INVESTIGACIÓN

 
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PUBLICACIONES

 

 

spacerTrabajos Publicados por Juan Manuel Zapata Hernández
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  1. Perez-Chacon, G.; Vincent-Fabert, C.; Zapata, J.M. "Editorial: Community series in mouse models of B cell malignancies, volume II.". Front Immunol. 15(): 1488601. (2024). (PMID: 39376568).
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  2. Martín-Antonio, B.; Blanco, B.; González-Murillo, Á.; Hidalgo, L.; Minguillón, J.; Pérez-Chacón, G.; , .; , .; , . "Newer generations of multi-target CAR and STAb-T immunotherapeutics: NEXT CART Consortium as a cooperative effort to overcome current limitations.". Front Immunol. 15(): 1386856. (2024). (PMID: 38779672).
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  3. Vladimir de la Rosa, J.; Tabraue, C.; Huang, Z.; Orizaola, M.C.; Martin-Rodríguez, P.; Steffensen, K.R.; Zapata, J.M.; Boscá, L.; Tontonoz, P.; Alemany, S.; Treuter, E.; Castrillo, A. "Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses.". Adv Sci (Weinh). (): e2307201. (2024). (PMID: 38549193).
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  4. Glez-Vaz, J.; Azpilikueta, A.; Ochoa, M.C.; Olivera, I.; Gomis, G.; Cirella, A.; Luri-Rey, C.; Álvarez, M.; Pérez-Gracia, J.L.; Ciordia, S.; Eguren-Santamaria, I.; Alexandru, R.; Berraondo, P.; de Andrea, C.; Teijeira, Á.; Corrales, F.; Zapata, J.M.; Melero, I. "CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects.". Sci Adv. 9(33): eadf6692. (2023). (PMID: 37595047).
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  5. Perez-Chacon, G.; Vincent-Fabert, C.; Zapata, J.M. "Editorial: Mouse Models of B Cell Malignancies.". Front Immunol. 12(): 789901. (2021). (PMID: 34777400).
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  6. Aranda-Tavío, H.; Recio, C.; Martín-Acosta, P.; Guerra-Rodríguez, M.; Brito-Casillas, Y.; Blanco, R.; Junco, V.; León, J.; Montero, J.C.; Gandullo-Sánchez, L.; McNaughton-Smith, G.; Zapata, J.M.; Pandiella, A.; Amesty, A.; Estévez-Braun, A.; Fernández-Pérez, L.; Guerra, B. "JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia.". Biomed Pharmacother. 144(): 112330. (2021). (PMID: 34673425).
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  7. Perez-Chacon, G.; Zapata, J.M. "The Traf2DNxBCL2-tg Mouse Model of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Usage, Stereotypy, and Antigen-Specific HCDR3 Selection of Its Human Counterpart.". Front Immunol. 12(): 627602. (2021). (PMID: 33912159).
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  8. Compte, M.; Harwood, S.L.; Martínez-Torrecuadrada, J.; Perez-Chacon, G.; González-García, P.; Tapia-Galisteo, A.; Van Bergen En Henegouwen, P.M.P.; Sánchez, A.; Fabregat, I.; Sanz, L.; Zapata, J.M.; Alvarez-Vallina, L. "Case Report: An EGFR-Targeted 4-1BB-agonistic Trimerbody Does Not Induce Hepatotoxicity in Transgenic Mice With Liver Expression of Human EGFR.". Front Immunol. 11(): 614363. (2020). (PMID: 33488625).
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  9. Domínguez, J.M.; Pérez-Chacón, G.; Guillén, M.J.; Muñoz-Alonso, M.J.; Somovilla-Crespo, B.; Cibrián, D.; Acosta-Iborra, B.; Adrados, M.; Muñoz-Calleja, C.; Cuevas, C.; Sánchez-Madrid, F.; Avilés, P.; Zapata, J.M. "CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110.". J Hematol Oncol. 13(1): 32. (2020). (PMID: 32264921).
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  10. Ramos-Tomillero, I.; Pérez-Chacon, G.; Somovilla-Crespo, B.; Sánchez-Madrid, F.; Cuevas, C.; Zapata, J.M.; Domínguez, J.M.; Rodríguez, H.; Albericio, F. "From Ugi Multicomponent Reaction to Linkers for Bioconjugation.". ACS Omega. 5(13): 7424-7431. (2020). (PMID: 32280884).
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  11. Garaulet, G.; Pérez-Chacon, G.; Alarcón, H.; Alfranca, A.; Mulero, F.; Martínez-Torrecuadrada, J.; Zapata, J.M.; Rodríguez, A. "Intratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy.". Cancer Gene Ther.. 26(7-8): 216-233. (2019). (PMID: 30622324).
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  12. Perez-Chacon, G.; Adrados, M.; Vallejo-Cremades, M.T.; Lefebvre, S.; Reed, J.C.; Zapata, J.M. "Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice.". Front Immunol. 9(): 3114. (2018). (PMID: 30687320).
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  13. Compte, M.; Harwood, S.L.; Muñoz, I.G.; Navarro, R.; Zonca, M.; Perez-Chacon, G.; Erce-Llamazares, A.; Merino, N.; Tapia-Galisteo, A.; Cuesta, A.M.; Mikkelsen, K.; Caleiras, E.; Nuñez-Prado, N.; Aznar, M.A.; Lykkemark, S.; Martínez-Torrecuadrada, J.; Melero, I.; Blanco, F.J.; Bernardino de la Serna, J.; Zapata, J.M.; Sanz, L.; Alvarez-Vallina, L. "A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity.". Nat Commun. 9(1): 4809. (2018). (PMID: 30442944).
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  14. Zapata, J.M.; Perez-Chacon, G.; Carr-Baena, P.; Martinez-Forero, I.; Azpilikueta, A.; Otano, I.; Melero, I. "CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs.". Front Immunol. 9(): 2618. (2018). (PMID: 30524423).
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  15. Ramos-Tomillero, I.; Perez-Chacon, G.; Somovilla-Crespo, B.; Sanchez-Madrid, F.; Domínguez, J.M.; Cuevas, C.; Zapata, J.M.; Rodríguez, H.; Albericio, F. "Bioconjugation through Mesitylene Thiol Alkylation.". Bioconjug. Chem.. 29(4): 1199-1208. (2018). (PMID: 29433317).
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  16. Azpilikueta, A.; Bolaños, E.; Lang, V.; Labiano, S.; Aznar, M.A.; Etxeberria, I.; Teijeira, A.; Rodriguez-Ruiz, M.E.; Perez-Gracia, J.L.; Jure-Kunkel, M.; Zapata, J.M.; Rodriguez, M.S.; Melero, I. "Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4-1BB).". Oncoimmunology. 7(1): e1368605. (2017). (PMID: 29296520).
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  17. de la Cruz, A.; Vera-Zambrano, A.; Peraza, D.A.; Valenzuela, C.; Zapata, J.M.; Perez-Chacon, G.; Gonzalez, T. "Fludarabine Inhibits KV1.3 Currents in Human B Lymphocytes.". Front Pharmacol. 8(): 177. (2017). (PMID: 28408885).
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  18. Santacatterina, F.; Sánchez-Cenizo, L.; Formentini, L.; Mobasher, M.A.; Casas, E.; Rueda, C.B.; Martínez-Reyes, I.; Núñez de Arenas, C.; García-Bermúdez, J.; Zapata, J.M.; Sánchez-Aragó, M.; Satrústegui, J.; Valverde, Á.M.; Cuezva, J.M. "Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state.". Oncotarget. 7(1): 490-508. (2016). (PMID: 26595676).
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  19. Perez-Chacon, G.; Martinez-Laperche, C.; Rebolleda, N.; Somovilla-Crespo, B.; Muñoz-Calleja, C.; Buño, I.; Zapata, J.M. "Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.". Clin. Cancer Res.. 22(1): 134-145. (2016). (PMID: 26324744).
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  20. Lorenzo, C.; Pérez-Chacón, G.; Garaulet, G.; Mallorquín, Z.; Zapata, J.M.; Rodríguez, A. "Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines.". Cancer Gene Ther.. 22(11): 542-551. (2015). (PMID: 26450626).
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  21. Perez-Chacon, G.; de Los Rios, C.; Zapata, J.M. "Indole-3-carbinol induces cMYC and IAP-family downmodulation and promotes apoptosis of Epstein-Barr virus (EBV)-positive but not of EBV-negative Burkitt's lymphoma cell lines.". Pharmacol. Res.. 89(): 46-56. (2014). (PMID: 25180456).
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  22. Somovilla-Crespo, B.; Alfonso-Pérez, M.; Cuesta-Mateos, C.; Carballo-de Dios, C.; Beltrán, A.E.; Terrón, F.; Pérez-Villar, J.J.; Gamallo-Amat, C.; Pérez-Chacón, G.; Fernández-Ruiz, E.; Zapata, J.M.; Muñoz-Calleja, C. "Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma.". J Hematol Oncol. 6(): 89. (2013). (PMID: 24305507).
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  23. Martinez-Forero, I.; Azpilikueta, A.; Bolaños-Mateo, E.; Nistal-Villan, E.; Palazon, A.; Teijeira, A.; Perez-Chacon, G.; Morales-Kastresana, A.; Murillo, O.; Jure-Kunkel, M.; Zapata, J.M.; Melero, I. "T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.". J. Immunol.. 190(12): 6694-6706. (2013). (PMID: 23690480).
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  24. Pérez-Chacón, G.; Llobet, D.; Pardo, C.; Pindado, J.; Choi, Y.; Reed, J.C.; Zapata, J.M. "TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.". J. Immunol.. 189(2): 1053-1061. (2012). (PMID: 22711886).
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  25. Cuesta-Mateos, C.; López-Giral, S.; Alfonso-Pérez, M.; de Soria, V.G.; Loscertales, J.; Guasch-Vidal, S.; Beltrán, A.E.; Zapata, J.M.; Muñoz-Calleja, C. "Analysis of migratory and prosurvival pathways induced by the homeostatic chemokines CCL19 and CCL21 in B-cell chronic lymphocytic leukemia.". Exp. Hematol.. 38(9): 756-64, 764.e1-4. (2010). (PMID: 20488224).
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  26. Zapata, J.M.; Llobet, D.; Krajewska, M.; Lefebvre, S.; Kress, C.L.; Reed, J.C. "Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancer.". Blood. 113(19): 4595-4603. (2009). (PMID: 19074733).
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  27. Zapata, J.M.; Martínez-García, V.; Lefebvre, S. "Phylogeny of the TRAF/MATH domain.". Adv. Exp. Med. Biol.. 597(): 1-24. (2007). (PMID: 17633013).
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  28. Zapata, J.M.; Lefebvre, S.; Reed, J.C. "Targeting TRAfs for therapeutic intervention.". Adv. Exp. Med. Biol.. 597(): 188-201. (2007). (PMID: 17633027).
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  29. Kress, C.L.; Konopleva, M.; Martínez-García, V.; Krajewska, M.; Lefebvre, S.; Hyer, M.L.; McQueen, T.; Andreeff, M.; Reed, J.C.; Zapata, J.M. "Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.". PLoS ONE. 2(6): e559. (2007). (PMID: 17593960).
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  30. Fukushima, T.; Matsuzawa, S.; Kress, C.L.; Bruey, J.M.; Krajewska, M.; Lefebvre, S.; Zapata, J.M.; Ronai, Z.; Reed, J.C. "Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses.". Proc. Natl. Acad. Sci. U.S.A.. 104(15): 6371-6376. (2007). (PMID: 17404240).
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  31. Bailly-Maitre, B.; Bard-Chapeau, E.; Luciano, F.; Droin, N.; Bruey, J.M.; Faustin, B.; Kress, C.; Zapata, J.M.; Reed, J.C. "Mice lacking bi-1 gene show accelerated liver regeneration.". Cancer Res.. 67(4): 1442-1450. (2007). (PMID: 17308082).
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  32. Bailly-Maitre, B.; Fondevila, C.; Kaldas, F.; Droin, N.; Luciano, F.; Ricci, J.E.; Croxton, R.; Krajewska, M.; Zapata, J.M.; Kupiec-Weglinski, J.W.; Farmer, D.; Reed, J.C. "Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury.". Proc. Natl. Acad. Sci. U.S.A.. 103(8): 2809-2814. (2006). (PMID: 16478805).
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  33. Fukushima, T.; Zapata, J.M.; Singha, N.C.; Thomas, M.; Kress, C.L.; Krajewska, M.; Krajewski, S.; Ronai, Z.; Reed, J.C.; Matsuzawa, S. "Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint.". Immunity. 24(1): 29-39. (2006). (PMID: 16413921).
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  34. Samuel, T.; Welsh, K.; Lober, T.; Togo, S.H.; Zapata, J.M.; Reed, J.C. "Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases.". J. Biol. Chem.. 281(2): 1080-1090. (2006). (PMID: 16282325).
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  35. Hyer, M.L.; Croxton, R.; Krajewska, M.; Krajewski, S.; Kress, C.L.; Lu, M.; Suh, N.; Sporn, M.B.; Cryns, V.L.; Zapata, J.M.; Reed, J.C. "Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.". Cancer Res.. 65(11): 4799-4808. (2005). (PMID: 15930300).
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  36. Samuel, T.; Okada, K.; Hyer, M.; Welsh, K.; Zapata, J.M.; Reed, J.C. "cIAP1 Localizes to the nuclear compartment and modulates the cell cycle.". Cancer Res.. 65(1): 210-218. (2005). (PMID: 15665297).
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  37. Zapata, J.M.; Krajewska, M.; Morse, H.C.; Choi, Y.; Reed, J.C. "TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice.". Proc. Natl. Acad. Sci. U.S.A.. 101(47): 16600-16605. (2004). (PMID: 15545599).
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  38. Lo, J.F.; Hayashi, M.; Woo-Kim, S.; Tian, B.; Huang, J.F.; Fearns, C.; Takayama, S.; Zapata, J.M.; Yang, Y.; Lee, J.D. "Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.". Mol. Cell. Biol.. 24(6): 2226-2236. (2004). (PMID: 14993262).
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  39. Kermer, P.; Digicaylioglu, M.H.; Kaul, M.; Zapata, J.M.; Krajewska, M.; Stenner-Liewen, F.; Takayama, S.; Krajewski, S.; Lipton, S.A.; Reed, J.C. "BAG1 over-expression in brain protects against stroke.". Brain Pathol.. 13(4): 495-506. (2003). (PMID: 14655755).
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  40. Reed, J.C.; Doctor, K.; Rojas, A.; Zapata, J.M.; Stehlik, C.; Fiorentino, L.; Damiano, J.; Roth, W.; Matsuzawa, S.; Newman, R.; Takayama, S.; Marusawa, H.; Xu, F.; Salvesen, G.; Godzik, A.; , .; , . "Comparative analysis of apoptosis and inflammation genes of mice and humans.". Genome Res.. 13(6B): 1376-1388. (2003). (PMID: 12819136).
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  41. Zapata, J.M. "TNF-receptor-associated factors as targets for drug development.". Expert Opin. Ther. Targets. 7(3): 411-425. (2003). (PMID: 12783577).
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  42. Cuezva, J.M.; Krajewska, M.; de Heredia, M.L.; Krajewski, S.; Santamaría, G.; Kim, H.; Zapata, J.M.; Marusawa, H.; Chamorro, M.; Reed, J.C. "The bioenergetic signature of cancer: a marker of tumor progression.". Cancer Res.. 62(22): 6674-6681. (2002). (PMID: 12438266).
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  43. Pedersen, I.M.; Kitada, S.; Schimmer, A.; Kim, Y.; Zapata, J.M.; Charboneau, L.; Rassenti, L.; Andreeff, M.; Bennett, F.; Sporn, M.B.; Liotta, L.D.; Kipps, T.J.; Reed, J.C. "The triterpenoid CDDO induces apoptosis in refractory CLL B cells.". Blood. 100(8): 2965-2972. (2002). (PMID: 12351409).
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  44. Pedersen, I.M.; Kitada, S.; Leoni, L.M.; Zapata, J.M.; Karras, J.G.; Tsukada, N.; Kipps, T.J.; Choi, Y.S.; Bennett, F.; Reed, J.C. "Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1.". Blood. 100(5): 1795-1801. (2002). (PMID: 12176902).
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  45. Krajewska, M.; Zapata, J.M.; Meinhold-Heerlein, I.; Hedayat, H.; Monks, A.; Bettendorf, H.; Shabaik, A.; Bubendorf, L.; Kallioniemi, O.P.; Kim, H.; Reifenberger, G.; Reed, J.C.; Krajewski, S. "Expression of Bcl-2 family member Bid in normal and malignant tissues.". Neoplasia. 4(2): 129-140. (2002). (PMID: 11896568).
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  46. Zapata, J.M.; Reed, J.C. "TRAF1: lord without a RING.". Sci. STKE. 2002(133): pe27. (2002). (PMID: 12023442).
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  47. Kermer, P.; Krajewska, M.; Zapata, J.M.; Takayama, S.; Mai, J.; Krajewski, S.; Reed, J.C. "Bag1 is a regulator and marker of neuronal differentiation.". Cell Death Differ.. 9(4): 405-413. (2002). (PMID: 11965493).
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  48. Stenner-Liewen, F.; Liewen, H.; Zapata, J.M.; Pawlowski, K.; Godzik, A.; Reed, J.C. "CADD, a Chlamydia protein that interacts with death receptors.". J. Biol. Chem.. 277(12): 9633-9636. (2002). (PMID: 11805081).
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  49. Krajewska, M.; Mai, J.K.; Zapata, J.M.; Ashwell, K.W.; Schendel, S.L.; Reed, J.C.; Krajewski, S. "Dynamics of expression of apoptosis-regulatory proteins Bid, Bcl-2, Bcl-X, Bax and Bak during development of murine nervous system.". Cell Death Differ.. 9(2): 145-157. (2002). (PMID: 11840165).
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  50. Zapata, J.M.; Pawlowski, K.; Haas, E.; Ware, C.F.; Godzik, A.; Reed, J.C. "A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.". J. Biol. Chem.. 276(26): 24242-24252. (2001). (PMID: 11279055).
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  51. Meinhold-Heerlein, I.; Stenner-Liewen, F.; Liewen, H.; Kitada, S.; Krajewska, M.; Krajewski, S.; Zapata, J.M.; Monks, A.; Scudiero, D.A.; Bauknecht, T.; Reed, J.C. "Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer.". Am. J. Pathol.. 158(4): 1335-1344. (2001). (PMID: 11290551).
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  52. Zapata, J.M.; Krajewska, M.; Krajewski, S.; Kitada, S.; Welsh, K.; Monks, A.; McCloskey, N.; Gordon, J.; Kipps, T.J.; Gascoyne, R.D.; Shabaik, A.; Reed, J.C. "TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies.". J. Immunol.. 165(9): 5084-5096. (2000). (PMID: 11046039).
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  53. Kitada, S.; Zapata, J.M.; Andreeff, M.; Reed, J.C. "Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia.". Blood. 96(2): 393-397. (2000). (PMID: 10887097).
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  54. Zapata, J.M.; Matsuzawa, S.; Godzik, A.; Leo, E.; Wasserman, S.A.; Reed, J.C. "The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity.". J. Biol. Chem.. 275(16): 12102-12107. (2000). (PMID: 10766844).
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  55. Leo, E.; Zapata, J.M.; Reed, J.C. "CD40-mediated activation of Ig-Cgamma1- and Ig-cepsilon germ-line promoters involves multiple TRAF family proteins.". Eur. J. Immunol.. 29(12): 3908-3913. (1999). (PMID: 10601998).
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  56. Ye, X.; Mehlen, P.; Rabizadeh, S.; VanArsdale, T.; Zhang, H.; Shin, H.; Wang, J.J.; Leo, E.; Zapata, J.; Hauser, C.A.; Reed, J.C.; Bredesen, D.E. "TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction.". J. Biol. Chem.. 274(42): 30202-30208. (1999). (PMID: 10514511).
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  57. Kitada, S.; Zapata, J.M.; Andreeff, M.; Reed, J.C. "Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia.". Br. J. Haematol.. 106(4): 995-991004. (1999). (PMID: 10520003).
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  58. Leo, E.; Welsh, K.; Matsuzawa, S.; Zapata, J.M.; Kitada, S.; Mitchell, R.S.; Ely, K.R.; Reed, J.C. "Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation.". J. Biol. Chem.. 274(32): 22414-22422. (1999). (PMID: 10428814).
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  59. Gil, J.; Yamamoto, H.; Zapata, J.M.; Reed, J.C.; Perucho, M. "Impairment of the proapoptotic activity of Bax by missense mutations found in gastrointestinal cancers.". Cancer Res.. 59(9): 2034-2037. (1999). (PMID: 10232581).
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  60. Tamm, I.; Paternostro, G.; Zapata, J.M. "Treatment of acute promyelocytic leukemia with arsenic trioxide.". N. Engl. J. Med.. 340(13): 1043; author reply 1044-5. (1999). (PMID: 10189285).
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  61. Krajewski, S.; Krajewska, M.; Turner, B.C.; Pratt, C.; Howard, B.; Zapata, J.M.; Frenkel, V.; Robertson, S.; Ionov, Y.; Yamamoto, H.; Perucho, M.; Takayama, S.; Reed, J.C. "Prognostic significance of apoptosis regulators in breast cancer.". Endocr. Relat. Cancer. 6(1): 29-40. (1999). (PMID: 10732784).
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  62. Takayama, S.; Krajewski, S.; Krajewska, M.; Kitada, S.; Zapata, J.M.; Kochel, K.; Knee, D.; Scudiero, D.; Tudor, G.; Miller, G.J.; Miyashita, T.; Yamada, M.; Reed, J.C. "Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines.". Cancer Res.. 58(14): 3116-3131. (1998). (PMID: 9679980).
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  63. Krajewska, M.; Krajewski, S.; Zapata, J.M.; Van Arsdale, T.; Gascoyne, R.D.; Berern, K.; McFadden, D.; Shabaik, A.; Hugh, J.; Reynolds, A.; Clevenger, C.V.; Reed, J.C. "TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues.". Am. J. Pathol.. 152(6): 1549-1561. (1998). (PMID: 9626059).
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  64. Kitada, S.; Andersen, J.; Akar, S.; Zapata, J.M.; Takayama, S.; Krajewski, S.; Wang, H.G.; Zhang, X.; Bullrich, F.; Croce, C.M.; Rai, K.; Hines, J.; Reed, J.C. "Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.". Blood. 91(9): 3379-3389. (1998). (PMID: 9558396).
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  65. Matsuzawa, S.; Takayama, S.; Froesch, B.A.; Zapata, J.M.; Reed, J.C. "p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1.". EMBO J.. 17(10): 2736-2747. (1998). (PMID: 9582267).
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  66. Zapata, J.M.; Takahashi, R.; Salvesen, G.S.; Reed, J.C. "Granzyme release and caspase activation in activated human T-lymphocytes.". J. Biol. Chem.. 273(12): 6916-6920. (1998). (PMID: 9506996).
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  67. Kitada, S.; Krajewska, M.; Zhang, X.; Scudiero, D.; Zapata, J.M.; Wang, H.G.; Shabaik, A.; Tudor, G.; Krajewski, S.; Myers, T.G.; Johnson, G.S.; Sausville, E.A.; Reed, J.C. "Expression and location of pro-apoptotic Bcl-2 family protein BAD in normal human tissues and tumor cell lines.". Am. J. Pathol.. 152(1): 51-61. (1998). (PMID: 9422523).
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  68. Zapata, J.M.; Krajewska, M.; Krajewski, S.; Huang, R.P.; Takayama, S.; Wang, H.G.; Adamson, E.; Reed, J.C. "Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors.". Breast Cancer Res. Treat.. 47(2): 129-140. (1998). (PMID: 9497101).
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  69. Krajewski, S.; Zapata, J.M.; Krajewska, M.; VanArsdale, T.; Shabaik, A.; Gascoyne, R.D.; Reed, J.C. "Immunohistochemical analysis of in vivo patterns of TRAF-3 expression, a member of the TNF receptor-associated factor family.". J. Immunol.. 159(12): 5841-5852. (1997). (PMID: 9550380).
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  70. Krajewski, S.; Gascoyne, R.D.; Zapata, J.M.; Krajewska, M.; Kitada, S.; Chhanabhai, M.; Horsman, D.; Berean, K.; Piro, L.D.; Fugier-Vivier, I.; Liu, Y.J.; Wang, H.G.; Reed, J.C. "Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.". Blood. 89(10): 3817-3825. (1997). (PMID: 9160689).
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  72. Eliopoulos, A.G.; Dawson, C.W.; Mosialos, G.; Floettmann, J.E.; Rowe, M.; Armitage, R.J.; Dawson, J.; Zapata, J.M.; Kerr, D.J.; Wakelam, M.J.; Reed, J.C.; Kieff, E.; Young, L.S. "CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: involvement of TRAF3 as a common mediator.". Oncogene. 13(10): 2243-2254. (1996). (PMID: 8950992).
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  73. Pérez-Villar, J.J.; Zapata, J.M.; Melero, I.; Postigo, A.; Sánchez-Madrid, E.; López-Botet, M. "Expression and function of alpha 4/beta 7 integrin on human natural killer cells.". Immunology. 89(1): 96-9104. (1996). (PMID: 8911146).
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  76. Arroyo, A.G.; Campanero, M.R.; Sánchez-Mateos, P.; Zapata, J.M.; Ursa, M.A.; del Pozo, M.A.; Sánchez-Madrid, F. "Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase.". J. Cell Biol.. 126(5): 1277-1286. (1994). (PMID: 7520448).
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  77. Zapata, J.M.; Martínez, M.A.; Sierra, J.M. "Purification and characterization of eukaryotic polypeptide chain initiation factor 4F from Drosophila melanogaster embryos.". J. Biol. Chem.. 269(27): 18047-18052. (1994). (PMID: 8027064).
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  78. Sierra, J.M.; Zapata, J.M. "Translational regulation of the heat shock response.". Mol. Biol. Rep.. 19(3): 211-220. (1994). (PMID: 7969109).
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  79. Zapata, J.M.; Pulido, R.; Acevedo, A.; Sánchez-Madrid, F.; de Landázuri, M.O. "Human CD45RC specificity. A novel marker for T cells at different maturation and activation stages.". J. Immunol.. 152(8): 3852-3861. (1994). (PMID: 8144955).
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