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PUBLICACIONES

 

 

spacerTrabajos Publicados por Benilde Jiménez Cuenca
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  1. Acosta-Iborra, B.; Gil-Acero, A.I.; Sanz-Gómez, M.; Berrouayel, Y.; Puente-Santamaría, L.; Alieva, M.; Del Peso, L.; Jiménez, B. "Bhlhe40 Regulates Proliferation and Angiogenesis in Mouse Embryoid Bodies under Hypoxia.". Int J Mol Sci. 25(14): . (2024). (PMID: 39062912).
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  2. Maeso-Alonso, L.; Alonso-Olivares, H.; Martínez-García, N.; López-Ferreras, L.; Villoch-Fernández, J.; Puente-Santamaría, L.; Colas-Algora, N.; Fernández-Corona, A.; Lorenzo-Marcos, M.E.; Jiménez, B.; Holmgren, L.; Wilhelm, M.; Millan, J.; Del Peso, L.; Claesson-Welsh, L.; Marques, M.M.; Marin, M.C. "p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin.". Cell Mol Life Sci. 79(10): 535. (2022). (PMID: 36180740).
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  3. Tiana, M.; Acosta-Iborra, B.; Hernández, R.; Galiana, C.; Fernández-Moreno, M.Á.; Jimenez, B.; Del Peso, L. "Metabolic labeling of RNA uncovers the contribution of transcription and decay rates on hypoxia-induced changes in RNA levels.". RNA. 26(8): 1006-1022. (2020). (PMID: 32295863).
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  4. Acosta-Iborra, B.; Tiana, M.; Maeso-Alonso, L.; Hernández-Sierra, R.; Herranz, G.; Santamaria, A.; Rey, C.; Luna, R.; Puente-Santamaria, L.; Marques, M.M.; Marin, M.C.; Del Peso, L.; Jiménez, B. "Hypoxia compensates cell cycle arrest with progenitor differentiation during angiogenesis.". FASEB J.. (): . (2020). (PMID: 32223018).
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  5. Tiana, M.; Acosta-Iborra, B.; Puente-Santamaría, L.; Hernansanz-Agustin, P.; Worsley-Hunt, R.; Masson, N.; García-Rio, F.; Mole, D.; Ratcliffe, P.; Wasserman, W.W.; Jimenez, B.; Del Peso, L. "The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia.". Nucleic Acids Res.. 46(1): 120-133. (2018). (PMID: 29059365).
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  6. Roche, O.; Deguiz, M.L.; Tiana, M.; Galiana-Ribote, C.; Martinez-Alcazar, D.; Rey-Serra, C.; Ranz-Ribeiro, B.; Casitas, R.; Galera, R.; Fernández-Navarro, I.; Sánchez-Cuéllar, S.; Bernard, V.; Ancochea, J.; Wasserman, W.W.; García-Rio, F.; Jimenez, B.; Del Peso, L. "Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia.". Nucleic Acids Res.. (): . (2016). (PMID: 27625398).
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  7. Nwani, N.G.; Deguiz, M.L.; Jimenez, B.; Vinokour, E.; Dubrovskyi, O.; Ugolkov, A.; Mazar, A.P.; Volpert, O.V. "Melanoma cells block PEDF production in fibroblasts to induce the tumor-promoting phenotype of cancer-associated fibroblasts.". Cancer Res.. (): . (2016). (PMID: 26921338).
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  8. Jiménez, B.; Tiana, M.; Del Peso, L. "lnc RNAs, hypoxia and metastasis.". Oncoscience. 2(10): 795-796. (2015). (PMID: 26682249).
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  9. Jiménez Cuenca, B.; Fernández-Barral, A.; Orgaz, J.L. "Microphthalmia-Associated Transcription Factor: A Central Regulator of Pigment Epithelium-Derived Factor Controlling Human Melanoma Progression.". Am. J. Pathol.. 185(7): 2069-2070. (2015). (PMID: 26093986).
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  10. Gómez-Maldonado, L.; Tiana, M.; Roche, O.; Prado-Cabrero, A.; Jensen, L.; Fernandez-Barral, A.; Guijarro-Muñoz, I.; Favaro, E.; Moreno-Bueno, G.; Sanz, L.; Aragones, J.; Harris, A.; Volpert, O.; Jimenez, B.; del Peso, L. "EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination.". Oncogene. 34(20): 2609-2620. (2015). (PMID: 25023702).
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  11. Aguilera, Ó.; González-Sancho, J.M.; Zazo, S.; Rincón, R.; Fernández, A.F.; Tapia, O.; Canals, F.; Morte, B.; Calvanese, V.; Orgaz, J.L.; Niell, N.; Aguilar, S.; Freije, J.M.; Graña, O.; Pisano, D.G.; Borrero, A.; Martínez-Useros, J.; Jiménez, B.; Fraga, M.F.; García-Foncillas, J.; López-Otín, C.; Lafarga, M.; Rojo, F.; Muñoz, A. "Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.". Oncotarget. 6(8): 5903-5917. (2015). (PMID: 25788273).
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  12. Bargiela-Iparraguirre, J.; Prado-Marchal, L.; Pajuelo-Lozano, N.; Jiménez, B.; Perona, R.; Sánchez-Pérez, I. "Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells.". Cell Cycle. 13(22): 3590-3601. (2014). (PMID: 25483095).
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  13. Menéndez, C.; Adrados, I.; Fernández-Barral, A.; Jiménez, B.; Flores, J.M.; Cañamero, M.; Fuchtbauer, E.M.; Beermann, F.; Palmero, I. "Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.". Pigment Cell Melanoma Res. 27(4): 674-677. (2014). (PMID: 24655373).
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  14. Fernández-Barral, A.; Orgaz, J.L.; Baquero, P.; Ali, Z.; Moreno, A.; Tiana, M.; Gómez, V.; Riveiro-Falkenbach, E.; Cañadas, C.; Zazo, S.; Bertolotto, C.; Davidson, I.; Rodríguez-Peralto, J.L.; Palmero, I.; Rojo, F.; Jensen, L.D.; del Peso, L.; Jiménez, B. "Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.". Neoplasia. 16(6): 529-542. (2014). (PMID: 25030625).
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  15. Baquero, P.; Sánchez-Hernández, I.; Jiménez-Mora, E.; Orgaz, J.L.; Jiménez, B.; Chiloeches, A. "(V600E)BRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism.". Cancer Lett.. 335(1): 232-241. (2013). (PMID: 23435375).
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  16. Bienes-Martínez, R.; Ordóñez, A.; Feijoo-Cuaresma, M.; Corral-Escariz, M.; Mateo, G.; Stenina, O.; Jiménez, B.; Calzada, M.J. "Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1.". Sci Rep. 2(): 788. (2012). (PMID: 23145312).
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  17. Fernández-Barral, A.; Orgaz, J.L.; Gomez, V.; del Peso, L.; Calzada, M.J.; Jiménez, B. "Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism.". PLoS ONE. 7(3): e32989. (2012). (PMID: 22457728).
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  18. Martinez-Poveda, B.; Gomez, V.; Alcaide-German, M.; Perruca, S.; Vazquez, S.; Alba, L.E.; Casanovas, O.; Garcia-Bermejo, M.L.; Peso, L.; Jimenez, B. "Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma.". Int. J. Oncol.. 39(3): 543-552. (2011). (PMID: 21667025).
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  19. Orgaz, J.L.; Benguria, A.; Sanchez-Martinez, C.; Ladhani, O.; Volpert, O.V.; Jimenez, B. "Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor.". Melanoma Res.. 21(4): 285-297. (2011). (PMID: 21673604).
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  20. Ladhani, O.; Sánchez-Martinez, C.; Orgaz, J.L.; Jimenez, B.; Volpert, O.V. "Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis.". Neoplasia. 13(7): 633-642. (2011). (PMID: 21750657).
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  21. Moncho-Amor, V.; Ibañez de Cáceres, I.; Bandres, E.; Martínez-Poveda, B.; Orgaz, J.L.; Sánchez-Pérez, I.; Zazo, S.; Rovira, A.; Albanell, J.; Jiménez, B.; Rojo, F.; Belda-Iniesta, C.; García-Foncillas, J.; Perona, R. "DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer.". Oncogene. 30(6): 668-678. (2011). (PMID: 20890299).
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  22. Moreno, A.; Palacios, A.; Orgaz, J.L.; Jimenez, B.; Blanco, F.J.; Palmero, I. "Functional impact of cancer-associated mutations in the tumor suppressor protein ING4.". Carcinogenesis. 31(11): 1932-1938. (2010). (PMID: 20705953).
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  23. Orgaz, J.L.; Ladhani, O.; Hoek, K.S.; Fernández-Barral, A.; Mihic, D.; Aguilera, O.; Seftor, E.A.; Bernad, A.; Rodríguez-Peralto, J.L.; Hendrix, M.J.; Volpert, O.V.; Jiménez, B. "'Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma'.". Oncogene. 28(47): 4147-4161. (2009). (PMID: 19767774).
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  24. Orgaz, J.L.; Martínez-Poveda, B.; Fernández-García, N.I.; Jiménez, B. "Following up tumour angiogenesis: from the basic laboratory to the clinic.". Clin Transl Oncol. 10(8): 468-477. (2008). (PMID: 18667377).
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  25. Pendás-Franco, N.; García, J.M.; Peña, C.; Valle, N.; Pálmer, H.G.; Heinäniemi, M.; Carlberg, C.; Jiménez, B.; Bonilla, F.; Muñoz, A.; González-Sancho, J.M. "DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.". Oncogene. 27(32): 4467-4477. (2008). (PMID: 18408752).
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  26. Fernandez-Garcia, N.I.; Volpert, O.V.; Jimenez, B. "Pigment epithelium-derived factor as a multifunctional antitumor factor.". J. Mol. Med.. 85(1): 15-22. (2007). (PMID: 17106733).
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  27. Fernandez-Garcia, N.I.; Palmer, H.G.; Garcia, M.; Gonzalez-Martin, A.; del Rio, M.; Barettino, D.; Volpert, O.; Muñoz, A.; Jimenez, B. "1alpha,25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells.". Oncogene. 24(43): 6533-6544. (2005). (PMID: 16007183).
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  28. Garcia, M.; Fernandez-Garcia, N.I.; Rivas, V.; Carretero, M.; Escamez, M.J.; Gonzalez-Martin, A.; Medrano, E.E.; Volpert, O.; Jorcano, J.L.; Jimenez, B.; Larcher, F.; Del Rio, M. "Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor.". Cancer Res.. 64(16): 5632-5642. (2004). (PMID: 15313901).
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  29. Jiménez Cuenca, B. "[Mechanism of inhibition of tumoral angiogenesis by thrombospondin-1].". Nefrologia. 23 Suppl 3(): 49-53. (2003). (PMID: 12901193).
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  30. Caelles, C.; Bruna, A.; Morales, M.; González-Sancho, J.M.; González, M.V.; Jiménez, B.; Muñoz, A. "Glucocorticoid receptor antagonism of AP-1 activity by inhibition of MAPK family.". Ernst Schering Res. Found. Workshop. (40): 131-152. (2002). (PMID: 12355714).
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  31. Reiher, F.K.; Volpert, O.V.; Jimenez, B.; Crawford, S.E.; Dinney, C.P.; Henkin, J.; Haviv, F.; Bouck, N.P.; Campbell, S.C. "Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics.". Int. J. Cancer. 98(5): 682-689. (2002). (PMID: 11920636).
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  32. Jiménez, B.; Volpert, O.V. "Mechanistic insights on the inhibition of tumor angiogenesis.". J. Mol. Med.. 78(12): 663-672. (2001). (PMID: 11434719).
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  33. Jiménez, B.; Volpert, O.V.; Reiher, F.; Chang, L.; Muñoz, A.; Karin, M.; Bouck, N. "c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1.". Oncogene. 20(26): 3443-3448. (2001). (PMID: 11423995).
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  34. González, M.V.; Jiménez, B.; Berciano, M.T.; González-Sancho, J.M.; Caelles, C.; Lafarga, M.; Muñoz, A. "Glucocorticoids antagonize AP-1 by inhibiting the Activation/phosphorylation of JNK without affecting its subcellular distribution.". J. Cell Biol.. 150(5): 1199-1208. (2000). (PMID: 10974006).
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  35. Jiménez, B.; Volpert, O.V.; Crawford, S.E.; Febbraio, M.; Silverstein, R.L.; Bouck, N. "Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1.". Nat. Med.. 6(1): 41-48. (2000). (PMID: 10613822).
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  36. González, M.V.; González-Sancho, J.M.; Caelles, C.; Munoz, A.; Jiménez, B. "Hormone-activated nuclear receptors inhibit the stimulation of the JNK and ERK signalling pathways in endothelial cells.". FEBS Lett.. 459(2): 272-276. (1999). (PMID: 10518034).
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  37. Gillis, P.; Savla, U.; Volpert, O.V.; Jimenez, B.; Waters, C.M.; Panos, R.J.; Bouck, N.P. "Keratinocyte growth factor induces angiogenesis and protects endothelial barrier function.". J. Cell. Sci.. 112 ( Pt 12)(): 2049-2057. (1999). (PMID: 10341222).
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  38. Lucas, R.; Holmgren, L.; Garcia, I.; Jimenez, B.; Mandriota, S.J.; Borlat, F.; Sim, B.K.; Wu, Z.; Grau, G.E.; Shing, Y.; Soff, G.A.; Bouck, N.; Pepper, M.S. "Multiple forms of angiostatin induce apoptosis in endothelial cells.". Blood. 92(12): 4730-4741. (1998). (PMID: 9845539).
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  39. Esteve, P.; Embade, N.; Perona, R.; Jiménez, B.; del Peso, L.; León, J.; Arends, M.; Miki, T.; Lacal, J.C. "Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway.". Oncogene. 17(14): 1855-1869. (1998). (PMID: 9778052).
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  40. Carnero, A.; Jiménez, B. "Effect of microinjection of rap 2A point mutant proteins on maturation and mottling in Xenopus oocytes.". Biochem. Biophys. Res. Commun.. 216(3): 748-754. (1995). (PMID: 7488189).
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  41. Jiménez, B.; del Peso, L.; Montaner, S.; Esteve, P.; Lacal, J.C. "Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation.". J. Cell. Biochem.. 57(1): 141-149. (1995). (PMID: 7721953).
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  42. Carnero, A.; Jiménez, B.; Lacal, J.C. "Progesterone but not ras requires MPF for in vivo activation of MAPK and S6 KII: MAPK is an essential conexion point of both signaling pathways.". J. Cell. Biochem.. 55(4): 465-476. (1994). (PMID: 7962177).
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  43. Cuadrado, A.; Carnero, A.; Dolfi, F.; Jiménez, B.; Lacal, J.C. "Phosphorylcholine: a novel second messenger essential for mitogenic activity of growth factors.". Oncogene. 8(11): 2959-2968. (1993). (PMID: 8414498).
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  44. Mollinedo, F.; Perez-Sala, D.; Gajate, C.; Jimenez, B.; Rodriguez, P.; Lacal, J.C. "Localization of rap1 and rap2 proteins in the gelatinase-containing granules of human neutrophils.". FEBS Lett.. 326(1-3): 209-214. (1993). (PMID: 8391995).
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  45. Perona, R.; Esteve, P.; Jiménez, B.; Ballestero, R.P.; Ramón y Cajal, S.; Lacal, J.C. "Tumorigenic activity of rho genes from Aplysia californica.". Oncogene. 8(5): 1285-1292. (1993). (PMID: 8479750).
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  46. Schwandner, W.R.; Jiménez, B.; Schwartz, A.; Weijer, C.J.; Behrens, M.; Mazón, M.J.; Fernández-Renart, M. "Chemotactic stimulation of aggregation-stage Dictyostelium cells induces rapid changes in energy metabolism, as measured by succinic thiokinase phosphorylation.". Biochim. Biophys. Acta. 1176(1-2): 175-182. (1993). (PMID: 8384004).
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  47. Jimenez, B.; Pizon, V.; Lerosey, I.; Béranger, F.; Tavitian, A.; de Gunzburg, J. "Effects of the ras-related rap2 protein on cellular proliferation.". Int. J. Cancer. 49(3): 471-479. (1991). (PMID: 1833345).
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  48. Jiménez, B.; Pestaña, A.; Fernandez-Renart, M. "A phospholipid-stimulated protein kinase from Dictyostelium discoideum.". Biochem. J.. 260(2): 557-561. (1989). (PMID: 2764888).
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  49. Jímenez, B.; Van Lookeren Campagne, M.M.; Pestaña, A.; Fernández-Renart, M. "Regulation of diacylglycerol kinase in the transition from quiescence to proliferation in Dictyostelium discoideum.". Biochem. Biophys. Res. Commun.. 150(1): 118-125. (1988). (PMID: 2827662).
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  50. Jímenez, B.; Fernandez-Renart, M.; Pestaña, A. "Changes in the plasma membrane ATPase activity in relationship to cell proliferation in Dictyostelium.". Biochem. Biophys. Res. Commun.. 141(3): 1092-1098. (1986). (PMID: 2880581).
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  51. Agullo, L.; Jimenez, B.; Aragón, C.; Giménez, C. "Beta-alanine transport in synaptic plasma membrane vesicles from rat brain. Efflux, exchange and stoichiometry.". Eur. J. Biochem.. 159(3): 611-617. (1986). (PMID: 3093232).
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