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PUBLICACIONES

 

 

spacerTrabajos Publicados por Beatriz Morte Molina
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  1. Cotrina-Vinagre, F.J.; Rodríguez-García, M.E.; Del Pozo-Filíu, L.; Hernández-Laín, A.; Arteche-López, A.; Morte, B.; Sevilla, M.; Pérez-Jurado, L.A.; Quijada-Fraile, P.; Camacho, A.; Martínez-Azorín, F. "Expanding the genetic and phenotypic spectrum of congenital myasthenic syndrome: new homozygous VAMP1 splicing variants in 2 novel individuals.". J Hum Genet. (): . (2024). (PMID: 38355957).
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  2. Bernal, J.; Morte, B.; Diez, D. "Thyroid hormone regulators in human cerebral cortex development.". J Endocrinol. 255(3): R27-R36. (2022). (PMID: 36219489).
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  3. Diez, D.; Morte, B.; Bernal, J. "Single-Cell Transcriptome Profiling of Thyroid Hormone Effectors in the Human Fetal Neocortex: Expression of SLCO1C1, DIO2, and THRB in Specific Cell Types.". Thyroid. (): . (2021). (PMID: 34114484).
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  4. Gil-Ibañez, P.; Belinchon, M.M.; Obregon, M.J.; Morte, B.; Bernal, J. "Is the intrinsic genomic activity of thyroxine relevant in vivo? Insight from the effects on gene expression in primary cerebrocortical and neuroblastoma cells.". Thyroid. (): . (2017). (PMID: 28605984).
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  5. Gil-Ibañez, P.; García-García, F.; Dopazo, J.; Bernal, J.; Morte, B. "Global Transcriptome Analysis of Primary Cerebrocortical Cells: Identification of Genes Regulated by Triiodothyronine in Specific Cell Types.". Cereb. Cortex. 27(1): 706-717. (2017). (PMID: 26534908).
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  6. Bárez-López, S.; Obregon, M.J.; Martínez-de-Mena, R.; Bernal, J.; Guadaño-Ferraz, A.; Morte, B. "Effect of Triiodothyroacetic Acid Treatment in Mct8 Deficiency: A Word of Caution.". Thyroid. 26(5): 618-626. (2016). (PMID: 26701289).
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  7. Bernal, J.; Guadaño-Ferraz, A.; Morte, B. "Thyroid hormone transporters-functions and clinical implications.". Nat Rev Endocrinol. 11(12): 690. (2015). (PMID: 26485690).
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  8. Bernal, J.; Guadaño-Ferraz, A.; Morte, B. "Thyroid hormone transporters--functions and clinical implications.". Nat Rev Endocrinol. 11(9): 506. (2015). (PMID: 26149615).
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  9. Bernal, J.; Guadaño-Ferraz, A.; Morte, B. "Thyroid hormone transporters--functions and clinical implications.". Nat Rev Endocrinol. 11(7): 406-417. (2015). (PMID: 25942657).
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  10. Aguilera, Ó.; González-Sancho, J.M.; Zazo, S.; Rincón, R.; Fernández, A.F.; Tapia, O.; Canals, F.; Morte, B.; Calvanese, V.; Orgaz, J.L.; Niell, N.; Aguilar, S.; Freije, J.M.; Graña, O.; Pisano, D.G.; Borrero, A.; Martínez-Useros, J.; Jiménez, B.; Fraga, M.F.; García-Foncillas, J.; López-Otín, C.; Lafarga, M.; Rojo, F.; Muñoz, A. "Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.". Oncotarget. 6(8): 5903-5917. (2015). (PMID: 25788273).
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  11. Navarro, D.; Alvarado, M.; Morte, B.; Berbel, D.; Sesma, J.; Pacheco, P.; Morreale de Escobar, G.; Bernal, J.; Berbel, P. "Late maternal hypothyroidism alters the expression of Camk4 in neocortical subplate neurons: a comparison with Nurr1 labeling.". Cereb. Cortex. 24(10): 2694-2706. (2014). (PMID: 23680840).
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  12. Núñez, B.; Martínez de Mena, R.; Obregon, M.J.; Font-Llitjós, M.; Nunes, V.; Palacín, M.; Dumitrescu, A.M.; Morte, B.; Bernal, J. "Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation.". PLoS ONE. 9(5): e96915. (2014). (PMID: 24819605).
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  13. Morte, B.; Bernal, J. "Thyroid hormone action: astrocyte-neuron communication.". Front Endocrinol (Lausanne). 5(): 82. (2014). (PMID: 24910631).
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  14. Bernal, J.; Morte, B. "Thyroid hormone receptor activity in the absence of ligand: physiological and developmental implications.". Biochim. Biophys. Acta. 1830(7): 3893-3899. (2013). (PMID: 22554916).
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  15. Gil-Ibañez, P.; Morte, B.; Bernal, J. "Role of thyroid hormone receptor subtypes α and β on gene expression in the cerebral cortex and striatum of postnatal mice.". Endocrinology. 154(5): 1940-1947. (2013). (PMID: 23493375).
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  16. Hernandez, A.; Morte, B.; Belinchón, M.M.; Ceballos, A.; Bernal, J. "Critical role of types 2 and 3 deiodinases in the negative regulation of gene expression by T₃in the mouse cerebral cortex.". Endocrinology. 153(6): 2919-2928. (2012). (PMID: 22523155).
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  17. Sánchez-Bailón, M.P.; Calcabrini, A.; Gómez-Domínguez, D.; Morte, B.; Martín-Forero, E.; Gómez-López, G.; Molinari, A.; Wagner, K.U.; Martín-Pérez, J. "Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells.". Cell. Signal.. 24(6): 1276-1286. (2012). (PMID: 22570868).
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  18. Resmini, E.; Morte, B.; Sorianello, E.; Gallardo, E.; de Luna, N.; Illa, I.; Zorzano, A.; Bernal, J.; Webb, S.M. "Identification of novel GH-regulated genes in C2C12 cells.". Horm. Metab. Res.. 43(13): 919-930. (2011). (PMID: 22072432).
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  19. Morte, B.; Martínez, T.; Zambrano, A.; Pascual, A. "Monocyte-mediated regulation of genes by the amyloid and prion peptides in SH-SY5Y neuroblastoma cells.". Neurochem. Int.. 58(6): 613-619. (2011). (PMID: 21303680).
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  20. Grijota-Martínez, C.; Díez, D.; Morreale de Escobar, G.; Bernal, J.; Morte, B. "Lack of action of exogenously administered T3 on the fetal rat brain despite expression of the monocarboxylate transporter 8.". Endocrinology. 152(4): 1713-1721. (2011). (PMID: 21303950).
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  21. Grijota-Martínez, C.; Samarut, E.; Scanlan, T.S.; Morte, B.; Bernal, J. "In vivo activity of the thyroid hormone receptor beta- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain.". Endocrinology. 152(3): 1136-1142. (2011). (PMID: 21239431).
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  22. Morte, B.; Ceballos, A.; Diez, D.; Grijota-Martínez, C.; Dumitrescu, A.M.; Di Cosmo, C.; Galton, V.A.; Refetoff, S.; Bernal, J. "Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.". Endocrinology. 151(5): 2381-2387. (2010). (PMID: 20211971).
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  23. Morte, B.; Díez, D.; Ausó, E.; Belinchón, M.M.; Gil-Ibáñez, P.; Grijota-Martínez, C.; Navarro, D.; de Escobar, G.M.; Berbel, P.; Bernal, J. "Thyroid hormone regulation of gene expression in the developing rat fetal cerebral cortex: prominent role of the Ca2+/calmodulin-dependent protein kinase IV pathway.". Endocrinology. 151(2): 810-820. (2010). (PMID: 20056827).
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  24. Ceballos, A.; Belinchon, M.M.; Sanchez-Mendoza, E.; Grijota-Martinez, C.; Dumitrescu, A.M.; Refetoff, S.; Morte, B.; Bernal, J. "Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine.". Endocrinology. 150(5): 2491-2496. (2009). (PMID: 19147674).
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  25. Diez, D.; Grijota-Martinez, C.; Agretti, P.; De Marco, G.; Tonacchera, M.; Pinchera, A.; de Escobar, G.M.; Bernal, J.; Morte, B. "Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum.". Endocrinology. 149(8): 3989-4000. (2008). (PMID: 18467437).
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  26. Manzano, J.; Cuadrado, M.; Morte, B.; Bernal, J. "Influence of thyroid hormone and thyroid hormone receptors in the generation of cerebellar gamma-aminobutyric acid-ergic interneurons from precursor cells.". Endocrinology. 148(12): 5746-5751. (2007). (PMID: 17761765).
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  27. Manzano, J.; Bernal, J.; Morte, B. "Influence of thyroid hormones on maturation of rat cerebellar astrocytes.". Int. J. Dev. Neurosci.. 25(3): 171-179. (2007). (PMID: 17408906).
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  28. Martin, G.; Guadaño-Ferraz, A.; Morte, B.; Ahmed, S.; Koob, G.F.; De Lecea, L.; Siggins, G.R. "Chronic morphine treatment alters N-methyl-D-aspartate receptors in freshly isolated neurons from nucleus accumbens.". J. Pharmacol. Exp. Ther.. 311(1): 265-273. (2004). (PMID: 15263066).
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  29. Morte, B.; Manzano, J.; Scanlan, T.S.; Vennström, B.; Bernal, J. "Aberrant maturation of astrocytes in thyroid hormone receptor alpha 1 knockout mice reveals an interplay between thyroid hormone receptor isoforms.". Endocrinology. 145(3): 1386-1391. (2004). (PMID: 14630717).
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  30. Manzano, J.; Morte, B.; Scanlan, T.S.; Bernal, J. "Differential effects of triiodothyronine and the thyroid hormone receptor beta-specific agonist GC-1 on thyroid hormone target genes in the b ain.". Endocrinology. 144(12): 5480-5487. (2003). (PMID: 12959999).
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  31. Bernal, J.; Guadaño-Ferraz, A.; Morte, B. "Perspectives in the study of thyroid hormone action on brain development and function.". Thyroid. 13(11): 1005-1012. (2003). (PMID: 14651784).
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  32. Morte, B.; Manzano, J.; Scanlan, T.; Vennström, B.; Bernal, J. "Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism.". Proc. Natl. Acad. Sci. U.S.A.. 99(6): 3985-3989. (2002). (PMID: 11891331).
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  33. Vargiu, P.; Morte, B.; Manzano, J.; Perez, J.; de Abajo, R.; Gregor Sutcliffe, J.; Bernal, J. "Thyroid hormone regulation of rhes, a novel Ras homolog gene expressed in the striatum.". Brain Res. Mol. Brain Res.. 94(1-2): 1-8. (2001). (PMID: 11597759).
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  34. Morte, B.; Martínez de Arrieta, C.; Manzano, J.; Coloma, A.; Bernal, J. "Identification of a cis-acting element that interferes with thyroid hormone induction of the neurogranin (NRGN) gene.". FEBS Lett.. 464(3): 179-183. (1999). (PMID: 10618501).
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  35. Martínez de Arrieta, C.; Morte, B.; Coloma, A.; Bernal, J. "The human RC3 gene homolog, NRGN contains a thyroid hormone-responsive element located in the first intron.". Endocrinology. 140(1): 335-343. (1999). (PMID: 9886843).
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  36. de Arrieta, C.M.; Morte, B.; Coloma, A.; Bernal, J. "The Human RC3 Gene Homolog, NRGN Contains a Thyroid Hormone-Responsive Element Located in the First Intron* * This work was supported by grants from Fundación Ramon Areces and DGICYT (PM95-0019).". Endocrinology. 140(1): 335-343. (1999). (PMID: 28200699).
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  37. Guadaño-Ferraz, A.; Escámez, M.J.; Morte, B.; Vargiu, P.; Bernal, J. "Transcriptional induction of RC3/neurogranin by thyroid hormone: differential neuronal sensitivity is not correlated with thyroid hormone receptor distribution in the brain.". Brain Res. Mol. Brain Res.. 49(1-2): 37-44. (1997). (PMID: 9387861).
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  38. Morte, B.; Iñiguez, M.A.; Lorenzo, P.I.; Bernal, J. "Thyroid hormone-regulated expression of RC3/neurogranin in the immortalized hypothalamic cell line GT1-7.". J. Neurochem.. 69(3): 902-909. (1997). (PMID: 9282911).
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  39. Iniguez, M.A.; De Lecea, L.; Guadano-Ferraz, A.; Morte, B.; Gerendasy, D.; Sutcliffe, J.G.; Bernal, J. "Cell-specific effects of thyroid hormone on RC3/neurogranin expression in rat brain.". Endocrinology. 137(3): 1032-1041. (1996). (PMID: 8603571).
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  40. Iñiguez, M.A.; Morte, B.; Rodriguez-Peña, A.; Muñoz, A.; Gerendasy, D.; Sutcliffe, J.G.; Bernal, J. "Characterization of the promoter region and flanking sequences of the neuron-specific gene RC3 (neurogranin).". Brain Res. Mol. Brain Res.. 27(2): 205-214. (1994). (PMID: 7898304).
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