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PUBLICACIONES

 

 

spacerTrabajos Publicados por Lisardo Boscá Gomar
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  1. Sánchez-García, S.; Jaén, R.I.; Lozano-Rodríguez, R.; Avendaño-Ortiz, J.; Pascual-Iglesias, A.; Hurtado-Navarro, L.; López-Collazo, E.; Boscá, L.; Prieto, P. "Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers.". Front Immunol. 15(): 1509188. (2024). (PMID: 39916956).
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  2. Sánchez-García, S.; Povo-Retana, A.; Marin, S.; Madurga, S.; Fariñas, M.; Aleixandre, N.; Castrillo, A.; de la Rosa, J.V.; Alvarez-Lucena, C.; Landauro-Vera, R.; Prieto, P.; Cascante, M.; Boscá, L. "Immunometabolic Effect of Nitric Oxide on Human Macrophages Challenged With the SARS-CoV2-Induced Cytokine Storm. A Fluxomic Approach.". Adv Healthc Mater. (): e2401688. (2024). (PMID: 39502019).
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  3. González-Lafuente, L.; Mercado-García, E.; Vázquez-Sánchez, S.; González-Moreno, D.; Boscá, L.; Fernández-Velasco, M.; Segura, J.; Kuro-O, M.; Ruilope, L.M.; Liaño, F.; Ruiz-Hurtado, G. "Interleukin-6 as a prognostic marker in acute kidney injury and its klotho-dependent regulation.". Nefrologia (Engl Ed). 44(6): 818-829. (2024). (PMID: 39616092).
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  4. Sánchez-García, S.; Castrillo, A.; Boscá, L.; Prieto, P. "Potential Beneficial Role of Nitric Oxide in SARS-CoV-2 Infection: Beyond Spike-Binding Inhibition.". Antioxidants (Basel). 13(11): . (2024). (PMID: 39594443).
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  5. Chakraborty, A.; Sreenivasmurthy, S.G.; Miller, W.; Huai, W.; Biswas, T.; Mandal, S.M.; Boscá, L.; Krishnan, B.; Ghosh, G.; Hazra, T. "Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's disease.". Proc Natl Acad Sci U S A. 121(39): e2406308121. (2024). (PMID: 39298485).
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  6. Hernández-Hernández, I.; De La Rosa, J.V.; Martín-Rodríguez, P.; Díaz-Sarmiento, M.; Recio, C.; Guerra, B.; Fernández-Pérez, L.; León, T.E.; Torres, R.; Font-Díaz, J.; Roig, A.; de Mora, F.; Boscá, L.; Díaz, M.; Valledor, A.F.; Castrillo, A.; Tabraue, C. "Endogenous LXR signaling controls pulmonary surfactant homeostasis and prevents lung inflammation.". Cell Mol Life Sci. 81(1): 287. (2024). (PMID: 38970705).
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  7. Brea, R.; Casanova, N.; Alvarez-Lucena, C.; Fuertes-Agudo, M.; Luque-Tevar, M.; Cucarella, C.; Capitani, M.C.; Marinochi, M.V.; Fusini, M.E.; Lahoz, A.; Nogueroles, M.L.; Fraile, J.; Ronco, M.T.; Boscá, L.; González-Rodríguez, Á.; García-Monzón, C.; Martín-Sanz, P.; Casado, M.; Francés, D.E. "Beneficial effects of hepatic cyclooxygenase-2 expression against cholestatic injury after common bile duct ligation in mice.". Liver Int. (): . (2024). (PMID: 38847511).
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  8. Tébar, D.; Jurado-Román, A.; Jiménez-Valero, S.; Galeote, G.; Gonzálvez, A.; Rivero, B.; García, A.; Añón Elizalde, J.M.; Lorenzo, A.; Fernández Capitán, C.; Torres, R.; Soto, C.; Alcolea, S.; Rosillo, S.; Caro Codón, J.; Arbas, E.; Tejera, F.; Plaza, I.; Boscá, L.; Moreno, R. "Percutaneous pulmonary thrombectomy with aspiration catheters in patients with high-risk pulmonary embolism and absolute contraindication to systemic thrombolysis.". Cardiovasc Revasc Med. (): . (2024). (PMID: 38960828).
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  9. Tébar, D.; Carrillo, X.; García Del Blanco, B.; Gómez-Hospital, J.A.; Nombela, L.; Molina, E.; Galeote, G.; Vilalta, V.; Serra-García, V.; Carol, G.M.; Jiménez-Valero, S.; Fernandez-Nofrerias, E.; Calabuig-Goena, Á.; Jurado-Román, A.; Sánchez-Recalde, Á.; Velasco, M.F.; Bosca, L.; Moreno, R. "Experience with the ACURATE neo and neo2 transcatheter aortic valves in Spain. The PRECISA (PRospective Evaluation Complementing Investigation with ACURATE devices) registry.". Catheter Cardiovasc Interv. 103(6): 1015-1022. (2024). (PMID: 38577931).
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  10. González-Nicolás, M.Á.; González-Guerrero, C.; Goicoechea, M.; Boscá, L.; Valiño-Rivas, L.; Lázaro, A. "Biomarkers in Contrast-Induced Acute Kidney Injury: Towards A New Perspective.". Int J Mol Sci. 25(6): . (2024). (PMID: 38542410).
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  11. Vladimir de la Rosa, J.; Tabraue, C.; Huang, Z.; Orizaola, M.C.; Martin-Rodríguez, P.; Steffensen, K.R.; Zapata, J.M.; Boscá, L.; Tontonoz, P.; Alemany, S.; Treuter, E.; Castrillo, A. "Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses.". Adv Sci (Weinh). (): e2307201. (2024). (PMID: 38549193).
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  12. Apaza, C.J.; Días, M.; García Tejedor, A.; Boscá, L.; Laparra Llopis, J.M. "Contribution of Nucleotide-Binding Oligomerization Domain-like (NOD) Receptors to the Immune and Metabolic Health.". Biomedicines. 12(2): . (2024). (PMID: 38397943).
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  13. Povo-Retana, A.; Landauro-Vera, R.; Alvarez-Lucena, C.; Cascante, M.; Boscá, L. "Trabectedin and Lurbinectedin Modulate the Interplay between Cells in the Tumour Microenvironment-Progresses in Their Use in Combined Cancer Therapy.". Molecules. 29(2): . (2024). (PMID: 38257245).
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  14. Cerrato, G.; Alvarez-Lucena, C.; Sauvat, A.; Hu, Y.; Forveille, S.; Chen, G.; Durand, S.; Aprahamian, F.; Leduc, M.; Motiño, O.; Boscá, L.; Xu, Q.; Kepp, O.; Kroemer, G. "3,4-dimethoxychalcone induces autophagy and reduces neointimal hyperplasia and aortic lesions in mouse models of atherosclerosis.". Cell Death Dis. 14(11): 758. (2023). (PMID: 37989732).
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  15. Sánchez-García, S.; Jaén, R.I.; Fernández-Velasco, M.; Delgado, C.; Boscá, L.; Prieto, P. "Lipoxin-mediated signaling: ALX/FPR2 interaction and beyond.". Pharmacol Res. 197(): 106982. (2023). (PMID: 37925045).
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  16. Chakraborty, A.; Miller, W.; Huai, W.; Biswas, T.; Mohan Mandal, S.; Bosca, L.; Ghosh, G.; Hazra, T. "A glycolytic metabolite restores DNA repair activity of polynucleotide kinase 3'-phosphatase in polyglutamine (PolyQ) diseases.". bioRxiv. (): . (2023). (PMID: 37961108).
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  17. Povo-Retana, A.; Fariñas, M.; Landauro-Vera, R.; Mojena, M.; Alvarez-Lucena, C.; Fernández-Moreno, M.A.; Castrillo, A.; de la Rosa Medina, J.V.; Sánchez-García, S.; Foguet, C.; Mas, F.; Marin, S.; Cascante, M.; Boscá, L. "Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity.". Front Immunol. 14(): 1211068. (2023). (PMID: 37675104).
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  18. Garcia-Martinez, I.; Alen, R.; Pereira, L.; Povo-Retana, A.; Astudillo, A.M.; Hitos, A.B.; Gomez-Hurtado, I.; Lopez-Collazo, E.; Boscá, L.; Francés, R.; Lizasoain, I.; Moro, M.Á.; Balsinde, J.; Izquierdo, M.; Valverde, Á.M. "Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance.". JHEP Rep. 5(8): 100756. (2023). (PMID: 37360906).
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  19. Povo-Retana, A.; Landauro-Vera, R.; Fariñas, M.; Sánchez-García, S.; Alvarez-Lucena, C.; Marin, S.; Cascante, M.; Boscá, L. "Defining the metabolic signatures associated with human macrophage polarisation.". Biochem Soc Trans. (): . (2023). (PMID: 37449892).
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  20. Hamdy, N.M.; Bosca, L.; Singh, S.M.; Reddy Bonam, S.; Kiss, I.; Kumar, D.P.; Banerjee, A. "Editorial: Women in gastrointestinal cancers, volume II: 2022.". Front Oncol. 13(): 1192814. (2023). (PMID: 37265801).
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  21. Povo-Retana, A.; Sánchez-García, S.; Alvarez-Lucena, C.; Landauro-Vera, R.; Prieto, P.; Delgado, C.; Martín-Sanz, P.; Boscá, L. "Crosstalk between P2Y receptors and cyclooxygenase activity in inflammation and tissue repair.". Purinergic Signal. (): . (2023). (PMID: 37052777).
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  22. Peraza, D.A.; Povo-Retana, A.; Mojena, M.; García-Redondo, A.B.; Avilés, P.; Boscá, L.; Valenzuela, C. "Trabectedin modulates macrophage polarization in the tumor-microenvironment. Role of KV1.3 and KV1.5 channels.". Biomed Pharmacother. 161(): 114548. (2023). (PMID: 36940615).
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  23. Paz-García, M.; Povo-Retana, A.; Jaén, R.I.; Prieto, P.; Peraza, D.A.; Zaragoza, C.; Hernandez-Jimenez, M.; Pineiro, D.; Regadera, J.; García-Bermejo, M.L.; Rodríguez-Serrano, E.M.; Sánchez-García, S.; Moro, M.A.; Lizasoaín, I.; Delgado, C.; Valenzuela, C.; Boscá, L. "Beneficial effect of TLR4 blockade by a specific aptamer antagonist after acute myocardial infarction.". Biomed Pharmacother. 158(): 114214. (2023). (PMID: 36916435).
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  24. Amich, I.; Anguita, E.; Escribano-Serrat, S.; Alvarez, C.; Rodríguez-Muñoz, D.; García, V.; Bello, R.; Peña-Pedrosa, J.A.; Martínez-Micaelo, N.; Amigó, N.; Ortiz, P.; Torrejón, M.J.; Boscá, L.; Martín-Sánchez, J.; Aranda, A.; Alemany, S. "Free triiodothyronine levels and age influences the metabolic profile and COVID-19 severity parameters in euthyroid and levothyroxine-treated patients.". Front Endocrinol (Lausanne). 13(): 1025032. (2022). (PMID: 36440226).
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  25. Alvarez, M.S.; Núñez, E.; Fuertes-Agudo, M.; Cucarella, C.; Fernandez-Velasco, M.; Boscá, L.; Vázquez, J.; Rossignol, R.; Martin-Sanz, P.; Casado, M. "Quantitative Proteomics Analysis Reveals That Cyclooxygenase-2 Modulates Mitochondrial Respiratory Chain Complex IV in Cardiomyocytes.". Int J Mol Sci. 23(21): . (2022). (PMID: 36362254).
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  26. Fuertes-Agudo, M.; Luque-Tévar, M.; Cucarella, C.; Brea, R.; Boscá, L.; Quintana-Cabrera, R.; Martín-Sanz, P.; Casado, M. "COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury.". Antioxidants (Basel). 11(9): . (2022). (PMID: 36139798).
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  27. Jaén, R.I.; Povo-Retana, A.; Rosales-Mendoza, C.; Capillas-Herrero, P.; Sánchez-García, S.; Martín-Sanz, P.; Mojena, M.; Prieto, P.; Boscá, L. "Functional Crosstalk between PCSK9 Internalization and Pro-Inflammatory Activation in Human Macrophages: Role of Reactive Oxygen Species Release.". Int J Mol Sci. 23(16): . (2022). (PMID: 36012389).
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  28. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Castrillo, A.; Boscá, L. "Unraveling the interplay between iron homeostasis, ferroptosis and extramedullary hematopoiesis.". Pharmacol Res. 183(): 106386. (2022). (PMID: 35933006).
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  29. Fernández-García, V.; González-Ramos, S.; Avendaño-Ortiz, J.; Martín-Sanz, P.; Gómez-Coronado, D.; Delgado, C.; Castrillo, A.; Boscá, L. "High-fat diet activates splenic NOD1 and enhances neutrophil recruitment and neutrophil extracellular traps release in the spleen of ApoE-deficient mice.". Cell Mol Life Sci. 79(8): 396. (2022). (PMID: 35789437).
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  30. Val-Blasco, A.; Prieto, P.; Jaén, R.I.; Gil-Fernández, M.; Pajares, M.; Domenech, N.; Terrón, V.; Tamayo, M.; Jorge, I.; Vázquez, J.; Bueno-Sen, A.; Vallejo-Cremades, M.T.; Pombo-Otero, J.; Sanchez-García, S.; Ruiz-Hurtado, G.; Gómez, A.M.; Zaragoza, C.; Crespo-Leiro, M.G.; López-Collazo, E.; Cuadrado, A.; Delgado, C.; Boscá, L.; Fernández-Velasco, M. "Specialized Proresolving Mediators Protect Against Experimental Autoimmune Myocarditis by Modulating Ca2+ Handling and NRF2 Activation.". JACC Basic Transl Sci. 7(6): 544-560. (2022). (PMID: 35818504).
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  31. Tamayo, M.; Martín-Nunes, L.; Piedras, M.J.; Martin-Calvo, M.; Martí-Morente, D.; Gil-Fernández, M.; Gómez-Hurtado, N.; Moro, M.Á.; Bosca, L.; Fernández-Velasco, M.; Delgado, C. "The Aryl Hydrocarbon Receptor Ligand FICZ Improves Left Ventricular Remodeling and Cardiac Function at the Onset of Pressure Overload-Induced Heart Failure in Mice.". Int J Mol Sci. 23(10): . (2022). (PMID: 35628213).
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  32. Fernández-García, V.; González-Ramos, S.; Avendaño-Ortiz, J.; Martín-Sanz, P.; Delgado, C.; Castrillo, A.; Boscá, L. "NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions.". Biomed Pharmacother. 148(): 112769. (2022). (PMID: 35247718).
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  33. Kovacic, J.C.; Boscá, L. "Immuno-Modulation to Treat Common Cardiovascular Diseases: Moving From Sledgehammer to Precision Therapeutics.". J Am Coll Cardiol. 79(7): 648-650. (2022). (PMID: 35177193).
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  34. Povo-Retana, A.; Mojena, M.; Boscá, A.; Pedrós, J.; Peraza, D.A.; Valenzuela, C.; Laparra, J.M.; Calle, F.; Boscá, L. "Graphene Particles Interfere with Pro-Inflammatory Polarization of Human Macrophages: Functional and Electrophysiological Evidence.". Adv Biol (Weinh). (): e2100882. (2021). (PMID: 34590442).
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  35. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Portillo, F.G.; Laparra, J.M.; Boscá, L. "NOD1 in the interplay between microbiota and gastrointestinal immune adaptations.". Pharmacol Res. (): 105775. (2021). (PMID: 34273489).
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  36. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Laparra, J.M.; Boscá, L. "Beyond classic concepts in thyroid homeostasis: immune system and microbiota.". Mol Cell Endocrinol. (): 111333. (2021). (PMID: 34048865).
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  37. Ramírez, C.M.; Torrecilla-Parra, M.; Pardo-Marqués, V.; de-Frutos, M.F.; Pérez-García, A.; Tabraue, C.; de la Rosa, J.V.; Martín-Rodriguez, P.; Díaz-Sarmiento, M.; Nuñez, U.; Orizaola, M.C.; Través, P.G.; Camps, M.; Boscá, L.; Castrillo, A. "Crosstalk Between LXR and Caveolin-1 Signaling Supports Cholesterol Efflux and Anti-Inflammatory Pathways in Macrophages.". Front Endocrinol (Lausanne). 12(): 635923. (2021). (PMID: 34122329).
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  38. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Laparra, J.M.; Boscá, L. "NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health.". Biomedicines. 9(5): . (2021). (PMID: 34066406).
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  39. Jaén, R.I.; Sánchez-García, S.; Fernández-Velasco, M.; Boscá, L.; Prieto, P. "Resolution-Based Therapies: The Potential of Lipoxins to Treat Human Diseases.". Front Immunol. 12(): 658840. (2021). (PMID: 33968061).
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  40. Brea, R.; Valdecantos, P.; Rada, P.; Alen, R.; García-Monzón, C.; Boscá, L.; Fuertes-Agudo, M.; Casado, M.; Martín-Sanz, P.; Valverde, Á.M. "Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress.". Aging (Albany NY). 13(6): 7800-7827. (2021). (PMID: 33780353).
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  41. Fernández-García, V.; Boscá, L. "Use of 11C-acetate PET imaging in the evaluation of advanced atherogenic lesions.". J Nucl Cardiol. (): . (2021). (PMID: 33665731).
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  42. Fernández-García, V.; González-Ramos, S.; Martín-Sanz, P.; Castrillo, A.; Boscá, L. "Contribution of Extramedullary Hematopoiesis to Atherosclerosis. The Spleen as a Neglected Hub of Inflammatory Cells.". Front Immunol. 11(): 586527. (2020). (PMID: 33193412).
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  43. Povo-Retana, A.; Mojena, M.; Stremtan, A.B.; Fernández-García, V.B.; Gómez-Sáez, A.; Nuevo-Tapioles, C.; Molina-Guijarro, J.M.; Avendaño-Ortiz, J.; Cuezva, J.M.; López-Collazo, E.; Martínez-Leal, J.F.; Boscá, L. "Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights.". Cancers (Basel). 12(10): . (2020). (PMID: 33092171).
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  44. González-Ramos, S.; Fernández-García, V.; Recalde, M.; Rodríguez, C.; Martínez-González, J.; Andrés, V.; Martín-Sanz, P.; Boscá, L. "Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis †.". Cells. 9(9): . (2020). (PMID: 32927803).
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  45. Pajares, M.; I Rojo, A.; Manda, G.; Boscá, L.; Cuadrado, A. "Inflammation in Parkinson's Disease: Mechanisms and Therapeutic Implications.". Cells. 9(7): . (2020). (PMID: 32674367).
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  46. Jaén, R.I.; Val-Blasco, A.; Prieto, P.; Gil-Fernández, M.; Smani, T.; López-Sendón, J.L.; Delgado, C.; Boscá, L.; Fernández-Velasco, M. "Innate Immune Receptors, Key Actors in Cardiovascular Diseases.". JACC Basic Transl Sci. 5(7): 735-749. (2020). (PMID: 32760860).
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  47. González-Ramos, S.; Paz-García, M.; Fernández-García, V.; Portune, K.J.; Acosta-Medina, E.F.; Sanz, Y.; Castrillo, A.; Martín-Sanz, P.; Obregon, M.J.; Boscá, L. "NOD1 deficiency promotes an imbalance of thyroid hormones and microbiota homeostasis in mice fed high fat diet.". Sci Rep. 10(1): 12317. (2020). (PMID: 32704052).
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  48. Jaén, R.I.; Fernández-Velasco, M.; Terrón, V.; Sánchez-García, S.; Zaragoza, C.; Canales-Bueno, N.; Val-Blasco, A.; Vallejo-Cremades, M.T.; Boscá, L.; Prieto, P. "BML-111 treatment prevents cardiac apoptosis and oxidative stress in a mouse model of autoimmune myocarditis.". FASEB J.. (): . (2020). (PMID: 32543747).
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  49. Aguirre, L.A.; Montalbán-Hernández, K.; Avendaño-Ortiz, J.; Marín, E.; Lozano, R.; Toledano, V.; Sánchez-Maroto, L.; Terrón, V.; Valentín, J.; Pulido, E.; Casalvilla, J.C.; Rubio, C.; Diekhorst, L.; Laso-García, F.; Del Fresno, C.; Collazo-Lorduy, A.; Jiménez-Munarriz, B.; Gómez-Campelo, P.; Llanos-González, E.; Fernández-Velasco, M.; Rodríguez-Antolín, C.; Pérez de Diego, R.; Cantero-Cid, R.; Hernádez-Jimenez, E.; Álvarez, E.; Rosas, R.; Dies López-Ayllón, B.; de Castro, J.; Wculek, S.K.; Cubillos-Zapata, C.; Ibáñez de Cáceres, I.; Díaz-Agero, P.; Gutiérrez Fernández, M.; Paz de Miguel, M.; Sancho, D.; Schulte, L.; Perona, R.; Belda-Iniesta, C.; Boscá, L.; López-Collazo, E. "Tumor stem cells fuse with monocytes to form highly invasive tumor-hybrid cells.". Oncoimmunology. 9(1): 1773204. (2020). (PMID: 32923132).
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  50. Vila-Bedmar, R.; Cruces-Sande, M.; Arcones, A.C.; Willemen, H.L.D.M.; Prieto, P.; Moreno-Indias, I.; Díaz-Rodríguez, D.; Francisco, S.; Jaén, R.I.; Gutiérrez-Repiso, C.; Heijnen, C.J.; Boscá, L.; Fresno, M.; Kavelaars, A.; Mayor, F.; Murga, C. "GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity.". Cell. Mol. Life Sci.. (): . (2020). (PMID: 31927610).
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  51. Rossello, X.; Rodriguez-Sinovas, A.; Vilahur, G.; Crisóstomo, V.; Jorge, I.; Zaragoza, C.; Zamorano, J.L.; Bermejo, J.; Ordoñez, A.; Boscá, L.; Vázquez, J.; Badimón, L.; Sánchez-Margallo, F.M.; Fernández-Avilés, F.; Garcia-Dorado, D.; Ibanez, B. "CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform): A multicenter preclinical network for testing reproducibility in cardiovascular interventions.". Sci Rep. 9(1): 20290. (2019). (PMID: 31889088).
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  52. Haider, N.; Boscá, L.; Zandbergen, H.R.; Kovacic, J.C.; Narula, N.; González-Ramos, S.; Fernandez-Velasco, M.; Agrawal, S.; Paz-García, M.; Gupta, S.; DeLeon-Pennell, K.; Fuster, V.; Ibañez, B.; Narula, J. "Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction.". J. Am. Coll. Cardiol.. 74(25): 3124-3135. (2019). (PMID: 31856969).
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  53. Virág, L.; Jaén, R.I.; Regdon, Z.; Boscá, L.; Prieto, P. "Self-defense of macrophages against oxidative injury: Fighting for their own survival.". Redox Biol. 26(): 101261. (2019). (PMID: 31279985).
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  54. Motiño, O.; Francés, D.E.; Casanova, N.; Fuertes-Agudo, M.; Cucarella, C.; Flores, J.M.; Vallejo-Cremades, M.T.; Olmedilla, L.; Pérez Peña, J.; Bañares, R.; Boscá, L.; Casado, M.; Martín-Sanz, P. "Protective Role of Hepatocyte Cyclooxygenase-2 Expression Against Liver Ischemia-Reperfusion Injury in Mice.". Hepatology. 70(2): 650-665. (2019). (PMID: 30155948).
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  55. Tabraue, C.; Lara, P.C.; De Mirecki-Garrido, M.; De La Rosa, J.V.; López-Blanco, F.; Fernández-Pérez, L.; Boscá, L.; Castrillo, A. "LXR Signaling Regulates Macrophage Survival and Inflammation in Response to Ionizing Radiation.". Int. J. Radiat. Oncol. Biol. Phys.. 104(4): 913-923. (2019). (PMID: 30922944).
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  56. Martínez-Frailes, C.; Di Lauro, C.; Bianchi, C.; de Diego-García, L.; Sebastián-Serrano, Á.; Boscá, L.; Díaz-Hernández, M. "Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality.". Front Cell Neurosci. 13(): 143. (2019). (PMID: 31031598).
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  57. González-Ramos, S.; Paz-García, M.; Rius, C.; Del Monte-Monge, A.; Rodríguez, C.; Fernández-García, V.; Andrés, V.; Martínez-González, J.; Lasunción, M.A.; Martín-Sanz, P.; Soehnlein, O.; Boscá, L. "Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1.". FASEB J.. 33(3): 3912-3921. (2019). (PMID: 30496704).
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  58. Ramón-Vázquez, A.; de la Rosa, J.V.; Tabraue, C.; Lopez, F.; Díaz-Chico, B.N.; Bosca, L.; Tontonoz, P.; Alemany, S.; Castrillo, A. "Common and Differential Transcriptional Actions of Nuclear Receptors LXRα and LXRβ in macrophages.". Mol. Cell. Biol.. (): . (2019). (PMID: 30602495).
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  59. Prieto, P.; Jaén, R.I.; Calle, D.; Gómez-Serrano, M.; Núñez, E.; Fernández-Velasco, M.; Martín-Sanz, P.; Alonso, S.; Vázquez, J.; Cerdán, S.; Peinado, M.Á.; Boscá, L. "Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort.". World J. Gastroenterol.. 25(4): 433-446. (2019). (PMID: 30700940).
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  69. Val-Blasco, A.; Prieto, P.; Gonzalez-Ramos, S.; Benito, G.; Vallejo-Cremades, M.T.; Pacheco, I.; González-Peramato, P.; Agra, N.; Terrón, V.; Delgado, C.; Martín-Sanz, P.; Boscá, L.; Fernández-Velasco, M. "NOD1 activation in cardiac fibroblasts induces myocardial fibrosis in a murine model of type 2 diabetes.". Biochem. J.. 474(3): 399-410. (2017). (PMID: 27803247).
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  83. Delgado, C.; Ruiz-Hurtado, G.; Gómez-Hurtado, N.; González-Ramos, S.; Rueda, A.; Benito, G.; Prieto, P.; Zaragoza, C.; Delicado, E.G.; Pérez-Sen, R.; Miras-Portugal, M.T.; Núñez, G.; Boscá, L.; Fernández-Velasco, M. "NOD1, A new player in cardiac function and calcium handling.". Cardiovasc. Res.. (): . (2015). (PMID: 25824149).
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    CONCLUSION
    Our data provide the first evidence that NOD1 activation induces cardiac dysfunction associated with excitation-contraction coupling-impairment through NF-κB activation, and uncover a new proinflammatory player in the regulation of cardiovascular function.

    ')" value="Abstract">

  84. Cuadrado-Berrocal, I.; Gómez-Gaviro, M.V.; Benito, Y.; Barrio, A.; Bermejo, J.; Fernández-Santos, M.E.; Sánchez, P.L.; Desco, M.; Fernández-Avilés, F.; Fernández-Velasco, M.; Boscá, L.; de Las Heras, B. "A labdane diterpene exerts ex vivo and in vivo cardioprotection against post-ischemic injury: involvement of AKT-dependent mechanisms.". Biochem. Pharmacol.. 93(4): 428-439. (2015). (PMID: 25557296).
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  112. Manarin, R.; Pascutti, M.F.; Ruffino, J.P.; De Las Heras, B.; Boscá, L.; Bottasso, O.; Revelli, S.; Serra, E. "Benznidazole blocks NF-kappaB activation but not AP-1 through inhibition of IKK.". Mol. Immunol.. 47(15): 2485-2491. (2010). (PMID: 20598748).
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  113. Camano, S.; Lazaro, A.; Moreno-Gordaliza, E.; Torres, A.M.; de Lucas, C.; Humanes, B.; Lazaro, J.A.; Milagros Gomez-Gomez, M.; Bosca, L.; Tejedor, A. "Cilastatin attenuates cisplatin-induced proximal tubular cell damage.". J. Pharmacol. Exp. Ther.. 334(2): 419-429. (2010). (PMID: 20435919).
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