Perez-Chacon, G.; Vincent-Fabert, C.; Zapata, J.M. "Editorial: Community series in mouse models of B cell malignancies, volume II.". Front Immunol. 15(): 1488601. (2024). (PMID: 39376568).
Martín-Antonio, B.; Blanco, B.; González-Murillo, Á.; Hidalgo, L.; Minguillón, J.; Pérez-Chacón, G.; , .; , . "Newer generations of multi-target CAR and STAb-T immunotherapeutics: NEXT CART Consortium as a cooperative effort to overcome current limitations.". Front Immunol. 15(): 1386856. (2024). (PMID: 38779672).
Perez-Chacon, G.; Vincent-Fabert, C.; Zapata, J.M. "Editorial: Mouse Models of B Cell Malignancies.". Front Immunol. 12(): 789901. (2021). (PMID: 34777400).
Perez-Chacon, G.; Zapata, J.M. "The Traf2DNxBCL2-tg Mouse Model of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Usage, Stereotypy, and Antigen-Specific HCDR3 Selection of Its Human Counterpart.". Front Immunol. 12(): 627602. (2021). (PMID: 33912159).
Compte, M.; Harwood, S.L.; Martínez-Torrecuadrada, J.; Perez-Chacon, G.; González-García, P.; Tapia-Galisteo, A.; Van Bergen En Henegouwen, P.M.P.; Sánchez, A.; Fabregat, I.; Sanz, L.; Zapata, J.M.; Alvarez-Vallina, L. "Case Report: An EGFR-Targeted 4-1BB-agonistic Trimerbody Does Not Induce Hepatotoxicity in Transgenic Mice With Liver Expression of Human EGFR.". Front Immunol. 11(): 614363. (2020). (PMID: 33488625).
Domínguez, J.M.; Pérez-Chacón, G.; Guillén, M.J.; Muñoz-Alonso, M.J.; Somovilla-Crespo, B.; Cibrián, D.; Acosta-Iborra, B.; Adrados, M.; Muñoz-Calleja, C.; Cuevas, C.; Sánchez-Madrid, F.; Avilés, P.; Zapata, J.M. "CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110.". J Hematol Oncol. 13(1): 32. (2020). (PMID: 32264921).
Ramos-Tomillero, I.; Pérez-Chacon, G.; Somovilla-Crespo, B.; Sánchez-Madrid, F.; Cuevas, C.; Zapata, J.M.; Domínguez, J.M.; Rodríguez, H.; Albericio, F. "From Ugi Multicomponent Reaction to Linkers for Bioconjugation.". ACS Omega. 5(13): 7424-7431. (2020). (PMID: 32280884).
Garaulet, G.; Pérez-Chacon, G.; Alarcón, H.; Alfranca, A.; Mulero, F.; Martínez-Torrecuadrada, J.; Zapata, J.M.; Rodríguez, A. "Intratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy.". Cancer Gene Ther.. 26(7-8): 216-233. (2019). (PMID: 30622324).
Perez-Chacon, G.; Adrados, M.; Vallejo-Cremades, M.T.; Lefebvre, S.; Reed, J.C.; Zapata, J.M. "Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice.". Front Immunol. 9(): 3114. (2018). (PMID: 30687320).
Compte, M.; Harwood, S.L.; Muñoz, I.G.; Navarro, R.; Zonca, M.; Perez-Chacon, G.; Erce-Llamazares, A.; Merino, N.; Tapia-Galisteo, A.; Cuesta, A.M.; Mikkelsen, K.; Caleiras, E.; Nuñez-Prado, N.; Aznar, M.A.; Lykkemark, S.; Martínez-Torrecuadrada, J.; Melero, I.; Blanco, F.J.; Bernardino de la Serna, J.; Zapata, J.M.; Sanz, L.; Alvarez-Vallina, L. "A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity.". Nat Commun. 9(1): 4809. (2018). (PMID: 30442944).
Zapata, J.M.; Perez-Chacon, G.; Carr-Baena, P.; Martinez-Forero, I.; Azpilikueta, A.; Otano, I.; Melero, I. "CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs.". Front Immunol. 9(): 2618. (2018). (PMID: 30524423).
Rebolleda, N.; Losada-Fernandez, I.; Perez-Chacon, G.; Castejon, R.; Rosado, S.; Morado, M.; Vallejo-Cremades, M.T.; Martinez, A.; Vargas-Nuñez, J.A.; Perez-Aciego, P. "Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model.". PLoS ONE. 11(4): e0154159. (2016). (PMID: 27101369).
Perez-Chacon, G.; Martinez-Laperche, C.; Rebolleda, N.; Somovilla-Crespo, B.; Muñoz-Calleja, C.; Buño, I.; Zapata, J.M. "Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.". Clin. Cancer Res.. 22(1): 134-145. (2016). (PMID: 26324744).
Lorenzo, C.; Pérez-Chacón, G.; Garaulet, G.; Mallorquín, Z.; Zapata, J.M.; Rodríguez, A. "Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines.". Cancer Gene Ther.. 22(11): 542-551. (2015). (PMID: 26450626).
Perez-Chacon, G.; de Los Rios, C.; Zapata, J.M. "Indole-3-carbinol induces cMYC and IAP-family downmodulation and promotes apoptosis of Epstein-Barr virus (EBV)-positive but not of EBV-negative Burkitt's lymphoma cell lines.". Pharmacol. Res.. 89(): 46-56. (2014). (PMID: 25180456).
Somovilla-Crespo, B.; Alfonso-Pérez, M.; Cuesta-Mateos, C.; Carballo-de Dios, C.; Beltrán, A.E.; Terrón, F.; Pérez-Villar, J.J.; Gamallo-Amat, C.; Pérez-Chacón, G.; Fernández-Ruiz, E.; Zapata, J.M.; Muñoz-Calleja, C. "Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma.". J Hematol Oncol. 6(): 89. (2013). (PMID: 24305507).
Martinez-Forero, I.; Azpilikueta, A.; Bolaños-Mateo, E.; Nistal-Villan, E.; Palazon, A.; Teijeira, A.; Perez-Chacon, G.; Morales-Kastresana, A.; Murillo, O.; Jure-Kunkel, M.; Zapata, J.M.; Melero, I. "T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.". J. Immunol.. 190(12): 6694-6706. (2013). (PMID: 23690480).
Pérez-Chacón, G.; Llobet, D.; Pardo, C.; Pindado, J.; Choi, Y.; Reed, J.C.; Zapata, J.M. "TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.". J. Immunol.. 189(2): 1053-1061. (2012). (PMID: 22711886).
Instituto de Investigaciones Biomédicas "Alberto Sols"
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