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PUBLICACIONES

 

 

spacerTrabajos Publicados por Angel Pascual García
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  1. Zambrano, A.; García-Carpizo, V.; Gallardo, M.E.; Villamuera, R.; Gómez-Ferrería, M.A.; Pascual, A.; Buisine, N.; Sachs, L.M.; Garesse, R.; Aranda, A. "The thyroid hormone receptor β induces DNA damage and premature senescence.". J. Cell Biol.. 204(1): 129-146. (2014). (PMID: 24395638).
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  2. Pascual, A.; Aranda, A. "Thyroid hormone receptors, cell growth and differentiation.". Biochim. Biophys. Acta. 1830(7): 3908-3916. (2013). (PMID: 22484490).
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  3. Contreras-Jurado, C.; Pascual, A. "Thyroid hormone regulation of APP (β-amyloid precursor protein) gene expression in brain and brain cultured cells.". Neurochem. Int.. 60(5): 484-487. (2012). (PMID: 22349409).
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  4. Bedó, G.; Pascual, A.; Aranda, A. "Early thyroid hormone-induced gene expression changes in N2a-β neuroblastoma cells.". J. Mol. Neurosci.. 45(2): 76-86. (2011). (PMID: 20506002).
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  5. Morte, B.; Martínez, T.; Zambrano, A.; Pascual, A. "Monocyte-mediated regulation of genes by the amyloid and prion peptides in SH-SY5Y neuroblastoma cells.". Neurochem. Int.. 58(6): 613-619. (2011). (PMID: 21303680).
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  6. Cuesta, A.; Zambrano, A.; López, E.; Pascual, A. "Thyroid hormones reverse the UV-induced repression of APP in neuroblastoma cells.". FEBS Lett.. 583(14): 2401-2406. (2009). (PMID: 19563806).
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  7. Cuesta, A.; Zambrano, A.; Royo, M.; Pascual, A. "The tumour suppressor p53 regulates the expression of amyloid precursor protein (APP).". Biochem. J.. 418(3): 643-650. (2009). (PMID: 19049493).
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  8. Martínez, T.; Pascual, A. "Identification of genes differentially expressed in SH-SY5Y neuroblastoma cells exposed to the prion peptide 106-126.". Eur. J. Neurosci.. 26(1): 51-59. (2007). (PMID: 17596192).
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  9. Martínez, T.; Pascual, A. "Gene expression profile in beta-amyloid-treated SH-SY5Y neuroblastoma cells.". Brain Res. Bull.. 72(4-6): 225-231. (2007). (PMID: 17452285).
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  10. Pascual, A.; Pariente, M.; Godínez, J.M.; Sánchez-Prieto, R.; Atienzar, M.; Segura, M.; Poblet, E. "High prevalence of human papillomavirus 16 in penile carcinoma.". Histol. Histopathol.. 22(2): 177-183. (2007). (PMID: 17149690).
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  11. Villa, A.; Santiago, J.; Belandia, B.; Pascual, A. "A response unit in the first exon of the beta-amyloid precursor protein gene containing thyroid hormone receptor and Sp1 binding sites mediates negative regulation by 3,5,3'-triiodothyronine.". Mol. Endocrinol.. 18(4): 863-873. (2004). (PMID: 14715929).
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  12. Ruiz-León, Y.; Pascual, A. "Regulation of beta-amyloid precursor protein expression by brain-derived neurotrophic factor involves activation of both the Ras and phosphatidylinositide 3-kinase signalling pathways.". J. Neurochem.. 88(4): 1010-1018. (2004). (PMID: 14756823).
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  13. Ruiz-León, Y.; Pascual, A. "Induction of tyrosine kinase receptor b by retinoic acid allows brain-derived neurotrophic factor-induced amyloid precursor protein gene expression in human SH-SY5Y neuroblastoma cells.". Neuroscience. 120(4): 1019-1026. (2003). (PMID: 12927207).
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  14. Villa, A.; Santiago, J.; García-Silva, S.; Ruiz-León, Y.; Pascual, A. "Serum is required for release of Alzheimer's amyloid precursor protein in neuroblastoma cells.". Neurochem. Int.. 41(4): 261-269. (2002). (PMID: 12106777).
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  15. Blanco-Colio, L.M.; Villa, A.; Ortego, M.; Hernández-Presa, M.A.; Pascual, A.; Plaza, J.J.; Egido, J. "3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.". Atherosclerosis. 161(1): 17-26. (2002). (PMID: 11882313).
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  16. Ruiz-León, Y.; Pascual, A. "Brain-derived neurotrophic factor stimulates beta-amyloid gene promoter activity by a Ras-dependent/AP-1-independent mechanism in SH-SY5Y neuroblastoma cells.". J. Neurochem.. 79(2): 278-285. (2001). (PMID: 11677255).
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  17. Aranda, A.; Pascual, A. "Nuclear hormone receptors and gene expression.". Physiol. Rev.. 81(3): 1269-1304. (2001). (PMID: 11427696).
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  18. Villa, A.; Latasa, M.J.; Pascual, A. "Nerve growth factor modulates the expression and secretion of beta-amyloid precursor protein through different mechanisms in PC12 cells.". J. Neurochem.. 77(4): 1077-1084. (2001). (PMID: 11359873).
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  19. Belandia, B.; Latasa, M.J.; Villa, A.; Pascual, A. "Thyroid hormone negatively regulates the transcriptional activity of the beta-amyloid precursor protein gene.". J. Biol. Chem.. 273(46): 30366-30371. (1998). (PMID: 9804800).
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  20. Latasa, M.J.; Belandia, B.; Pascual, A. "Thyroid hormones regulate beta-amyloid gene splicing and protein secretion in neuroblastoma cells.". Endocrinology. 139(6): 2692-2698. (1998). (PMID: 9607774).
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  21. Cosgaya, J.M.; Latasa, M.J.; Pascual, A. "Nerve growth factor and ras regulate beta-amyloid precursor protein gene expression in PC12 cells.". J. Neurochem.. 67(1): 98-9104. (1996). (PMID: 8667031).
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  22. Sanchez-Pacheco, A.; Perez, P.; Villa, A.; Pascual, A.; Aranda, A. "Nicotinamide analogs and DNA-damaging agents deplete thyroid hormone receptor and c-erbA mRNA levels in pituitary GH1 cells.". Mol. Cell. Endocrinol.. 91(1-2): 127-134. (1993). (PMID: 8386110).
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  23. Pérez, P.; Sánchez-Pacheco, A.; Pascual, A.; Aranda, A. "Retinoic acid decreases thyroid hormone receptor expression in pituitary GH1 cells.". Biochem. Biophys. Res. Commun.. 181(1): 9-15. (1991). (PMID: 1720314).
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  24. Aranda, A.; Pascual, A.; Copp, R.; Samuels, H. "Cholera toxin affects nuclear ADP-ribosylation in GH1 cells.". Biochem. Biophys. Res. Commun.. 150(1): 323-328. (1988). (PMID: 2827673).
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  25. Obregón, M.J.; Santisteban, P.; Rodríguez-Peña, A.; Pascual, A.; Cartagena, P.; Ruiz-Marcos, A.; Lamas, L.; Escobar del Rey, F.; Morreale de Escobar, G. "Cerebral hypothyroidism in rats with adult-onset iodine deficiency.". Endocrinology. 115(2): 614-624. (1984). (PMID: 6745172).
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  26. Ortiz-Caro, J.; Obregón, M.J.; Pascual, A.; Jolin, T. "Decreased T4 to T3 conversion in tissues of streptozotocin-diabetic rats.". Acta Endocrinol.. 106(1): 86-91. (1984). (PMID: 6328820).
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  27. Obregon, M.J.; Pascual, A.; Mallol, J.; Morreale de Escobar, G.; Escobar del Rey, F. "Evidence against a major role of L-thyroxine at the pituitary level: studies in rats treated with iopanoic acid (telepaque).". Endocrinology. 106(6): 1827-1836. (1980). (PMID: 7371594).
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  28. Pascual, A.; Obregon, M.J.; de Escobar, G.M. "Tyrosine hydroxylase and the conversion of L-thyroxine into 3',3,5-triiodo-L-thyronone in the rat.". Endocrinology. 104(6): 1574-1579. (1979). (PMID: 36273).
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  29. Obregon, M.J.; Pascual, A.; de Escobar, G.M.; Escobar del Rey, F. "Pituitary and plasma thyrotropin, thyroxine, and triiodothyronine after hyperthyroidism.". Endocrinology. 104(5): 1467-1473. (1979). (PMID: 108095).
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