Gil-Fernández, M.; Navarro-García, J.A.; Val-Blasco, A.; González-Lafuente, L.; Martínez, J.C.; Rueda, A.; Tamayo, M.; Morgado, J.L.; Zaragoza, C.; Ruilope, L.M.; Delgado, C.; Ruiz-Hurtado, G.; Fernández-Velasco, M. "Genetic Deletion of NOD1 Prevents Cardiac Ca2+ Mishandling Induced by Experimental Chronic Kidney Disease.". Int J Mol Sci. 21(22): . (2020). (PMID: 33238586).
Ruiz-Hurtado, G.; Rueda, A.; Pereira, L.; Fernández-Velasco, M. "Editorial: Evolving Picture of Calcium Handling in Cardiac Disease.". Front Physiol. 11(): 1013. (2020). (PMID: 33013442).
Tamayo, M.; Martín-Nunes, L.; Val-Blasco, A.; G M-Piedras, M.J.; Navarro-García, J.A.; Lage, E.; Prieto, P.; Ruiz-Hurtado, G.; Fernández-Velasco, M.; Delgado, C. "Beneficial effects of paricalcitol on cardiac dysfunction and remodelling in a model of established heart failure.". Br. J. Pharmacol.. 177(14): 3273-3290. (2020). (PMID: 32154912).
Val-Blasco, A.; Navarro-García, J.A.; Tamayo, M.; Piedras, M.J.; Prieto, P.; Delgado, C.; Ruiz-Hurtado, G.; Rozas-Romero, L.; Gil-Fernández, M.; Zaragoza, C.; Boscá, L.; Fernández-Velasco, M. "Deficiency of NOD1 Improves the β-Adrenergic Modulation of Ca2+ Handling in a Mouse Model of Heart Failure.". Front Physiol. 9(): 702. (2018). (PMID: 29962957).
Navarro-García, J.A.; Fernández-Velasco, M.; Delgado, C.; Delgado, J.F.; Kuro-O, M.; Ruilope, L.M.; Ruiz-Hurtado, G. "PTH, vitamin D, and the FGF-23-klotho axis and heart: Going beyond the confines of nephrology.". Eur. J. Clin. Invest.. 48(4): . (2018). (PMID: 29394451).
Brea, R.; Motiño, O.; Francés, D.; García-Monzón, C.; Vargas, J.; Fernández-Velasco, M.; Boscá, L.; Casado, M.; Martín-Sanz, P.; Agra, N. "PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p.". Biochim. Biophys. Acta. 1864(2): 325-337. (2018). (PMID: 29109031).
Tamayo, M.; Manzanares, E.; Bas, M.; Martín-Nunes, L.; Val-Blasco, A.; Jesús Larriba, M.; Fernández-Velasco, M.; Delgado, C. "Calcitriol (1,25-dihydroxyvitamin D3) increases L-type calcium current via protein kinase A signaling and modulates calcium cycling and contractility in isolated mouse ventricular myocytes.". Heart Rhythm. 14(3): 432-439. (2017). (PMID: 27989685).
Ruiz-Hurtado, G.; García-Prieto, C.F.; Pulido-Olmo, H.; Velasco-Martín, J.P.; Villa-Valverde, P.; Fernández-Valle, M.E.; Boscá, L.; Fernández-Velasco, M.; Regadera, J.; Somoza, B.; Fernández-Alfonso, M.S. "Mild and Short-Term Caloric Restriction Prevents Obesity-Induced Cardiomyopathy in Young Zucker Rats without Changing in Metabolites and Fatty Acids Cardiac Profile.". Front Physiol. 8(): 42. (2017). (PMID: 28203206).
Cuadrado-Berrocal, I.; Gómez-Gaviro, M.V.; Benito, Y.; Barrio, A.; Bermejo, J.; Fernández-Santos, M.E.; Sánchez, P.L.; Desco, M.; Fernández-Avilés, F.; Fernández-Velasco, M.; Boscá, L.; de Las Heras, B. "A labdane diterpene exerts ex vivo and in vivo cardioprotection against post-ischemic injury: involvement of AKT-dependent mechanisms.". Biochem. Pharmacol.. 93(4): 428-439. (2015). (PMID: 25557296).
Prieto, P.; Vallejo-Cremades, M.T.; Benito, G.; González-Peramato, P.; Francés, D.; Agra, N.; Terrón, V.; Gónzalez-Ramos, S.; Delgado, C.; Ruiz-Gayo, M.; Pacheco, I.; Velasco-Martín, J.P.; Regadera, J.; Martín-Sanz, P.; López-Collazo, E.; Boscá, L.; Fernández-Velasco, M. "NOD1 receptor is up-regulated in diabetic human and murine myocardium.". Clin. Sci.. 127(12): 665-677. (2014). (PMID: 24934088).
Fernández-Ruiz, I.; Arnalich, F.; Cubillos-Zapata, C.; Hernández-Jiménez, E.; Moreno-González, R.; Toledano, V.; Fernández-Velasco, M.; Vallejo-Cremades, M.T.; Esteban-Burgos, L.; de Diego, R.P.; Llamas-Matias, M.A.; García-Arumi, E.; Martí, R.; Boscá, L.; Andreu, A.L.; López-Sendón, J.L.; López-Collazo, E. "Mitochondrial DAMPs induce endotoxin tolerance in human monocytes: an observation in patients with myocardial infarction.". PLoS ONE. 9(5): e95073. (2014). (PMID: 24797663).
Gómez-Hurtado, N.; Fernández-Velasco, M.; Fernández-Alfonso, M.S.; Boscá, L.; Delgado, C. "Prolonged leptin treatment increases transient outward K⁺ current via upregulation of Kv4.2 and Kv4.3 channel subunits in adult rat ventricular myocytes.". Pflugers Arch.. 466(5): 903-914. (2014). (PMID: 24046152).
Fernández-Velasco, M.; González-Ramos, S.; Boscá, L. "Involvement of monocytes/macrophages as key factors in the development and progression of cardiovascular diseases.". Biochem. J.. 458(2): 187-193. (2014). (PMID: 24524191).
Ruiz-Hurtado, G.; Gómez-Hurtado, N.; Fernández-Velasco, M.; Calderón, E.; Smani, T.; Ordoñez, A.; Cachofeiro, V.; Boscá, L.; Díez, J.; Gómez, A.M.; Delgado, C. "Cardiotrophin-1 induces sarcoplasmic reticulum Ca(2+) leak and arrhythmogenesis in adult rat ventricular myocytes.". Cardiovasc. Res.. 96(1): 81-89. (2012). (PMID: 22787135).
García-Hoz, C.; Sánchez-Fernández, G.; García-Escudero, R.; Fernández-Velasco, M.; Palacios-García, J.; Ruiz-Meana, M.; Díaz-Meco, M.T.; Leitges, M.; Moscat, J.; García-Dorado, D.; Boscá, L.; Mayor, F.; Ribas, C. "Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts.". J. Biol. Chem.. 287(10): 7792-7802. (2012). (PMID: 22232556).
Cuadrado, I.; Fernández-Velasco, M.; Boscá, L.; de Las Heras, B. "Labdane diterpenes protect against anoxia/reperfusion injury in cardiomyocytes: involvement of AKT activation.". Cell Death Dis. 2(): e229. (2011). (PMID: 22071634).
Fernández-Velasco, M.; Ruiz-Hurtado, G.; Rueda, A.; Neco, P.; Mercado-Morales, M.; Delgado, C.; Napolitano, C.; Priori, S.G.; Richard, S.; Gómez, A.M.; Benitah, J.P. "RyRCa2+ leak limits cardiac Ca2+ window current overcoming the tonic effect of calmodulinin mice.". PLoS ONE. 6(6): e20863. (2011). (PMID: 21673970).
Smani, T.; Calderón-Sanchez, E.; Gómez-Hurtado, N.; Fernández-Velasco, M.; Cachofeiro, V.; Lahera, V.; Ordoñez, A.; Delgado, C. "Mechanisms underlying the activation of L-type calcium channels by urocortin in rat ventricular myocytes.". Cardiovasc. Res.. 87(3): 459-466. (2010). (PMID: 20189952).
Ruiz-Hurtado, G.; Fernández-Velasco, M.; Mourelle, M.; Delgado, C. "LA419, a novel nitric oxide donor, prevents pathological cardiac remodeling in pressure-overloaded rats via endothelial nitric oxide synthase pathway regulation.". Hypertension. 50(6): 1049-1056. (2007). (PMID: 17984372).
Fernández-Velasco, M.; Ruiz-Hurtado, G.; Hurtado, O.; Moro, M.A.; Delgado, C. "TNF-alpha downregulates transient outward potassium current in rat ventricular myocytes through iNOS overexpression and oxidant species generation.". Am. J. Physiol. Heart Circ. Physiol.. 293(1): H238-45. (2007). (PMID: 17337591).
Fernández-Velasco, M.; Ruiz-Hurtado, G.; Delgado, C. "I K1 and I f in ventricular myocytes isolated from control and hypertrophied rat hearts.". Pflugers Arch.. 452(2): 146-154. (2006). (PMID: 16395601).
Fernández-Velasco, M.; Goren, N.; Benito, G.; Blanco-Rivero, J.; Boscá, L.; Delgado, C. "Regional distribution of hyperpolarization-activated current (If) and hyperpolarization-activated cyclic nucleotide-gated channel mRNA expression in ventricular cells from control and hypertrophied rat hearts.". J. Physiol. (Lond.). 553(Pt 2): 395-405. (2003). (PMID: 14514868).
Heredia, M.P.; Fernández-Velasco, M.; Benito, G.; Delgado, C. "Neuropeptide Y increases 4-aminopyridine-sensitive transient outward potassium current in rat ventricular myocytes.". Br. J. Pharmacol.. 135(7): 1701-1706. (2002). (PMID: 11934810).
Instituto de Investigaciones Biomédicas "Alberto Sols"
C/Arturo Duperier 4. 28029 Madrid. (Spain)
Tel +(34) 91 585 4400 // Fax +(34) 91 558 4401 Email:Info