Martinez-deMena, R.; Calvo, R.M.; Garcia, L.; Obregon, M.J. "Effect of glucocorticoids on the activity, expression and proximal promoter of type II deiodinase in rat brown adipocytes.". Mol. Cell. Endocrinol.. 428(): 58-67. (2016). (PMID: 26994513).
Martinez-deMena, R.; Anedda, A.; Cadenas, S.; Obregon, M.J. "TSH effects on thermogenesis in rat brown adipocytes.". Mol. Cell. Endocrinol.. 404(): 151-158. (2015). (PMID: 25662278).
Lavado-Autric, R.; Calvo, R.M.; de Mena, R.M.; de Escobar, G.M.; Obregon, M.J. "Deiodinase activities in thyroids and tissues of iodine-deficient female rats.". Endocrinology. 154(1): 529-536. (2013). (PMID: 23142811).
Garcia, B.; Martinez-de-Mena, R.; Obregon, M.J. "Arachidonic acid stimulates DNA synthesis in brown preadipocytes through the activation of protein kinase C and MAPK.". Biochim. Biophys. Acta. 1821(10): 1309-1315. (2012). (PMID: 22766489).
Hernandez, A.; de Mena, R.M.; Martin, E.; Obregon, M.J. "Differences in the response of UCP1 mRNA to hormonal stimulation between rat and mouse primary cultures of brown adipocytes.". Cell. Physiol. Biochem.. 28(5): 969-980. (2011). (PMID: 22178948).
Martinez de Mena, R.; Scanlan, T.S.; Obregon, M.J. "The T3 receptor beta1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes.". Endocrinology. 151(10): 5074-5083. (2010). (PMID: 20719854).
Barrantes, I.d.e.l. .B.; Montero-Pedrazuela, A.; Guadaño-Ferraz, A.; Obregon, M.J.; Martinez de Mena, R.; Gailus-Durner, V.; Fuchs, H.; Franz, T.J.; Kalaydjiev, S.; Klempt, M.; Hölter, S.; Rathkolb, B.; Reinhard, C.; Morreale de Escobar, G.; Bernal, J.; Busch, D.H.; Wurst, W.; Wolf, E.; Schulz, H.; Shtrom, S.; Greiner, E.; Hrabé de Angelis, M.; Westphal, H.; Niehrs, C. "Generation and characterization of dickkopf3 mutant mice.". Mol. Cell. Biol.. 26(6): 2317-2326. (2006). (PMID: 16508007).
Martinez-deMena, R.; Obregón, M.J. "Insulin increases the adrenergic stimulation of 5' deiodinase activity and mRNA expression in rat brown adipocytes; role of MAPK and PI3K.". J Mol Endocrinol. 34(1): 139-151. (2005). (PMID: 15691884).
Alvarez, L.; Hernández, S.; Martinez-de-Mena, R.; Kolliker-Frers, R.; Obregón, M.J.; Kleiman de Pisarev, D.L. "The role of type I and type II 5' deiodinases on hexachlorobenzene-induced alteration of the hormonal thyroid status.". Toxicology. 207(3): 349-362. (2005). (PMID: 15664263).
Kester, M.H.; Martinez de Mena, R.; Obregon, M.J.; Marinkovic, D.; Howatson, A.; Visser, T.J.; Hume, R.; Morreale de Escobar, G. "Iodothyronine levels in the human developing brain: major regulatory roles of iodothyronine deiodinases in different areas.". J. Clin. Endocrinol. Metab.. 89(7): 3117-3128. (2004). (PMID: 15240580).
Martinez-deMena, R.; Hernández, A.; Obregón, M.J. "Triiodothyronine is required for the stimulation of type II 5'-deiodinase mRNA in rat brown adipocytes.". Am. J. Physiol. Endocrinol. Metab.. 282(5): E1119-27. (2002). (PMID: 11934678).
Instituto de Investigaciones Biomédicas "Alberto Sols"
C/Arturo Duperier 4. 28029 Madrid. (Spain)
Tel +(34) 91 585 4400 // Fax +(34) 91 558 4401 Email:Info