113-21123. (2003). (PMID: 12665527).
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  66. Santibáñez, J.F.; Guerrero, J.; Quintanilla, M.; Fabra, A.; Martínez, J. "Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.". Biochem. Biophys. Res. Commun.. 296(2): 267-273. (2002). (PMID: 12163012).
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  67. Santibáñez, J.F.; Quintanilla, M.; Martínez, J. "TGF-beta(1) and Smad4 overexpression induce a less invasive phenotype in highly invasive spindle carcinoma cells.". FEBS Lett.. 520(1-3): 171-176. (2002). (PMID: 12044892).
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  68. Pálmer, H.G.; González-Sancho, J.M.; Espada, J.; Berciano, M.T.; Puig, I.; Baulida, J.; Quintanilla, M.; Cano, A.; de Herreros, A.G.; Lafarga, M.; Muñoz, A. "Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.". J. Cell Biol.. 154(2): 369-387. (2001). (PMID: 11470825).
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  69. Scholl, F.G.; Gamallo, C.; Quintanilla, M. "Ectopic expression of PA2.26 antigen in epidermal keratinocytes leads to destabilization of adherens junctions and malignant progression.". Lab. Invest.. 80(11): 1749-1759. (2000). (PMID: 11092535).
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  70. Santibáñez, J.F.; Quintanilla, M.; Martínez, J. "Genistein and curcumin block TGF-beta 1-induced u-PA expression and migratory and invasive phenotype in mouse epidermal keratinocytes.". Nutr Cancer. 37(1): 49-54. (2000). (PMID: 10965519).
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  71. Iglesias, M.; Frontelo, P.; Gamallo, C.; Quintanilla, M. "Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas.". Oncogene. 19(36): 4134-4145. (2000). (PMID: 10962574).
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  72. Santibáñez, J.F.; Iglesias, M.; Frontelo, P.; Martínez, J.; Quintanilla, M. "Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-beta(1) in transformed keratinocytes.". Biochem. Biophys. Res. Commun.. 273(2): 521-527. (2000). (PMID: 10873638).
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  73. Duque, P.M.; Alonso, C.; Sánchez-Prieto, R.; Lleonart, M.; Martínez, C.; de Buitrago, G.G.; Cano, A.; Quintanilla, M.; Ramon y Cajal, S. "Adenovirus lacking the 19-kDa and 55-kDa E1B genes exerts a marked cytotoxic effect in human malignant cells.". Cancer Gene Ther.. 6(6): 554-563. (2000). (PMID: 10608352).
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  74. Scholl, F.G.; Gamallo, C.; Vilaró, S.; Quintanilla, M. "Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes.". J. Cell. Sci.. 112 ( Pt 24)(): 4601-4613. (1999). (PMID: 10574709).
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  75. Martin-Duque, P.; Sánchez-Prieto, R.; Romero, J.; Martinez-Lamparero, A.; Cebrian-Sagarriga, S.; Guinea-Viniegra, J.; Dominguez, C.; Lleonart, M.; Cano, A.; Quintanilla, M.; Ramón Y Cajal, S. "In vivo radiosensitizing effect of the adenovirus E1A gene in murine and human malignant tumors.". Int. J. Oncol.. 15(6): 1163-1168. (1999). (PMID: 10568823).
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  76. Santibáñez, J.F.; Frontelo, P.; Iglesias, M.; Martínez, J.; Quintanilla, M. "Urokinase expression and binding activity associated with the transforming growth factor beta1-induced migratory and invasive phenotype of mouse epidermal keratinocytes.". J. Cell. Biochem.. 74(1): 61-73. (1999). (PMID: 10381262).
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  77. Sanchez-Prieto, R.; Quintanilla, M.; Cano, A.; Lleonart, M.; Martin, P.; Ramon y Cajal, S. "In vivo tumor suppressor effect of retrovirus-mediated gene transfer of the adenovirus E1a gene.". Adv. Exp. Med. Biol.. 451(): 79-86. (1998). (PMID: 10026854).
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  78. Frontelo, P.; González-Garrigues, M.; Vilaró, S.; Gamallo, C.; Fabra, A.; Quintanilla, M. "Transforming growth factor beta 1 induces squamous carcinoma cell variants with increased metastatic abilities and a disorganized cytoskeleton.". Exp. Cell Res.. 244(2): 420-432. (1998). (PMID: 9806792).
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  79. Sánchez-Prieto, R.; Quintanilla, M.; Martín, P.; Lleonart, M.; Cano, A.; Dotto, G.P.; Ramón y Cajal, S. "In vivo antitumor effect of retrovirus-mediated gene transfer of the adenovirus E1a gene.". Cancer Gene Ther.. 5(4): 215-224. (1998). (PMID: 9694073).
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  80. Llorens, A.; Rodrigo, I.; López-Barcons, L.; Gonzalez-Garrigues, M.; Lozano, E.; Vinyals, A.; Quintanilla, M.; Cano, A.; Fabra, A. "Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression.". Lab. Invest.. 78(9): 1131-1142. (1998). (PMID: 9759657).
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  81. Duque, P.M.; Alonso, C.; Sanchez-Prieto, R.; Quintanilla, M.; Ramón, S.; Ramon y Cajal, S. "Antitumoral effect of E1B defective adenoviruses in human malignant cells.". Gene Ther.. 5(2): 286-287. (1998). (PMID: 9578851).
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  82. Gandarillas, A.; Scholl, F.G.; Benito, N.; Gamallo, C.; Quintanilla, M. "Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesis.". Mol. Carcinog.. 20(1): 10-18. (1997). (PMID: 9328432).
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  83. Larcher, F.; Robles, A.I.; Duran, H.; Murillas, R.; Quintanilla, M.; Cano, A.; Conti, C.J.; Jorcano, J.L. "Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.". Cancer Res.. 56(23): 5391-5396. (1996). (PMID: 8968091).
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  84. Sánchez-Prieto, R.; Quintanilla, M.; Cano, A.; Leonart, M.L.; Martin, P.; Anaya, A.; Ramón y Cajal, S. "Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene.". Oncogene. 13(5): 1083-1092. (1996). (PMID: 8806698).
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  85. Caulín, C.; López-Barcons, L.; Gonzáles-Garrigues, M.; Navarro, P.; Lozano, E.; Rodrigo, I.; Gamallo, C.; Cano, A.; Fabra, A.; Quintanilla, M. "Suppression of the metastatic phenotype of a mouse skin carcinoma cell line independent of E-cadherin expression and correlated with reduced Ha-ras oncogene products.". Mol. Carcinog.. 15(2): 104-114. (1996). (PMID: 8599577).
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  86. Cano, A.; Gamallo, C.; Kemp, C.J.; Benito, N.; Palacios, J.; Quintanilla, M.; Balmain, A. "Expression pattern of the cell adhesion molecules. E-cadherin, P-cadherin and alpha 6 beta 4 intergrin is altered in pre-malignant skin tumors of p53-deficient mice.". Int. J. Cancer. 65(2): 254-262. (1996). (PMID: 8567126).
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  87. Caulín, C.; Scholl, F.G.; Frontelo, P.; Gamallo, C.; Quintanilla, M. "Chronic exposure of cultured transformed mouse epidermal cells to transforming growth factor-beta 1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype.". Cell Growth Differ.. 6(8): 1027-1035. (1995). (PMID: 8547217).
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  88. Pizarro, A.; Gamallo, C.; Benito, N.; Palacios, J.; Quintanilla, M.; Cano, A.; Contreras, F. "Differential patterns of placental and epithelial cadherin expression in basal cell carcinoma and in the epidermis overlying tumours.". Br. J. Cancer. 72(2): 327-332. (1995). (PMID: 7640213).
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  89. Pizarro, A.; Benito, N.; Navarro, P.; Palacios, J.; Cano, A.; Quintanilla, M.; Contreras, F.; Gamallo, C. "E-cadherin expression in basal cell carcinoma.". Br. J. Cancer. 69(1): 157-162. (1994). (PMID: 8286199).
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  90. Gamallo, C.; Palacios, J.; Suarez, A.; Pizarro, A.; Navarro, P.; Quintanilla, M.; Cano, A. "Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma.". Am. J. Pathol.. 142(4): 987-993. (1993). (PMID: 7682767).
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  91. Caulín, C.; Bauluz, C.; Gandarillas, A.; Cano, A.; Quintanilla, M. "Changes in keratin expression during malignant progression of transformed mouse epidermal keratinocytes.". Exp. Cell Res.. 204(1): 11-21. (1993). (PMID: 7677983).
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  92. Larcher, F.; Bauluz, C.; Díaz-Guerra, M.; Quintanilla, M.; Conti, C.J.; Ballestín, C.; Jorcano, J.L. "Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas.". Mol. Carcinog.. 6(2): 112-121. (1992). (PMID: 1382441).
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  93. Gómez, M.; Navarro, P.; Quintanilla, M.; Cano, A. "Expression of alpha 6 beta 4 integrin increases during malignant conversion of mouse epidermal keratinocytes: association of beta 4 subunit to the cytokeratin fraction.". Exp. Cell Res.. 201(2): 250-261. (1992). (PMID: 1379191).
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  94. Inki, P.; Gomez, M.; Quintanilla, M.; Cano, A.; Jalkanen, M. "Expression of syndecan in transformed mouse keratinocytes.". Lab. Invest.. 67(2): 225-233. (1992). (PMID: 1501448).
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  95. Gandarillas, A.; Renart, J.; Quintanilla, M. "Biochemical characterization of Artemia ras p21.". Mol. Cell. Biochem.. 112(1): 29-33. (1992). (PMID: 1513332).
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  96. Diaz-Guerra, M.; Haddow, S.; Bauluz, C.; Jorcano, J.L.; Cano, A.; Balmain, A.; Quintanilla, M. "Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras gene alterations.". Cancer Res.. 52(3): 680-687. (1992). (PMID: 1370649).
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  97. Navarro, P.; Gómez, M.; Pizarro, A.; Gamallo, C.; Quintanilla, M.; Cano, A. "A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis.". J. Cell Biol.. 115(2): 517-533. (1991). (PMID: 1918152).
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  98. Quintanilla, M.; Haddow, S.; Jonas, D.; Jaffe, D.; Bowden, G.T.; Balmain, A. "Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo.". Carcinogenesis. 12(10): 1875-1881. (1991). (PMID: 1934268).
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  99. Díaz-Guerra, M.; Quintanilla, M.; Palmero, I.; Sastre, L.; Renart, J. "Differential expression of a gene highly homologous to c-ras during the development of the brine shrimp Artemia.". Biochem. Biophys. Res. Commun.. 162(2): 802-808. (1989). (PMID: 2502981).
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  100. Díaz, V.; Quintanilla, M.; Cruces, J.; Renart, J.; Sebastián, J. "Immunological relationships between Artemia RNA polymerases and between RNA polymerases II from different eukaryotic organisms.". Mol. Cell. Biochem.. 76(2): 123-131. (1987). (PMID: 3118183).
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  101. Quintanilla, M.; Brown, K.; Ramsden, M.; Balmain, A. "Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis.". Nature. 322(6074): 78-80. (1986). (PMID: 3014349).
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  102. Brown, K.; Quintanilla, M.; Ramsden, M.; Kerr, I.B.; Young, S.; Balmain, A. "v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis.". Cell. 46(3): 447-456. (1986). (PMID: 3015415).
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  103. Balmain, A.; Quintanilla, M.; Brown, K.; Ramsden, M. "An approach to the molecular mechanisms of cancer induction.". J. Pathol.. 149(1): 3-8. (1986). (PMID: 3088239).
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  104. Kerr, I.B.; Lee, F.D.; Quintanilla, M.; Balmain, A. "Immunocytochemical demonstration of p21 ras family oncogene product in normal mucosa and in premalignant and malignant tumours of the colorectum.". Br. J. Cancer. 52(5): 695-700. (1985). (PMID: 3904802).
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  105. Cruces, J.; Diaz, V.; Quintanilla, M.; Renart, J.; Sebastian, J. "Purification and subunit structure of RNA polymerase II from different stages of Artemia development.". Eur. J. Biochem.. 141(2): 279-282. (1984). (PMID: 6734599).
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  106. Quintanilla, M.; Renart, J. "Purification and characterization of a novel UpN-specific endoribonuclease VI from Artemia larvae.". J. Biol. Chem.. 257(21): 12594-12599. (1982). (PMID: 6813326).
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  107. Sillero, M.A.; Villalba, R.; Moreno, A.; Quintanilla, M.; Lobatón, C.D.; Sillero, A. "Dinucleosidetriphosphatase from rat liver. Purification and properties.". Eur. J. Biochem.. 76(2): 331-337. (1977). (PMID: 196848).
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  108. Vallejo, C.G.; Lobaton, C.D.; Quintanilla, M.; Sillero, A.; Sillero, M.A. "Dinucleosidasetetraphosphatase in rat liver and Artemia salina.". Biochim. Biophys. Acta. 438(1): 304-309. (1976). (PMID: 181087).
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